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3-Acetoxyflavone

$320

  • Brand : BIOFRON

  • Catalogue Number : BN-O1469

  • Specification : 98%(HPLC)

  • CAS number : 7578-68-9

  • Formula : C17H12O4

  • Molecular Weight : 280.27

  • PUBCHEM ID : 1666397

  • Volume : 20mg

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Catalogue Number

BN-O1469

Analysis Method

Specification

98%(HPLC)

Storage

2-8°C

Molecular Weight

280.27

Appearance

Botanical Source

Structure Type

Category

SMILES

CC(=O)OC1=C(OC2=CC=CC=C2C1=O)C3=CC=CC=C3

Synonyms

3-acetoxy-2-phenyl-chromen-4-one/3-Acetoxy-flavon/3-acetoxyflavonol/3-acetoxyflavone/4H-1-Benzopyran-4-one, 3-(acetyloxy)-2-phenyl-/4-Oxo-2-phenyl-4H-chromen-3-yl acetate/3-Acetoxy-2-phenyl-chromen-4-on

IUPAC Name

(4-oxo-2-phenylchromen-3-yl) acetate

Density

1.319g/cm3

Solubility

Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.

Flash Point

187.4±28.8 °C

Boiling Point

421.1±45.0 °C at 760 mmHg

Melting Point

InChl

InChl Key

NCHSTTAWIMAJHU-UHFFFAOYSA-N

WGK Germany

RID/ADR

HS Code Reference

Personal Projective Equipment

Correct Usage

For Reference Standard and R&D, Not for Human Use Directly.

Meta Tag

provides coniferyl ferulate(CAS#:7578-68-9) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of coniferyl ferulate are included as well.>> amp version: coniferyl ferulate

No Technical Documents Available For This Product.

PMID

31110211

Abstract

The clinical characteristics of adult spinal deformity (ASD) include worsening of deformity during gait, which leads to unstable posture and propensity to fall. The purpose of this study was to classify arm swing and to analyse its clinical implications. Clinical and radiographic evaluations were performed with 168 community-dwelling female volunteers recruited from a population register in Hokkaido, Japan, with a mean age of 67.3 ± 4.7 years, and arm swing was classified into four groups according to maximum forward and backward arm swing distance: (1) predominantly forward swing with forward swing always larger than backward swing (FS, n = 138), (2) equal or equivocal swing (ES, n = 8), (3) predominantly backward swing with backward swing always larger than forward swing (BS, n = 20), and (4) thigh-hand type without arm swing with their hands placed on thighs (TH, n = 2). BS and FS showed significant differences in radiographic lumbar lordosis (BS 19.4 ± 18.1° vs. FS 40.6 ± 14.5°, P < 0.01 ANOVA), pelvic tilt (BS 40.0 ± 7.3° vs. FS 22.9 ± 8.9°, p < 0.01), number of vertebral fractures (BS 1.2 ± 1.4 vs. FS 0.3 ± 0.6, p < 0.01), and trunk extensor muscle strength (BS 374.9 ± 134.8 N vs. FS 478.1 ± 172.6 N, p < 0.05). Arm swing correlated with severity of radiographic ASD, osteoporotic changes, and back muscle weakness. The number of ASD patients, which includes patients with de novo/idiopathic scoliosis, degenerative/osteoporotic kyphosis, and other neuromuscular deformities, has been increasing, and further study should clarify the importance of dynamic evaluation of ASD among elderly patients. Subject terms: Physical examination, Epidemiology

Title

Classification of arm swing as a clinical marker of advancing spinal deformity among community-dwelling female volunteers 60 years or older

Author

Tetsuya Kobayashi,corresponding author1 Shizuo Jimbo,1 Issei Senoo,1 Mutsuya Shimizu,1 Hiroshi Ito,1 and P. T. Hisashi Chiba2

Publish date

2019;

