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4-Amino-2,5-dimethoxy-N-phenylbenzenesulphonamide

$125

  • Brand : BIOFRON

  • Catalogue Number : BN-O1053

  • Specification : 99%(HPLC)

  • CAS number : 52298-44-9

  • Formula : C14H16N2O4S

  • Molecular Weight : 308.35

  • PUBCHEM ID : 104143

  • Volume : 5mg

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Catalogue Number

BN-O1053

Analysis Method

Specification

99%(HPLC)

Storage

2-8°C

Molecular Weight

308.35

Appearance

Botanical Source

Structure Type

Category

SMILES

COC1=CC(=C(C=C1N)OC)S(=O)(=O)NC2=CC=CC=C2

Synonyms

4-Amino-2,5-dimethoxy-N-phenylsulfonamide/2,5-Dimethoxy-N'-phenylsulfanilamide/4-Amino-2,5-dimethoxybenzenesulfonanilide/4-Amino-2,5-dimethoxy-N-phenylbenzenesulfonamide

IUPAC Name

4-amino-2,5-dimethoxy-N-phenylbenzenesulfonamide

Density

1.347 g/cm3

Solubility

Flash Point

268.4ºC

Boiling Point

520.1ºC at 760 mmHg

Melting Point

186 °C

InChl

InChl Key

NFYQAEPHDGXJSY-UHFFFAOYSA-N

WGK Germany

RID/ADR

HS Code Reference

Personal Projective Equipment

Correct Usage

For Reference Standard and R&D, Not for Human Use Directly.

Meta Tag

provides coniferyl ferulate(CAS#:52298-44-9) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of coniferyl ferulate are included as well.>> amp version: coniferyl ferulate

No Technical Documents Available For This Product.

PMID

25621000

Abstract

Background
In Ethiopia national breastfeeding practice is poor because of traditional and cultural beliefs, low educational levels, heavy workload of mothers, poor sanitary conditions, type of assistance at delivery, duration of stay at home, ethnicity, poor maternal knowledge, age, parity, antenatal service utilization and place of delivery. This study is aimed to assess the prevalence and determinants of exclusive breastfeeding practice in mothers in Enderta woreda (district), Ethiopia.

Methods
A community based cross-sectional study with multistage sampling method was used to select 541 mothers with children less than 24 months of age in Enderta woreda. Data was collected by administered structured questionnaire. Bivariate and Multivariable logistic regression was used to check the associations and controlling confounding variables.

Result
A total of 530 mothers were included with a response rate 98%. The mean (± SD) age of the mothers was 26.9 (± 5.98) years. Majority of the mothers (70.2%) were practiced exclusive breastfeeding. Age of the mother (AOR 0.12; 95% CI: 0.02, 0.97), age of the child (AOR 0.52 95% CI: 0.27, 0.99) and postnatal care (AOR; 2.68; 95% CI: 1.44, 4.98) were found statistically significant with exclusive breastfeeding.

Conclusion
The prevalence rate of exclusive breastfeeding was high in Enderta woreda. The age of the mother, age of the child and receiving postnatal care were the determinant factors for exclusive breastfeeding in the study area.

KEYWORDS

Exclusive breastfeeding, Tigray, Ethiopia

Title

Prevalence and determinant factors of exclusive breastfeeding practices among mothers in Enderta woreda, Tigray, North Ethiopia: a cross-sectional study

Author

Bahre Teka, Huruy Assefa,corresponding author and Kiday Haileslassie

Publish date

2015

PMID

26452470

Abstract

Background
The capacity of European pear fruit (Pyrus communis L.) to ripen after harvest develops during the final stages of growth on the tree. The objective of this study was to characterize changes in ‘Bartlett’ pear fruit physico-chemical properties and transcription profiles during fruit maturation leading to attainment of ripening capacity.

