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10-Hydroxymajoroside

$1,056

  • Brand : BIOFRON

  • Catalogue Number : BN-O0977

  • Specification : 97%(HPLC)

  • CAS number : 259753-12-3

  • Formula : C17H24O11

  • Molecular Weight : 404.37

  • PUBCHEM ID : 146013827

  • Volume : 5mg

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Catalogue Number

BN-O0977

Analysis Method

HPLC,NMR,MS

Specification

97%(HPLC)

Storage

2-8°C

Molecular Weight

404.37

Appearance

Powder

Botanical Source

Structure Type

Iridoids

Category

Standards;Natural Pytochemical;API

SMILES

COC(=O)C1=COC(C2=C(C(CC12)O)CO)OC3C(C(C(C(O3)CO)O)O)O

Synonyms

methyl (1S,4aS,6S)-6-hydroxy-7-(hydroxymethyl)-1-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-1,4a,5,6-tetrahydrocyclopenta[c]pyran-4-carboxylate

IUPAC Name

methyl (1S,4aS,6S)-6-hydroxy-7-(hydroxymethyl)-1-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-1,4a,5,6-tetrahydrocyclopenta[c]pyran-4-carboxylate

Density

Solubility

Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.

Flash Point

Boiling Point

Melting Point

InChl

InChI=1S/C17H24O11/c1-25-15(24)8-5-26-16(11-6(8)2-9(20)7(11)3-18)28-17-14(23)13(22)12(21)10(4-19)27-17/h5-6,9-10,12-14,16-23H,2-4H2,1H3/t6-,9+,10-,12-,13+,14-,16+,17+/m1/s1

InChl Key

IWDXNCIWSRAIAR-OCGKWZSUSA-N

WGK Germany

RID/ADR

HS Code Reference

2933990000

Personal Projective Equipment

Correct Usage

For Reference Standard and R&D, Not for Human Use Directly.

Meta Tag

provides coniferyl ferulate(CAS#:259753-12-3) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of coniferyl ferulate are included as well.>> amp version: coniferyl ferulate

No Technical Documents Available For This Product.

PMID

31186007

Abstract

Methods
Using the UK Biobank dataset, we extracted data on 36 chronic conditions and defined multimorbidity as (a) 2 or more conditions, (b) 2 or more conditions combined with self-reported overall health, and (c) 2 or more top-10 most common comorbidities. Leisure-time PA (LTPA) and total PA (TPA) were measured by questionnaire and categorised as low (< 600 metabolic equivalent (MET)-min/week), moderate (600 to < 3000 MET-min/week), and high (≥ 3000 MET-min/week), while objectively assessed PA was assessed by wrist-worn accelerometer and categorised as low (4 min/day), moderate (10 min/day), and high (22 min/day) walking at brisk pace. Survival models were applied to calculate adjusted hazard ratios (HRs) and predict life expectancy differences. Results 491,939 individuals (96,622 with 2 or more conditions) had a median follow-up of 7.0 (IQR 6.3-7.6) years. Compared to low LTPA, for participants with multimorbidity, HR for mortality was 0.75 (95% CI 0.70-0.80) and 0.65 (0.56-0.75) in moderate and high LTPA groups, respectively. This finding was consistent when using TPA measures. Using objective PA, HRs were 0.49 (0.29-0.80) and 0.29 (0.13-0.61) in the moderate and high PA groups, respectively. These findings were similar for participants without multimorbidity. In participants with multimorbidity, at the age of 45 years, moderate and high LTPA were associated with an average of 3.12 (95% CI 2.53, 3.71) and 3.55 (2.34, 4.77) additional life years, respectively, compared to low LTPA; in participants without multimorbidity, corresponding figures were 1.95 (1.59, 2.31) and 1.85 (1.19, 2.50). Similar results were found with TPA. For objective PA, moderate and high levels were associated with 3.60 (− 0.60, 7.79) and 5.32 (− 0.47, 11.11) life years gained compared to low PA for those with multimorbidity and 3.88 (1.79, 6.00) and 4.51 (2.15, 6.88) life years gained in those without. Results were consistent when using other definitions of multimorbidity. Conclusions There was an inverse dose-response association between PA and mortality. A moderate exercise is associated with a longer life expectancy, also in individuals with multimorbidity. Electronic supplementary material The online version of this article (10.1186/s12916-019-1339-0) contains supplementary material, which is available to authorized users.

