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1D-chiro-Inositol

$118

  • Brand : BIOFRON

  • Catalogue Number : AV-C10601

  • Specification : 98%

  • CAS number : 643-12-9

  • Formula : C6H12O6

  • Molecular Weight : 180.16

  • PUBCHEM ID : 892

  • Volume : 20mg

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Catalogue Number

AV-C10601

Analysis Method

HPLC,NMR,MS

Specification

98%

Storage

2-8°C

Molecular Weight

180.16

Appearance

Botanical Source

Structure Type

Category

Standards;Natural Pytochemical;API

SMILES

C1(C(C(C(C(C1O)O)O)O)O)O

Synonyms

cyclohexanehexol/D-Inositol/(1R,2R,3S,4S,5S,6S)-1,2,3,4,5,6-Cyclohexanehexol/1,2,3,4,5,6-Cyclohexanehexol, (1α,2α,3β,4α,5β,6β)-/(1R,2R,3S,4S,5S,6S)-Cyclohexane-1,2,3,4,5,6-hexol/(1R,2R,3S,4S,5S,6S)-Cyclohexan-1,2,3,4,5,6-hexol/1,2,4/3,5,6-hexahydroxycyclohexane/1D-chiro-Inositol/(+)-1,2,4/3,5,6-Inositol/cis-inositol/D-Chiro-inositol(DCI)/D-CHIRO-INOSITOL(DISD)/D-(+)-Inositol/D-chiro-inositol

IUPAC Name

cyclohexane-1,2,3,4,5,6-hexol

Density

2.0±0.1 g/cm3

Solubility

Flash Point

143.4±21.9 °C

Boiling Point

291.3±40.0 °C at 760 mmHg

Melting Point

230 °C

InChl

InChl Key

WGK Germany

RID/ADR

HS Code Reference

2906130000

Personal Projective Equipment

Correct Usage

For Reference Standard and R&D, Not for Human Use Directly.

Meta Tag

provides coniferyl ferulate(CAS#:643-12-9) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of coniferyl ferulate are included as well.>> amp version: coniferyl ferulate

No Technical Documents Available For This Product.

PMID

25315464

Abstract

The monophosphinite ligands, 1D-1,2;5,6-di-O-cyclopentylidene-3-O-methyl-4-O-diphenylphosphino-chiro-inositol (D-P1), 1D-1,2;5,6-di-O-isopropylidene-3-O-methyl-4-O-diphenylphosphino-chiro-inositol (D-P2), 1D-1,2;5,6-di-O-cyclohexylidene-3-O-methyl-4-O-diphenylphosphino-chiro-inositol (D-P3), and 1D-1,2;5,6-di-O-cyclopentylidene-3-O-ethyl-4-O-diphenylphosphino-chiro-inositol (D-P4), can be conveniently prepared from the chiral natural products 1D-pinitol or 1D-chiro-inositol. On treatment of toluene solutions of RuCl2(PPh3)3 with two mole equivalents of the ligands D-PY (Y = 1-4) the complexes RuCl2(D-P1)2 (1), RuCl2(D-P2)2 (4), RuCl2(D-P3)2 (5), or RuCl2(D-P4)2 (6), respectively, are formed. Similarly, treatment of OsCl2(PPh3)3 with D-P1 gives OsCl2(D-P1)2 (7). The single crystal X-ray structure determination of 1 reveals that each D-P1 ligand coordinates to ruthenium through phosphorus and the oxygen atom of the methoxyl group. Treatment of 1 with excess LiBr or LiI results in metathesis of the chloride ligands and RuBr2(D-P1)2 (2) or RuI2(D-P1)2 (3), respectively, are formed. Exposure of a solution of 1 to carbon monoxide results in the very rapid formation of RuCl2(CO)2(D-P1)2 (8), thereby demonstrating the ease with which the oxygen donors are displaced from the metal and hence the hemilabile nature of the two bidentate D-P1 ligands in 1. Preliminary studies indicate that 1-7 act as catalysts for the asymmetric hydrogenation reactions of acetophenone and 3-quinuclidinone to give the corresponding alcohols in generally high conversions but low enantiomeric excesses.

Title

Ruthenium and osmium complexes of hemilabile chiral monophosphinite ligands derived from 1D-pinitol or 1D-chiro-inositol as catalysts for asymmetric hydrogenation reactions.

Author

Slade AT1, Lensink C, Falshaw A, Clark GR, Wright LJ.

Publish date

2014 Dec 7


Description :

D-chiro-Inositol is an epimer of myo-inositol found in certain mammalian glycosylphosphatidylinositol protein anchors and inositol phosphoglycans possessing insulin-like bioactivity. D-chiro-Inositol is used clinically for the treatment of polycystic ovary syndrome (PCOS) and diabetes mellitus, which can reduce hyperglycemia and ameliorate insulin resistance[1][2][3].