Catalogue Number
BN-O1076
Analysis Method
Specification
98%(HPLC)
Storage
2-8°C
Molecular Weight
157.17
Appearance
Botanical Source
Structure Type
Category
SMILES
C1=CC=C2C(=C1)NC(=N2)CC#N
Synonyms
1H-Benzimidazol-2-ylacetonitrile/(1H-BENZOIMIDAZOL-2-YL)-ACETONITRILE/2-(1H-benzo[d]imidazol-2-yl)acetonitrile/1H-Benzimidazole-2-acetonitrile/2-(Cyanomethyl)benzimidazole
IUPAC Name
2-(1H-benzimidazol-2-yl)acetonitrile
Density
1.3±0.1 g/cm3
Solubility
Flash Point
142.5±9.2 °C
Boiling Point
439.5±28.0 °C at 760 mmHg
Melting Point
200-205 °C (dec.)(lit.)
InChl
InChl Key
BWOVACANEIVHST-UHFFFAOYSA-N
WGK Germany
RID/ADR
HS Code Reference
Personal Projective Equipment
Correct Usage
For Reference Standard and R&D, Not for Human Use Directly.
Meta Tag
provides coniferyl ferulate(CAS#:4414-88-4) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of coniferyl ferulate are included as well.>> amp version: coniferyl ferulate
No Technical Documents Available For This Product.
1852008
Interleukin 6 (IL-6) has been shown to inhibit the proliferation, but increase the motility, of wild-type ZR-75-1 human ductal breast carcinoma cells, a line of cells that resemble closely the malignant cells cultured from the ascitic effusion. IL-6-treated cells lose their epithelial character, become stellate or fusiform in shape, and migrate away from neighbors. In the wild-type ZR-75-1 cells, IL-6 causes cell-cell separation in preformed colonies as well as postmitotically. We have now investigated the action of IL-6 in clone B ZR-75-1 cells, which are morphologically distinct from wild-type ZR-75-1 cells. In the more polygonal rather than cuboidal clone B cells, IL-6 did not cause early inhibition of DNA synthesis and it caused little cell-cell separation in preformed colonies. However, IL-6 treatment markedly prolonged the interval between mitosis and readherence of daughter cells to their neighbors and the substratum. Supernatants from IL-6-treated cultures contained detached viable cells in increased numbers. Intermitotic intervals were prolonged in IL-6-treated cultures. IL-6-treated dividing breast carcinoma cells are characterized by an increased probability of separation from neighbors and the substratum.
Decreased adherence of interleukin 6-treated breast carcinoma cells can lead to separation from neighbors after mitosis.
I Tamm, I Cardinale, and J S Murphy
1991 May 15;
3859870
The induction of heat shock proteins in three species of Leishmania, L. tropica, L. enrietti, and L. donovani is reported. When cultures of promastigotes are shifted from 26 degrees C to 37 degrees C or 40 degrees C, the synthesis of proteins with apparent molecular weights of 88,000, 74,000, and 54,000 is stimulated. Actinomycin D added just prior to the shift prevented the appearance of these proteins but had no effect when present 30 min after the transfer onward, suggesting that the regulation of leishmanial heat shock proteins occurs at the transcriptional level. Exposure of L. tropica promastigotes to sodium arsenite elicits the synthesis of three major and four minor polypeptides. Their apparent molecular weights are, respectively, 94,000, 78,000, and 56,000 and 70,000, 45,000, 22,000, and 18,000. The response of Leishmania organisms to heat shock and to sodium arsenite is similar to that of other organisms, but some of the proteins identified as stress proteins in the parasite differ in size. The heat shock proteins might play a role in cytodifferentiation during the life cycle of the parasite and also in cellular adaptation to higher temperatures.
Induction of heat shock and stress proteins in promastigotes of three Leishmania species.
F Lawrence and M Robert-Gero
1985 Jul
8415014
High efficiency transformation of Saccharomyces cerevisiae by electroporation.
P Manivasakam and R H Schiestl
1993 Sep 11
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