Catalogue Number
BN-O1108
Analysis Method
Specification
98%(HPLC)
Storage
2-8°C
Molecular Weight
456.6
Appearance
Botanical Source
Structure Type
Category
SMILES
C1=CC=C(C=C1)C(=O)NC2=CC=CC=C2SSC3=CC=CC=C3NC(=O)C4=CC=CC=C4
Synonyms
Benzenecarboximidic acid, N,N'-(dithiodi-2,1-phenylene)bis-/3-13-00-00917 (Beilstein Handbook Reference)/2,2'-Dithiobisbenzan/o,o'-Dibenzamidodiphenyl disulfide/Benzanilide, 2',2'''-dithiobis-/N,N'-(Disulfanediyldi-2,1-phenylene)dibenzenecarboximidic acid/N,N'-(Disulfanediyldi-2,1-phenylene)dibenzamide/pepton22/2-Benzamidophenyl disulphide/peptazinbafd/2,2'-Dibenzamidodiphenyl disulfide/Di-o-benzamidophenyl disulphide/2,2'-Dithiodibenzanilide/2,2'-dithio-bis-N,N'-phenylbenzamide/3-13-00-00917/Bis(2-benzamidophenyl) Disulfide/N,N'-(disulfanediyldibenzene-2,1-diyl)dibenzamide/N,N'-Dithiodi-o-phenylenedibenzamide/peptisant1o/Peptisant-10/2-benzamidophenyl disulfide/Benzamide, N,N'-(dithiodi-2,1-phenylene)bis-/o-bensoylaminobenzene thiolate disulfide
IUPAC Name
N-[2-[(2-benzamidophenyl)disulfanyl]phenyl]benzamide
Density
1.2±0.1 g/cm3
Solubility
Flash Point
357.3±34.3 °C
Boiling Point
667.1±65.0 °C at 760 mmHg
Melting Point
143-146°C
InChl
InChl Key
ZHMIOPLMFZVSHY-UHFFFAOYSA-N
WGK Germany
RID/ADR
HS Code Reference
Personal Projective Equipment
Correct Usage
For Reference Standard and R&D, Not for Human Use Directly.
Meta Tag
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20923542
Introduction
There is a remarkable increase in cardiovascular disease after menopause. On the other hand, metabolic syndrome as a collection of risk factors has a known effect on cardiovascular diseases. Hormone changes are considered as one of the main relevant factor regarding cardiovascular disease as well as some recognized relationship with metabolic syndrome’s components. This study was carried out in order to search for prevalence of metabolic syndrome during menopausal transition.
Method
In a cross sectional study in urban and rural areas of Isfahan, Najafabad and Arak cities, 1596 women aged more than 45 years were investigated using Isfahan Healthy Heart Program’s (IHHP) samples. Participants were categorized into three groups of pre-menopause, menopause and post-menopause. Leisure time physical activity and global dietary index were included as life style factors. The association of metabolic syndrome and its components with menopausal transition considering other factors such as age and life style was analyzed.
Results
there were 303, 233 and 987 women in premenopausal, early menopausal and postmenopausal groups respectively. Metabolic syndrome was found in 136(44.9%) premenopausal participants and significantly increased to 135(57.9%) and 634(64.3%) in early menopausal and postmenopausal participants respectively, when age was considered (P = 0.010). Except for hypertension and hypertriglyceridemia, there was no significant difference between three groups of menopausal transition when metabolic syndrome’s components were considered.
Conclusion
In contrary to the claims regarding the role of waist circumference and blood glucose in increasing of metabolic syndrome during the menopausal transition, this study showed this phenomenon could be independence of them.
Metabolic syndrome in menopausal transition: Isfahan Healthy Heart Program, a population based study
Ramin Heidari,1 Masoumeh Sadeghi,corresponding author2 Mohammad Talaei,3 Katayoun Rabiei,4 Noushin Mohammadifard,5 and Nizal Sarrafzadegan2
2010
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