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1-Naphthalenol

$43

  • Brand : BIOFRON

  • Catalogue Number : BF-N3010

  • Specification : 98%

  • CAS number : 90-15-3

  • Formula : C10H8O

  • Molecular Weight : 144.173

  • Volume : 25mg

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Catalogue Number

BF-N3010

Analysis Method

HPLC,NMR,MS

Specification

98%

Storage

2-8°C

Molecular Weight

144.173

Appearance

powder

Botanical Source

Structure Type

Phenolics

Category

SMILES

C1=CC=C2C(=C1)C=CC=C2O

Synonyms

IUPAC Name

Density

1.2±0.1 g/cm3

Solubility

Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.

Flash Point

144.0±10.6 °C

Boiling Point

288.0±0.0 °C at 760 mmHg

Melting Point

94-98ºC

InChl

InChI=1S/C10H8O/c11-10-7-3-5-8-4-1-2-6-9(8)10/h1-7,11H

InChl Key

KJCVRFUGPWSIIH-UHFFFAOYSA-N

WGK Germany

RID/ADR

HS Code Reference

2907150000

Personal Projective Equipment

Correct Usage

For Reference Standard and R&D, Not for Human Use Directly.

Meta Tag

provides coniferyl ferulate(CAS#:90-15-3) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of coniferyl ferulate are included as well.>> amp version: coniferyl ferulate

PMID

32247241

Abstract

1-naphthol (1-NAP) is the main metabolite of pesticide carbaryl and naphthalene, and is also a genotoxic and carcinogenic intermediate in the synthesis of organic compound, dyes, pigment and pharmaceutical industry. In this work, two novel haptens were designed and synthesized for developing a competitive indirect enzyme-linked immunosorbent assay (ciELISA) method for 1-NAP in urine samples. The assay showed a limit of detection of 2.21 ng/mL and working range from 4.02 ng/mL to 31.25 ng/mL for 1-NAP in optimized working buffer. The matrix effect of samples was eliminated via 15-fold dilution of optimized working buffer. Good average recoveries (102.4%-123.4%) with a coefficient of variation from 11.7% to 14.7% was obtained for spiked urine samples. Subsequent instrument verification test showed good correlation between the results of ciELISA and high-performance liquid chromatography. The developed ciELISA is a high-throughput tool to monitor 1-NAP in urine, which can provide technical support for the establishment of biological exposure level for the exposure to carbaryl, naphthalene and other related pollutants.

KEYWORDS

1-naphthol; Hapten design; Immunoassay; Monoclonal antibody.

Title

Production of a specific monoclonal antibody for 1-naphthol based on novel hapten strategy and development of an easy-to-use ELISA in urine samples

Author

Zi-Jian Chen 1, Xi-Xia Liu 2, Zhi-Li Xiao 3, Hui-Jun Fu 4, Yu-Ping Huang 5, Shu-Yi Huang 6, Yu-Dong Shen 7, Fan He 8, Xing-Xing Yang 9, Bruce Hammock 10, Zhen-Lin Xu 11

Publish date

2020 Jun 15

PMID

31715455

Abstract

This study demonstrates that significant perturbation of tween20:cholesterol(1:1) niosome membrane takes place even at premicellar concentration of bile salts. Here, 1-naphthol (1-NpOH), a known and sensitive excited state proton transfer (ESPT) probe, was used to understand the nature of perturbation of the membrane in an unbuffered medium. The significant decrease in 1-NpOH fluorescence intensity in niosome-bile salt mixed system at both lower (10 °C) and higher (50 °C) temperatures indicates the bile salts [sodium cholate (NaC) and sodium deoxycholate (NaDC)] induce perturbation of niosome membranes. Variations in the fluorescence lifetime values of both the prototropic emissions (neutral and anionic species) along with the proton transfer rate of 1-NpOH confirm the bile salts perturb up to the hydrophobic core domain of the niosomal membranes. Bile salts induce size change of the niosomal membrane is confirmed through dynamic light scattering study.

KEYWORDS

Bile salts; Hydration; Niosome.

Title

Significant bile salt induced perturbation of niosome membrane: A molecular level interaction study using 1-Naphthol fluorescence

Author

Jhili Mishra 1, Ashok Kumar Mishra 2

Publish date

2020 Jan 1;

PMID

31107549

Abstract

For addressing the issues of pesticide residue analysis characterized by the trace levels of target analytes and the complexity of sample matrices, a selective extracting material, carbon nanotubes (CNTs)/β-cyclodextrin (β-CD) nanocomposite reinforced hollow fiber (HF), was developed. CNTs were chemically modified with β-CD and then the resultant nanocomposite was immobilized into the wall pores and lumen of HF by sol-gel technology. The reinforced HF was applied to direct-immersion mode of solid phase microextraction for the determination of carbaryl and 1-naphthol in tomatoes, coupled with high performance liquid chromatography. The proposed method provided 240- and 215-fold enrichment factors, good linearity in the range of 0.6 to 600 ng/g and 0.2 to 600 ng/g, good repeatability with RSDs of 4.5% and 6.9%, and batch-to-batch reproducibility with RSDs of 7.4% and 8.3% for 1-naphthol and carbaryl, respectively. Moreover, the low limits of detection at 0.05 and 0.15 ng/g for 1-naphthol and carbaryl, respectively, along with the high recovery in the range of 84.2% to 108.9% were obtained. The results showed that the material combined the respective advantages of CNTs, β-CD, and HF, thus, exhibiting efficient adsorption property, outstanding molecular recognition performance, and excellent sample clean-up effect, and it is applicable for pesticide residue analysis in complex matrices. PRACTICAL APPLICATION: The developed extracting material can be used for pesticide residue analysis of tomatoes. Pesticides, carbaryl, and 1-naphthol were detected in tomatoes, the most popular vegetable grown and consumed globally. The results supported the necessity to monitor pesticide residue for public health.

KEYWORDS

carbon nanotubes; food safety; hollow fiber; pesticide residue; solid-phase microextraction; β-cyclodextrin.

Title

Analysis of Pesticide Residue in Tomatoes by Carbon Nanotubes/β-Cyclodextrin Nanocomposite Reinforced Hollow Fiber Coupled with HPLC

Author

Yawen Ding 1, Xinyue Song 2, Juan Chen 1

Publish date

2019 Jun


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