Trichosanthes kirilowii Maxim./Cucumis melo var. inodorus (melon) and Trichosanthes kirilowii
[(2R,4aS,6aS,7S,8aR,10R,12aS,14aS,14bR)-10-(Benzoyloxy)-7-hydroxy-2,4a,6a,9,9,12a,14a-heptamethyl-1,2,3,4,4a,5,6,6a,7,8,8a,9,10,11,12,12a,13,14,14a,14b-icosahydro-2-picenyl]methyl benzoate/3,6-Picenediol, 11-[(benzoyloxy)methyl]-1,2,3,4,4a,5,6,6b,7,8,8a,9,10,11,12,12a,12b,13,14,14b-eicosahydro-4,4,6b,8a,11,12b,14b-heptamethyl-, 3-benzoate, (3R,4aR,6S,6bS,8aS,11R,12aR,12bS,14bS)-
3,29-Dibenzoyl rarounitriol is one major bioactive compound of multiflorane triterpene esters Trichosanthes kirilowii, can be chosen as the marker for quantitation of Trichosanthes kirilowii.
Methanol; Ethyl Acetate; Dichloromethane
706.5±60.0 °C at 760 mmHg
HS Code Reference
Personal Projective Equipment
For Reference Standard and R&D, Not for Human Use Directly.
provides coniferyl ferulate(CAS#:873001-54-8) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of coniferyl ferulate are included as well.>> amp version: coniferyl ferulate
A rapid, sensitive and high-throughput liquid chromatography-tandem mass spectrometry was established and validated to assay the concentrations of 3,29-dibenzoyl rarounitriol in rat plasma. Plasma samples were processed by liquid-liquid extraction with ethyl acetate and separated on a Hypersil Gold C18 column (50 × 4.6 mm, 3 µm) at an isocratic flow rate of 0.5 mL/min using methanol-10 mm ammonium acetate-formic acid (90:10:0.1, v/v/v) as mobile phase. The total run time was 5 min for each sample. MS/MS detection was accomplished in selected reaction monitoring mode with positive electrospray ionization. The calibration curve was linear over the concentration range of 0.125-50 ng/mL with lower limit of quantification of 0.125 ng/mL. The intra- and inter-day precisions were <10.1% in terms of coefficient of variation, and the accuracy was within ±11.7% in terms of relative error. The developed method was successfully applied to a pharmacokinetic study of 3,29-dibenzoyl rarounitriol following intragastric administration of 3.65 mg/kg to Wistar rats. Copyright © 2015 John Wiley & Sons, Ltd.
3,29-dibenzoyl rarounitriol; Trichosanthes kirilowii; multiflorane triterpene esters; pharmacokinetics; rat plasma
A rapid and sensitive LC-MS/MS method for quantification of 3,29-dibenzoyl rarounitriol in rat plasma: application to a pharmacokinetic study.
Zhao C1,2, Zhang N3, Chen B2, Song Y2, Zhu N2, Zhao L2, Liu C4, Meng X1.
To study the different mature stages and the best processing methods on the quality of Trichosanthes kirilowii seeds.
The content of 3,29-dibenzoyl rarounitriol in Trichosanthes kirilowii seeds was determined by HPLC. The sample of different mature stages such as immature, near mature and fully mature and processed by different methods were studied.
Fully mature Trichosanthes kirilowii seeds were better than the immatured, and the best processing method was dried under 60degrees C, the content of 3,29-dibenzoyl rarounitriol reached up to 131.63microlg/mL.
Different processing methods and different mature stages had a significant influence on the quality of Trichosanthes kirilowii seeds.
[Influence of different processing methods and mature stages on 3,29-dibenzoyl rarounitriol of Trichosanthes kirilowii seeds].
Liu JN, Xie XL, Yang TX, Zhang CL, Jia DS, Liu M, Wen CX.