KEYWORDS

Multimorbidity, Co-morbidity, Physical activity, Life expectancy, Mortality, UK Biobank

Title

Physical activity, multimorbidity, and life expectancy: a UK Biobank longitudinal study

Author

Yogini V. Chudasama,corresponding author1,2 Kamlesh K. Khunti,1,2 Francesco Zaccardi,1 Alex V. Rowlands,1,3,4 Thomas Yates,1,3 Clare L. Gillies,1 Melanie J. Davies,1,3 and Nafeesa N. Dhalwani1,2,5

Publish date

2019;

PMID

27053650

Abstract

To determine the metabolic response to food deprivation, cuttlefish (Sepia officinalis) juveniles were either fed, fasted (3 to 5 days food deprivation), or starved (12 days food deprivation). Fasting resulted in a decrease in triglyceride levels in the digestive gland, and after 12 days, these lipid reserves were essentially depleted. Oxygen consumption was decreased to 53% and NH4 excretion to 36% of the fed group following 3-5 days of food deprivation. Oxygen consumption remained low in the starved group, but NH4 excretion returned to the level recorded for fed animals during starvation. The fractional rate of protein synthesis of fasting animals decreased to 25% in both mantle and gill compared with fed animals and remained low in the mantle with the onset of starvation. In gill, however, protein synthesis rate increased to a level that was 45% of the fed group during starvation. In mantle, starvation led to an increase in cathepsin A-, B-, H-, and L-like enzyme activity and a 2.3-fold increase in polyubiquitin mRNA that suggested an increase in ubiquitin-proteasome activity. In gill, there was a transient increase in the polyubiquitin transcript levels in the transition from fed through fasted to the starved state and cathepsin A-, B-, H-, and L-like activity was lower in starved compared with fed animals. The response in gill appears more complex, as they better maintain rates of protein synthesis and show no evidence of enhanced protein breakdown through recognized catabolic processes.

KEYWORDS

NH4 production, ammonia quotient, cathepsin, triglyceride, digestive gland, proteasome, polyubiquitin

Title

Metabolic rate and rates of protein turnover in food-deprived cuttlefish, Sepia officinalis (Linnaeus 1758)

Author

Simon G. Lamarre,corresponding author1 Tyson J. MacCormack,2 Antonio V. Sykes,3 Jennifer R. Hall,4 Ben Speers-Roesch,5 Neal I. Callaghan,2 and William R. Driedzic5

Publish date

2016 Jun 1;

PMID

28325969

Abstract

The genus Calliscelio Ashmead is presumed to be a diverse group of parasitoids of the eggs of crickets (Orthoptera: Gryllidae). A least one species has been found to be an important factor in depressing cricket pest populations. The New World species of Calliscelio are revised. Forty-two species are recognized, 3 are redescribed: Calliscelio bisulcatus (Kieffer), Calliscelio laticinctus Ashmead, Calliscelio rubriclavus (Ashmead), comb. n.; and 38 are described as new: Calliscelio absconditum Chen & Johnson, sp. n., Calliscelio absum Chen & Johnson, sp. n., Calliscelio alcoa Chen & Masner, sp. n., Calliscelio amadoi Chen & Johnson, sp. n., Calliscelio armila Chen & Masner, sp. n., Calliscelio bidens Chen & Masner, sp. n., Calliscelio brachys Chen & Johnson, sp. n., Calliscelio brevinotaulus Chen & Johnson, sp. n., Calliscelio brevitas Chen & Johnson, sp. n., Calliscelio carinigena Chen & Johnson, sp. n., Calliscelio crater Chen & Johnson, sp. n., Calliscelio crena Chen & Johnson, sp. n., Calliscelio eboris Chen & Johnson, sp. n., Calliscelio extenuatus Chen & Johnson, sp. n., Calliscelio flavicauda Chen & Johnson, sp. n., Calliscelio foveolatus Chen & Johnson, sp. n., Calliscelio gatineau Chen & Johnson, sp. n., Calliscelio glaber Chen & Masner, sp. n., Calliscelio granulatus Chen & Masner, sp. n., Calliscelio latifrons Chen & Johnson, sp. n., Calliscelio levis Chen & Johnson, sp. n., Calliscelio longius Chen & Johnson, sp. n., Calliscelio magnificus Chen & Masner, sp. n., Calliscelio migma Chen & Johnson, sp. n., Calliscelio minutia Chen & Johnson, sp. n., Calliscelio paraglaber Chen & Johnson, sp. n., Calliscelio pararemigio Chen & Masner, sp. n., Calliscelio prolixus Chen & Johnson, sp. n., Calliscelio punctatifrons Chen & Johnson, sp. n., Calliscelio remigio Chen & Masner, sp. n., Calliscelio ruga Chen & Johnson, sp. n., Calliscelio rugicoxa Chen & Masner, sp. n., Calliscelio sfina Chen & Johnson, sp. n., Calliscelio storea Chen & Johnson, sp. n., Calliscelio suni Chen & Johnson, sp. n., Calliscelio telum Chen & Johnson, sp. n., Calliscelio torqueo Chen & Johnson, sp. n., Calliscelio virga Chen & Johnson, sp. n. Four species are treated as junior synonyms of Calliscelio rubriclavus (Ashmead): Anteris nigriceps Ashmead, syn. n., Caloteleia marlattii Ashmead, syn. n., Caloteleia grenadensis Ashmead, syn. n., and Macroteleia ruskini Girault, syn. n.

KEYWORDS

Egg parasitoid, key, revision, Gryllidae

Title

New World species of the genus Calliscelio Ashmead (Hymenoptera, Platygastridae, Scelioninae)

Author

Hua-yan Chen,1 Lubomir Masner,2 and Norman F. Johnson3

Publish date

2017;


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