PMID

30213503

Abstract

This review summarizes the proceedings of a symposium presented at the “Alcoholism and Stress: A Framework for Future Treatment Strategies” conference held in Volterra, Italy on May 9-12, 2017. Psychiatric diseases, including alcohol use disorders (AUD), are influenced through complex interactions of genes, neurobiological pathways, and environmental influences. A better understanding of the common neurobiological mechanisms underlying an AUD necessitates an integrative approach, involving a systematic assessment of diverse species and phenotype measures. As part of the World Congress on Stress and Alcoholism, this symposium provided a detailed account of current strategies to identify mechanisms underlying the development and progression of AUD. Dr. Sean Farris discussed the integration and organization of transcriptome and postmortem human brain data to identify brain regional- and cell type-specific differences related to excessive alcohol consumption that are conserved across species. Dr. Brien Riley presented the results of a genomewide association study of DSM-IV alcohol dependence; although replication of genetic associations with alcohol phenotypes in humans remains challenging, model organism studies show that COL6A3, KLF12, and RYR3 affect behavioral responses to ethanol, and provide substantial evidence for their role in human alcohol-related traits. Dr. Rob Williams expanded upon the systematic characterization of extensive genetic-genomic resources for quantifying and clarifying phenotypes across species that are relevant to precision medicine in human disease. The symposium concluded with Dr. Robert Hitzemann’s description of transcriptome studies in a mouse model selectively bred for high alcohol (“binge-like”) consumption and a non-human primate model of long-term alcohol consumption. Together, the different components of this session provided an overview of systems-based approaches that are pioneering the experimental prioritization and validation of novel genes and gene networks linked with a range of behavioral phenotypes associated with stress and AUD.

KEYWORDS

alcohol use disorder, species conservation, co-expression networks, systems biology, RNA-seq, genome wide association study, recombinant inbred mice, transcriptome

Title

Cross-species molecular dissection across alcohol behavioral domains

Author

Sean P. Farris, Brien P. Riley, Robert W. Williams, Megan K. Mulligan, Michael J. Miles, Marcelo F. Lopez, Robert Hitzemann, Ovidiu D. Iancu, Alexander Colville, Nicole A.R. Walter, Priscila Darakjian, Denesa L. Oberbeck, James B. Daunais, Christina L. Zheng, Robert P. Searles, Shannon K. McWeeney, Kathleen A. Grant, R. Dayne Mayfield

Publish date

2018 Dec 28.

PMID

25183116

Abstract

Objective
To collect, preserve and document primary ethnopharmacological information on common natural remedies (NRs) used by the Chinese community to treat and/or manage common diseases in Mauritius, a tropical multicultural island in the Indian Ocean.

Methods
Face-to-face interviews were carried out with 52 key Chinese informants using a semi-structured questionnaire. Quantitative ethnobotanical indices, namely, the informant consensus factor (FIC), the use value, the fidelity level, the index of agreement on remedies and the relative importance were calculated.

Results
Plants (61) and animal species (17), belonging to 43 and 9 families respectively, constituted the exploited flora and fauna by the Chinese community. Based on the FIC the main categories of plants used were employed against injury and poisons due to external causes (FIC=0.97), diseases of the respiratory system (FIC=0.96), diseases of the eye and adnexa (FIC=0.95), undefined pains or illness (FIC=0.95), diseases during the postpartum period, diseases of the digestive system and diseases of the skin and subcutaneous tissue (FIC=0.94 each). For zootherapy, diseases of the circulatory system, diseases of the eye and adnexa, diseases of the skin and subcutaneous tissue and endocrine, nutritional and metabolic diseases had total consensus (FIC=1.00).

Conclusions
It was found that the Chinese community of Mauritius still relies, to a great extent, on NRs which need to be preserved and used sustainably. Nonetheless, further research is needed to probe the possible active constituents that could be the basis of an evidence-based investigation to discover new drugs.

KEYWORDS

Traditional Chinese medicine, Natural remedies, Ethnopharmacology, Herbal remedies, Zootherapy, Mauritius

Title

An ethnopharmacological survey of natural remedies used by the Chinese community in Mauritius

Author

Mohamad Fawzi Mahomoodally, Luviksha Drushilla Muthoorah

Publish date

2014 May;


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