13-Hydroxy-14-isopropylpodocarpa-8,11,13-trien-16-oic acid/1-Phenanthrenecarboxylic acid, 1,2,3,4,4a,9,10,10a-octahydro-7-hydroxy-1,4a-dimethyl-8-(1-methylethyl)-, (1S,4aS,10aR)-
Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
449.1±45.0 °C at 760 mmHg
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Personal Projective Equipment
For Reference Standard and R&D, Not for Human Use Directly.
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Background: A 35?year?old postpartum woman presented with myocardial infarction (MI) due to spontaneous coronary artery dissection (SCAD). In addition to conventional medical therapy, she was treated with immunosuppressive agents (prednisone and cytoxan) because of five noncontiguous coronary dissections, surgical inoperability, and postinfarction angina. Repeat angiography 94 days later demonstrated angiographically normal vessels.
Methods: A literature review of 42 additional cases of peripartum SCAD was performed, and the results were compared with this patient.
Results: Mortality was 48.8% (21/43). Sudden cardiac death was the initial presentation in 27.9% (12/43) of cases. The left coronary artery was involved in 78.6% (44/56) of dissections with left main segment dissection in 10 cases. In women who survived > 24 h post infarction, recurrent MI, usually due to a second coronary dissection, occurred in 20.8% (5/24). Histopathologic studies have often shown periadventitial inflammation (80%, 16/20), in which eosinophils predominate (68.8%, 11/16), and may be linked to the medial degeneration often found in these cases.
Conclusions: The common observation of eosinophilic periadventitial inflammation suggests a role in the pathophysiology of this rare, yet serious condition. Aggressive immunosuppressive therapy in this case of multivessel dissection resulted in spontaneous angiographic healing of all lesions.
coronary artery dissection, inflammation, pregnancy, myocardial infarction
Immunosuppressive therapy for peripartum?type spontaneous coronary artery dissection: Case report and review
Patrick T. Kolle, M.D.,corresponding author 1 , 2 Charles M. Cliffe, M.D., 1 , 2 and David J. Ridley, M.D. 1 , 2
Sera from both human cytomegalovirus (HCMV)-seropositive adults and infants with congenital HCMV infection recognized two major HCMV glycoprotein complexes. However, proliferative responses of peripheral blood mononuclear cells to these complexes varied among seropositive adults and were not detected in any of the infants. Thus, these glycoproteins alone may not be sufficient to develop a subviral HCMV vaccine.
Human immune responses to major human cytomegalovirus glycoprotein complexes.
Y N Liu, B Kari, and R C Gehrz
Non-destructive tools for the in situ evaluation of vine fruit quality and vineyard management can improve the market value of table grape. We proposed a new approach based on a portable fluorescence sensor to map the ripening level of Crimson Seedless table grape in five different plots in the East, Central-North and South of the Macedonia Region of Greece. The sensor provided indices of ripening and color such as SFRR and ANTHRG correlated to the chlorophyll and anthocyanin berry contents, respectively. The mean ANTHRG index was significantly different among all the plots examined due to the occurrence of different environmental conditions and/or asynchronous ripening processes. The indices presented moderate, poor in some cases, spatial variability, probably due to a significant vine-to-vine, intra-vine and intra-bunch variability. The cluster analysis was applied to the plot with the most evident spatial structure (at Kilkis). Krigged maps of the SFRR, ANTHRG and yield were classified by k-means clustering in two-zones that differed significantly in their mean values. ANTHRG and SFRR were inversely correlated over 64% of the plot. SFRR appeared to be a potential useful proxy of yield since it was directly correlated to yield over 66% of the plot. The grape color (ANTHRG) was slightly higher over the low-yield zones with respect to the high-yield zones. Our study showed that the combination of anthocyanins and chlorophyll indices detected in the field on Crimson Seedless table grape by a portable fluorescence sensor can help in defining the best harvest time and the best areas for harvesting.
anthocyanin mapping, chlorophyll mapping, Crimson Seedless, fluorescence, precision viticulture, optical sensors, table grape, zoning
Fluorescence-Sensor Mapping for the in Vineyard Non-Destructive Assessment of Crimson Seedless Table Grape Quality
Lorenza Tuccio,1,† Lucia Cavigli,1,† Francesca Rossi,1 Olga Dichala,2 Fotis Katsogiannos,2 Ilias Kalfas,2 and Giovanni Agati1,*