Catalogue Number
BN-O1171
Analysis Method
Specification
98%(HPLC)
Storage
2-8°C
Molecular Weight
151.16
Appearance
Botanical Source
Structure Type
Category
SMILES
CC1=C(C(=CC=C1)C(=O)O)N
Synonyms
2-Amino-3-methylbenzoic acid/3-Methylanthranilic acid/2-Amino-m-toluic Acid/2-Amino-3-methylbenzoicacid/Benzoic acid, 2-amino-3-methyl-/2-Amino-3-methyl benzoicacid
IUPAC Name
2-amino-3-methylbenzoic acid
Density
1.3±0.1 g/cm3
Solubility
Flash Point
144.4±24.6 °C
Boiling Point
315.1±30.0 °C at 760 mmHg
Melting Point
174-177 °C(lit.)
InChl
InChl Key
WNAJXPYVTFYEST-UHFFFAOYSA-N
WGK Germany
RID/ADR
HS Code Reference
Personal Projective Equipment
Correct Usage
For Reference Standard and R&D, Not for Human Use Directly.
Meta Tag
provides coniferyl ferulate(CAS#:4389-45-1) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of coniferyl ferulate are included as well.>> amp version: coniferyl ferulate
No Technical Documents Available For This Product.
3751122
Metabolism of lidocaine in rabbit liver 9000 g supernatant fraction was examined. A capillary g.l.c. assay was developed to separate seven known metabolites of lidocaine, and all seven metabolites were identified in extracts of incubations of lidocaine with rabbit-liver fractions. These metabolites were monoethylglycinexylidide(I), glycinexylidide(II), 3-hydroxymonoethylglycinexylidide(III), 3-hydroxylidocaine(IV), 4-hydroxylidocaine(V), xylidine(VI) and 4-hydroxyxylidine(VII). A new metabolite, 2-amino-3-methylbenzoic acid(VIII), was identified in extracts of incubations of lidocaine with rabbit-liver fractions, by comparison of the mass-spectral fragmentation patterns and g.l.c. retention time with those of the authentic compound. The formation of VIII is dependent on protein, NADPH, time, O2, and the presence of soluble enzymes. Quantitative analysis of metabolites I-VIII after a two hour incubation accounts for 89% of the metabolized lidocaine.
Lidocaine Metabolism by Rabbit-Liver Homogenate and Detection of a New Metabolite
R C Kammerer, D A Schmitz
1986 Jul;
15002967
The design, synthesis, characterization, and screening of a large, encoded thiazolidinone library are described. Three sets of 35 building blocks were combined by encoded split-pool synthesis to give a library containing more than 42 000 members. Building block selection was based in part on a novel small molecule follicle stimulating hormone receptor agonist hit and in part for diversity. HPLC/MS techniques were applied at the single-bead level to build confidence in the reliability of library construction. Application of two distinct screening strategies resulted in the identification of compounds with significantly improved potency over the initial hit. This work demonstrates the versatility of encoded libraries for preparing a large number of analogues of a given hit while simultaneously generating a large collection of compounds for screening against other targets.
Agonists of the Follicle Stimulating Hormone Receptor From an Encoded Thiazolidinone Library
Derek Maclean 1, Frank Holden, Ann M Davis, Randall A Scheuerman, Stephen Yanofsky, Christopher P Holmes, William L Fitch, Ken Tsutsui, Ronald W Barrett, Mark A Gallop
Mar-Apr 2004