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2,3,8-Tri-O-methylellagic acid

$1,248

  • Brand : BIOFRON

  • Catalogue Number : BN-O1596

  • Specification : 98%(HPLC)

  • CAS number : 1617-49-8

  • Formula : C17H12O8

  • Molecular Weight : 344.3

  • PUBCHEM ID : 5281860

  • Volume : 5mg

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Catalogue Number

BN-O1596

Analysis Method

HPLC,NMR,MS

Specification

98%(HPLC)

Storage

-20℃

Molecular Weight

344.3

Appearance

Powder

Botanical Source

This product is isolated and purified from the herbs of Combretum paniculatum.

Structure Type

Phenols

Category

Standards;Natural Pytochemical;API

SMILES

COC1=C(C2=C3C(=C1)C(=O)OC4=C3C(=CC(=C4OC)O)C(=O)O2)OC

Synonyms

3,7,8-tri-O-methylellagic acid/3,4,3'-tri-O-methylellagic acid/3,3',4'-tri-O-methylellagic acid/[1]Benzopyrano[5,4,3-cde][1]benzopyran-5,10-dione, 2-hydroxy-3,7,8-trimethoxy-/1,2,8-tri-O-methylellagic acid/(1)Benzopyrano(5,4,3-cde)(1)benzopyran-5,10-dione, 2-hydroxy-3,7,8-trimethoxy-/2-Hydroxy-3,7,8-trimethoxychromeno[5,4,3-cde]chromene-5,10-dione/3,3',4'-trimethoxy-ellagic acid/2,3,8-Tri-O-methylellagic acid

IUPAC Name

6-hydroxy-7,13,14-trimethoxy-2,9-dioxatetracyclo[6.6.2.04,16.011,15]hexadeca-1(15),4,6,8(16),11,13-hexaene-3,10-dione

Density

1.5±0.1 g/cm3

Solubility

Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.

Flash Point

237.5±25.0 °C

Boiling Point

630.0±55.0 °C at 760 mmHg

Melting Point

InChl

InChl Key

LXEQIOGTMDLLEC-UHFFFAOYSA-N

WGK Germany

RID/ADR

HS Code Reference

2914500000

Personal Projective Equipment

Correct Usage

For Reference Standard and R&D, Not for Human Use Directly.

Meta Tag

provides coniferyl ferulate(CAS#:1617-49-8) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of coniferyl ferulate are included as well.>> amp version: coniferyl ferulate

No Technical Documents Available For This Product.

PMID

25895388

Abstract

Objective: To investigate the chemical constituents from Canarium pimela fruits.

Methods: Compounds were obtained after separation and purification by silica gel and Sephadex LH-20. The structures were identified on the basis of physico-chemical properties and spectrum data.

Results: Eight compounds were isolated from Canarium pimela fruits. The structures were identified as amentoflavone (1), kaempferol-3-O-β-D-galactopyranoside (2), shikimic acid (3), quercetin (4), kaempferol (5), 3,3′-di-O-methylellagic acid (6), 3,3′,4-tri-O-methylellagic acid (7) and stigmasterol (8).

Conclusion: Compounds 1-8 are isolated from Canarium pimela fruits for the first time.

Title

[Chemical Constituents From Canarium Pimela Fruits]

Author

Zhen-cheng Lv, Yan Yin, Li-jing Lin, Yong-hong Peng

Publish date

2014 Oct;

PMID

24879588

Abstract

Using a bioassay-directed chromatographic separation, two ellagic acids were obtained from the ethyl acetate extract of the roots of Sanguisorba officinalis L. On the basis of chemical and spectroscopic methods, the two ellagic acids were identified as 3,3′,4-tri-O-methylellagic acid-4′-O-β-d-xyloside and 3,3′,4-tri-O-methylellagic acid. Stimulation of cell proliferation was assayed in hematopoietic progenitor cells using the Cell Counting kit-8 method. The megakaryocyte differentiation was determined in human erythroleukemia (HEL) cells using Giemsa staining and flow cytometry analysis. The ellagic acids significantly stimulated the proliferation of Baf3/Mpl cells. Morphology analysis and megakaryocyte specific-marker CD41 staining confirmed that the ellagic acids induced megakaryocyte differentiation in HEL cells. This is the first time that 3,3′,4-tri-O-methylellagic acid or 3,3′,4-tri-O-methylellagic acid-4′-O-β-d-xyloside are reported to induce megakaryopoiesis, suggesting a class of small molecules which differ from others non-peptidyl, and appears to have potential for clinical development as a therapeutic agent for patients with blood platelet disorders.

Title

Two Ellagic Acids Isolated From Roots of Sanguisorba Officinalis L. Promote Hematopoietic Progenitor Cell Proliferation and Megakaryocyte Differentiation

Author

Xiaoping Gao 1, Jianming Wu 2, Wenjun Zou 3, Yanping Dai 4

Publish date

2014 Apr 24

PMID

8703340

Abstract

Three compounds have been isolated from the root of Euphorbia hylonoma and identified as 3,3′,4-tri-O- methylellagic acid, beta-sitosterol and sucrose by physicochemical and spectroscopic methods. The compound 3,3’4-tri-O-methylellagic acid is discovered in Euphorbia for the first time.

Title

[Chemical Constituents of Euphorbia Hylonoma Hand. -Mazz]

Author

Z Guo 1, R Zhu, J Lu, Y Li

Publish date

1995 Dec;


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