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3,7-O-Diacetylpinobanksin

$832

  • Brand : BIOFRON

  • Catalogue Number : BN-O1551

  • Specification : 98%(HPLC)

  • CAS number : 103553-98-6

  • Formula : C19H16O7

  • Molecular Weight : 356.3

  • PUBCHEM ID : 91884891

  • Volume : 5mg

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Catalogue Number

BN-O1551

Analysis Method

HPLC,NMR,MS

Specification

98%(HPLC)

Storage

-20℃

Molecular Weight

356.3

Appearance

Powder

Botanical Source

This product is isolated and purified from the barks of Pinus koraiensis

Structure Type

Flavonoids

Category

Standards;Natural Pytochemical;API

SMILES

CC(=O)OC1C(OC2=CC(=CC(=C2C1=O)O)OC(=O)C)C3=CC=CC=C3

Synonyms

Pinobanksin-3,7-diacetat/Pinanyltrimethylsilan/(2R,3R)-5-Hydroxy-4-oxo-2-phenyl-3,4-dihydro-2H-chromene-3,7-diyl diacetate/4H-1-Benzopyran-4-one, 3,7-bis(acetyloxy)-2,3-dihydro-5-hydroxy-2-phenyl-, (2R,3R)-

IUPAC Name

[(2R,3R)-7-acetyloxy-5-hydroxy-4-oxo-2-phenyl-2,3-dihydrochromen-3-yl] acetate

Density

1.4±0.1 g/cm3

Solubility

Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.

Flash Point

204.7±23.6 °C

Boiling Point

564.2±50.0 °C at 760 mmHg

Melting Point

InChl

InChI=1S/C19H16O7/c1-10(20)24-13-8-14(22)16-15(9-13)26-18(12-6-4-3-5-7-12)19(17(16)23)25-11(2)21/h3-9,18-19,22H,1-2H3/t18-,19+/m1/s1

InChl Key

JHHPBJCBJRYFGP-MOPGFXCFSA-N

WGK Germany

RID/ADR

HS Code Reference

2933990000

Personal Projective Equipment

Correct Usage

For Reference Standard and R&D, Not for Human Use Directly.

Meta Tag

provides coniferyl ferulate(CAS#:103553-98-6) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of coniferyl ferulate are included as well.>> amp version: coniferyl ferulate

No Technical Documents Available For This Product.

PMID

29171937

Abstract

Aims/Introduction
To evaluate the incidence rate of and identify factors associated with severe hypoglycemic episodes in patients with treated type 2 diabetes mellitus.

Materials and Methods
Using Diagnosis Procedure Combination hospital‐based medical database, we carried out a retrospective cohort study to assess the incidence rate of severe hypoglycemia in treated type 2 diabetes mellitus patients. We evaluated the associations between severe hypoglycemia and age, sex, complications, and current use of insulin or sulfonylurea (SU) in a nested case-control study.

Results
Of 166,806 eligible patients, 1,242 had episodes of severe hypoglycemia during the observational period. The incidence rate of the first hypoglycemic events was 3.70/1,000 patient years. Based on the nested case-control analysis, age was associated with hypoglycemic events with adjusted odds ratios (ORs) of 1.64 or 65-74‐year‐old patients and 3.79 for ≥75‐year‐old patients in comparison with 20-64‐year‐old patients. Comorbidities, such as cognitive impairment, cancer, macrovascular disease and diabetic complications (retinopathy, nephropathy and neuropathy), were associated with severe hypoglycemia, with adjusted ORs ranging from 1.25 to 3.80. Severe hypoglycemic events also increased in patients with current use of both SU and insulin, either SU or insulin, with adjusted ORs of 18.36, 6.31 or 14.07, respectively, compared with patients with other antihyperglycemic agents. In patients with an SU glimepiride, adjusted ORs increased dose‐dependently from 3.65 (≤1 mg) to 13.34 (>2 mg).

Conclusions
The incidence rate of severe hypoglycemia in this cohort was 3.70/1,000 patient years. Age, cognitive impairment, cancer, diabetic complications, current use of insulin + SU and SU dosage were identified as risk factors for severe hypoglycemia.

KEYWORDS

Database analysis, Hypoglycemia, Type 2 diabetes

Title

Incidence rate and patient characteristics of severe hypoglycemia in treated type 2 diabetes mellitus patients in Japan: Retrospective Diagnosis Procedure Combination database analysis

Author

Yuika Ikeda, 1 Takekazu Kubo,corresponding author 2 Eisei Oda, 3 Machiko Abe, 1 and Shigeru Tokita 2

Publish date

2018 Jul;

PMID

28163826

Abstract

We report here the draft genome sequences of eight bacterial strains of the genera Staphylococcus, Microbacterium, Mycobacterium, Plantibacter, and Pseudomonas. These isolates were obtained from aerosol sampling of bathrooms of five residences in the San Francisco Bay area. Taxonomic classifications as well as the genome sequence and gene annotation of the isolates are described. As part of the “Built Environment Reference Genome” project, these isolates and associated genome data provide valuable resources for studying the microbiology of the built environment.

Electronic supplementary material
The online version of this article (doi:10.1186/s40793-017-0223-9) contains supplementary material, which is available to authorized users.

KEYWORDS

Built environment, Shower water, Airborne bacteria, Bacterial genomes

Title

Draft genome sequences of eight bacteria isolated from the indoor environment: Staphylococcus capitis strain H36, S. capitis strain H65, S. cohnii strain H62, S. hominis strain H69, Microbacterium sp. strain H83, Mycobacterium iranicum strain H39, Plantibacter sp. strain H53, and Pseudomonas oryzihabitans strain H72

Author

Despoina S. Lymperopoulou,corresponding author1 David A. Coil,2 Denise Schichnes,3 Steven E. Lindow,1 Guillaume Jospin,2 Jonathan A. Eisen,2,4,5 and Rachel I. Adams1

Publish date

2017;


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