We Offer Worldwide Shipping
Login Wishlist

2,6-Dimethoxy-1-acetonylquinol

$960

  • Brand : BIOFRON

  • Catalogue Number : BN-O1552

  • Specification : 98%(HPLC)

  • CAS number : 2215-96-5

  • Formula : C11H14O5

  • Molecular Weight : 226.2

  • PUBCHEM ID : 241783

  • Volume : 5mg

Available on backorder

Quantity
Checkout Bulk Order?

Catalogue Number

BN-O1552

Analysis Method

HPLC,NMR,MS

Specification

98%(HPLC)

Storage

-20℃

Molecular Weight

226.2

Appearance

Yellow powder

Botanical Source

This product is isolated and purified from the barks of Ailanthus altissima

Structure Type

Quinones

Category

Standards;Natural Pytochemical;API

SMILES

CC(=O)CC1(C(=CC(=O)C=C1OC)OC)O

Synonyms

4-acetonyl-4-hydroxy-3,5-dimethoxy-cyclohexa-2,5-dienone/4-Hydroxy-3,5-dimethoxy-4-(2-oxopropyl)-2,5-cyclohexadien-1-one/1-Acetonyl-2,6-dimethoxy-chinol/2,6-dimethoxy-1-acetonylquinol/4-Acetonyl-4-hydroxy-3,5-dimethoxy-cyclohexa-2,5-dienon/3,5-Dimethoxy-4-acetonyl-p-chinol/2,5-Cyclohexadien-1-one, 4-hydroxy-3,5-dimethoxy-4-(2-oxopropyl)-/4-acetonyl-3,5-dimethoxy-p-quinol

IUPAC Name

4-hydroxy-3,5-dimethoxy-4-(2-oxopropyl)cyclohexa-2,5-dien-1-one

Density

1.2±0.1 g/cm3

Solubility

Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.

Flash Point

181.1±22.2 °C

Boiling Point

457.5±45.0 °C at 760 mmHg

Melting Point

InChl

InChl Key

KMNCHTPRXWQOIZ-UHFFFAOYSA-N

WGK Germany

RID/ADR

HS Code Reference

2914500000

Personal Projective Equipment

Correct Usage

For Reference Standard and R&D, Not for Human Use Directly.

Meta Tag

provides coniferyl ferulate(CAS#:2215-96-5) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of coniferyl ferulate are included as well.>> amp version: coniferyl ferulate

No Technical Documents Available For This Product.

PMID

23821350

Abstract

Purpose
Magnetic resonance imaging (MRI)-based techniques for assessing liver iron concentration (LIC) have been limited by single scanner calibration against biopsy. Here, the calibration of spin-density projection-assisted (SDPA) R2-MRI (FerriScan®) in iron-overloaded β-thalassemia patients treated with the iron chelator, deferasirox, for 12 months is validated.

Methods
SDPA R2-MRI measurements and percutaneous needle liver biopsy samples were obtained from a subgroup of patients (n = 233) from the ESCALATOR trial. Five different makes and models of scanner were used in the study.

Results
LIC, derived from mean of MRI- and biopsy-derived values, ranged from 0.7 to 50.1 mg Fe/g dry weight. Mean fractional differences between SDPA R2-MRI- and biopsy-measured LIC were not significantly different from zero. They were also not significantly different from zero when categorized for each of the Ishak stages of fibrosis and grades of necroinflammation, for subjects aged 3 to <8 versus ≥8 years, or for each scanner model. Upper and lower 95% limits of agreement between SDPA R2-MRI and biopsy LIC measurements were 74 and −71%. Conclusion The calibration curve appears independent of scanner type, patient age, stage of liver fibrosis, grade of necroinflammation, and use of deferasirox chelation therapy, confirming the clinical usefulness of SDPA R2-MRI for monitoring iron overload. Magn Reson Med 71:2215-2223, 2014. © 2013 Wiley Periodicals, Inc.

KEYWORDS

deferasirox, iron overload, β-thalassemia, ESCALATOR, biopsy

Title

Multicenter Validation of Spin-Density Projection-Assisted R2-MRI for the Noninvasive Measurement of Liver Iron Concentration

Author

Tim G St Pierre,* Amal El-Beshlawy, Mohsen Elalfy, Abdullah Al Jefri, Kusai Al Zir, Shahina Daar, Dany Habr, Ulrike Kriemler-Krahn, and Ali Taher

Publish date

2014 Jan

PMID

29807017

Abstract

Carotid body glomus cells mediate essential reflex responses to arterial blood hypoxia. They are dopaminergic and secrete growth factors that support dopaminergic neurons, making the carotid body a potential source of patient-specific cells for Parkinson’s disease therapy. Like adrenal chromaffin cells, which are also hypoxia-sensitive, glomus cells are neural crest-derived and require the transcription factors Ascl1 and Phox2b; otherwise, their development is little understood at the molecular level. Here, analysis in chicken and mouse reveals further striking molecular parallels, though also some differences, between glomus and adrenal chromaffin cell development. Moreover, histology has long suggested that glomus cell precursors are ‘emigres’ from neighbouring ganglia/nerves, while multipotent nerve-associated glial cells are now known to make a significant contribution to the adrenal chromaffin cell population in the mouse. We present conditional genetic lineage-tracing data from mice supporting the hypothesis that progenitors expressing the glial marker proteolipid protein 1, presumably located in adjacent ganglia/nerves, also contribute to glomus cells. Finally, we resolve a paradox for the ‘emigre’ hypothesis in the chicken – where the nearest ganglion to the carotid body is the nodose, in which the satellite glia are neural crest-derived, but the neurons are almost entirely placode-derived – by fate-mapping putative nodose neuronal ’emigres’ to the neural crest.

KEYWORDS

Carotid body glomus cells, Adrenal chromaffin cells, Neural crest, Schwann cell precursors, Nodose neurons

Title

Striking parallels between carotid body glomus cell and adrenal chromaffin cell development

Author

Dorit Hockman,a,b,c,1 Igor Adameyko,d,e Marketa Kaucka,d Perrine Barraud,a Tomoki Otani,a Adam Hunt,a Anna C. Hartwig,f Elisabeth Sock,f Dominic Waithe,g Marina C.M. Franck,h,2 Patrik Ernfors,h Sean Ehinger,i,3 Marthe J. Howard,i Naoko Brown,j Jeffrey Reese,j and Clare V.H. Bakera,⁎

Publish date

2018 Dec 1;

PMID

10999861

Abstract

The association of maternal smoking and type of feeding with colic was assessed in 3345 children aged 1-6 months (96% response). The prevalence of colic was twofold higher among infants of smoking mothers, but less among breastfed infants. Maternal smoking as a potential risk factor for infantile crying needs further study.

Title

Infantile colic: maternal smoking as potential risk factor

Author

S. Reijneveld, E. Brugman, and R. Hirasing

Publish date

2000 Oct;


Description :

Empty ...