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(1S,2S)-1-Amino-2-Indanol

$64

  • Brand : BIOFRON

  • Catalogue Number : BN-O1065

  • Specification : 98%(HPLC)

  • CAS number : 163061-74-3

  • Formula : C9H11NO

  • Molecular Weight : 149.19

  • PUBCHEM ID : 6931156

  • Volume : 5mg

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Catalogue Number

BN-O1065

Analysis Method

Specification

98%(HPLC)

Storage

2-8°C

Molecular Weight

149.19

Appearance

Botanical Source

Structure Type

Category

SMILES

C1C(C(C2=CC=CC=C21)N)O

Synonyms

(1S,2S)-(+)-1-Amino-2-indanol/(1S,2S)-(+)-1-Amino-2-hydroxyindan

IUPAC Name

(1S,2S)-1-amino-2,3-dihydro-1H-inden-2-ol

Density

1.212 g/cm3

Solubility

Flash Point

129.2ºC

Boiling Point

290ºC at 760 mmHg

Melting Point

142-146ºC

InChl

InChl Key

LOPKSXMQWBYUOI-IUCAKERBSA-N

WGK Germany

RID/ADR

HS Code Reference

Personal Projective Equipment

Correct Usage

For Reference Standard and R&D, Not for Human Use Directly.

Meta Tag

provides coniferyl ferulate(CAS#:163061-74-3) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of coniferyl ferulate are included as well.>> amp version: coniferyl ferulate

No Technical Documents Available For This Product.

PMID

24010849

Abstract

Introduction
Several single-center studies and meta-analyses have shown that perioperative goal-directed therapy may significantly improve outcomes in general surgical patients. We hypothesized that using a treatment algorithm based on pulse pressure variation, cardiac index trending by radial artery pulse contour analysis, and mean arterial pressure in a study group (SG), would result in reduced complications, reduced length of hospital stay and quicker return of bowel movement postoperatively in abdominal surgical patients, when compared to a control group (CG).

Methods
160 patients undergoing elective major abdominal surgery were randomized to the SG (79 patients) or to the CG (81 patients). In the SG hemodynamic therapy was guided by pulse pressure variation, cardiac index trending and mean arterial pressure. In the CG hemodynamic therapy was performed at the discretion of the treating anesthesiologist. Outcome data were recorded up to 28 days postoperatively.

Results
The total number of complications was significantly lower in the SG (72 vs. 52 complications, p = 0.038). In particular, infection complications were significantly reduced (SG: 13 vs. CG: 26 complications, p = 0.023). There were no significant differences between the two groups for return of bowel movement (SG: 3 vs. CG: 2 days postoperatively, p = 0.316), duration of post anesthesia care unit stay (SG: 180 vs. CG: 180 minutes, p = 0.516) or length of hospital stay (SG: 11 vs. CG: 10 days, p = 0.929).

Conclusions
This multi-center study demonstrates that hemodynamic goal-directed therapy using pulse pressure variation, cardiac index trending and mean arterial pressure as the key parameters leads to a decrease in postoperative complications in patients undergoing major abdominal surgery.

Trial registration
ClinicalTrial.gov, NCT01401283.

Title

Perioperative goal-directed hemodynamic therapy based on radial arterial pulse pressure variation and continuous cardiac index trending reduces postoperative complications after major abdominal surgery: a multi-center, prospective, randomized study

Author

Cornelie Salzwedel,#1 Jaume Puig,#2 Arne Carstens,3 Berthold Bein,3 Zsolt Molnar,4 Krisztian Kiss,4 Ayyaz Hussain,5 Javier Belda,2 Mikhail Y Kirov,5 Samir G Sakka,6 and Daniel A Reutercorresponding author1

Publish date

2013;

PMID

18394150

Abstract

Background
A general education in psychiatry does not necessary lead to good diagnostic skills. Specific training programs in diagnostic coding are established to facilitate implementation of ICD-10 coding practices. However, studies comparing the impact of these two different educational approaches on diagnostic skills are lacking. The aim of the current study was to find out if a specific training program in diagnostic coding improves the diagnostic skills better than a general education program, and if a national bias in diagnostic patterns can be minimised by a specific training in diagnostic coding.

Methods
A pre post design study with two groups was carried in the county of Archangels, Russia. The control group (39 psychiatrists) took the required course (general educational program), while the intervention group (45 psychiatrists) were given a specific training in diagnostic coding. Their diagnostic skills before and after education were assessed using 12 written case-vignettes selected from the entire spectrum of psychiatric disorders.

Results
There was a significant improvement in diagnostic skills in both the intervention group and the control group. However, the intervention group improved significantly more than did the control group. The national bias was partly corrected in the intervention group but not to the same degree in the control group. When analyzing both groups together, among the background factors only the current working place impacted the outcome of the intervention.

Conclusion
Establishing an internationally accepted diagnosis seems to be a special skill that requires specific training and needs to be an explicit part of the professional educational activities of psychiatrists. It does not appear that that skill is honed without specific training. The issue of national diagnostic biases should be taken into account in comparative cross-cultural studies of almost any character. The mechanisms of such biases are complex and need further consideration in future research. Future research should also address the question as to whether the observed improvement in diagnostic skills after specific training actually leads to changes in routine diagnostic practice.

Title

Correcting biases in psychiatric diagnostic practice in Northwest Russia: Comparing the impact of a general educational program and a specific diagnostic training program

Author

Grigory Rezvyy,corresponding author1 Alexander Parniakov,2 Elena Fedulova,3 and Reidun Olstad4,5

Publish date

2008

PMID

22681916

Abstract

Background
Diets rich in omega-3 fatty acids and low in saturated fat were found beneficially associated with blood lipids and cardio-vascular health. Lean reindeer meet and local cold water white-fish species high in omega-3 are among the main sources of nutrients in the rural area of the Nenets Autonomous Okrug (NAO) in Russia and are not normally consumed by the urban population from the same region. The aims of the study were firstly, to compare serum lipid profiles of residents of urban (Arkhangelsk city) and rural (NAO) regions of Arkhangelsk County, and secondly, to investigate the effects of fish consumption on the predictor of cardiovascular events apolipoprotein (Apo) B/ApoA-I ratio in these populations.

Methods
A cross-sectional study conducted in Arkhangelsk County, Russia. Sample size of 249 adults: 132 subjects from Arkhangelsk city, aged 21-70 and 117 subject (87% Ethnic Nenets) from NAO, aged 18-69.

Results
We observed more favorable lipid levels in NAO compared to Arkhangelsk participants. Age-adjusted geometric means of ApoB/ApoA-I ratio were 1.02 and 0.98 in men and women from Arkhangelsk; 0.84 and 0.91 in men and women from NAO respectively. Age and consumption of animal fat were positively associated with ApoB/ApoA-I ratio in women (pooled samples from Arkhangelsk and NAO). Body mass index and low levels of physical activity were positively associated with ApoB/ApoA-I ratio in men (pooled samples from Arkhangelsk and NAO). Reported oily fish consumption was not significantly correlated with ApoB/ApoA-I ratio.

Conclusion
The population sample from rural NAO, consisting largely of the indigenous Arctic population Nenets with healthier dietary sources, had a relatively less atherogenic lipid profile compared to the urban Arkhangelsk group. Fish consumption had no effect on apolipoproteins profile.

KEYWORDS

Serum lipids, Apolipoprotein A-I, Apolipoprotein B, Apolipoprotein B/ Apolipoprotein A-I ratio, Fish consumption, Nenets Autonomous Okrug, Arkhangelsk County

Title

Serum apolipoproteins in relation to intakes of fish in population of Arkhangelsk County

Author

Natalia Petrenya,corresponding author1 Magritt Brustad,2 Marie Cooper,1 Liliya Dobrodeeva,3 Fatima Bichkaeva,3 Gulnara Lutfalieva,3 and Jon Øyvind Odland4

Publish date

2012;


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