Results
The softening response of pear fruit held for 14 days at 20 °C after harvest depended on their maturity. We identified four maturity stages: S1-failed to soften and S2- displayed partial softening (with or without ET-ethylene treatment); S3 – able to soften following ET; and S4 – able to soften without ET. Illumina sequencing and Trinity assembly generated 68,010 unigenes (mean length of 911 bp), of which 32.8 % were annotated to the RefSeq plant database. Higher numbers of differentially expressed transcripts were recorded in the S3-S4 and S1-S2 transitions (2805 and 2505 unigenes, respectively) than in the S2-S3 transition (2037 unigenes). High expression of genes putatively encoding pectin degradation enzymes in the S1-S2 transition suggests pectic oligomers may be involved as early signals triggering the transition to responsiveness to ethylene in pear fruit. Moreover, the co-expression of these genes with Exps (Expansins) suggests their collaboration in modifying cell wall polysaccharide networks that are required for fruit growth. K-means cluster analysis revealed that auxin signaling associated transcripts were enriched in cluster K6 that showed the highest gene expression at S3. AP2/EREBP (APETALA 2/ethylene response element binding protein) and bHLH (basic helix-loop-helix) transcripts were enriched in all three transition S1-S2, S2-S3, and S3-S4. Several members of Aux/IAA (Auxin/indole-3-acetic acid), ARF (Auxin response factors), and WRKY appeared to play an important role in orchestrating the S2-S3 transition.

Conclusions
We identified maturity stages associated with the development of ripening capacity in ‘Bartlett’ pear, and described the transcription profile of fruit at these stages. Our findings suggest that auxin is essential in regulating the transition of pear fruit from being ethylene-unresponsive (S2) to ethylene-responsive (S3), resulting in fruit softening. The transcriptome will be helpful for future studies about specific developmental pathways regulating the transition to ripening.

Electronic supplementary material
The online version of this article (doi:10.1186/s12864-015-1939-9) contains supplementary material, which is available to authorized users.

KEYWORDS

RNA-Seq, EBSeq, Cell wall, Auxin, Ethylene, bZIP, AP2/EREBP, bHLH, WRKY, Aux/IAA

Title

A transcriptome approach towards understanding the development of ripening capacity in ‘Bartlett’ pears (Pyrus communis L.)

Author

Ngoc T. Nham,corresponding author Sergio Tonetto de Freitas, Andrew J. Macnish, Kevin M. Carr, Trisha Kietikul, Angelo J. Guilatco, Cai-Zhong Jiang, Florence Zakharov, and Elizabeth J Mitchamcorresponding author

Publish date

2015

PMID

30768591

Abstract

In the U.S., more than 80% of African-American smokers use mentholated cigarettes, compared to less than 30% of Caucasian smokers. The reasons for these differences are not well understood. To determine if genetic variation contributes to mentholated cigarette smoking, we performed an exome-wide association analysis in a multiethnic population-based sample from Dallas, TX (N = 561). Findings were replicated in an independent cohort of African Americans from Washington, DC (N = 741). We identified a haplotype of MRGPRX4 (composed of rs7102322[G], encoding N245S, and rs61733596[G], T43T), that was associated with a 5-to-8 fold increase in the odds of menthol cigarette smoking. The variants are present solely in persons of African ancestry. Functional studies indicated that the variant G protein-coupled receptor encoded by MRGPRX4 displays reduced agonism in both arrestin-based and G protein-based assays, and alteration of agonism by menthol. These data indicate that genetic variation in MRGPRX4 contributes to inter-individual and inter-ethnic differences in the preference for mentholated cigarettes, and that the existence of genetic factors predisposing vulnerable populations to mentholated cigarette smoking can inform tobacco control and public health policies.

Title

An African-specific haplotype in MRGPRX4 is associated with menthol cigarette smoking

Author

Julia Kozlitina, Conceptualization, Formal analysis, Investigation, Methodology, Project administration, Supervision, Visualization, Writing - original draft, Writing - review & editing,#1 Davide Risso, Formal analysis, Investigation, Methodology, Visualization, Writing - original draft, Writing - review & editing,#2 Katherine Lansu, Formal analysis, Investigation, Methodology, Visualization, Writing - original draft, Writing - review & editing,3 Reid Hans Johnson Olsen, Investigation, Visualization,3 Eduardo Sainz, Investigation, Methodology, Writing - original draft,2 Donata Luiselli, Investigation, Methodology, Project administration,4 Arnab Barik, Investigation,5 Carlos Frigerio-Domingues, Investigation,2 Luca Pagani, Formal analysis, Investigation, Methodology, Visualization, Writing - original draft, Writing - review & editing,6,¤a Stephen Wooding, Conceptualization, Funding acquisition, Investigation, Methodology, Writing - original draft,7 Thomas Kirchner, Data curation, Investigation, Resources,8,¤b Ray Niaura, Investigation, Resources,8,¤b Bryan Roth, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Resources, Supervision, Writing - original draft,3 and Dennis Drayna, Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Project administration, Resources, Supervision, Writing - original draft, Writing - review & editing2,*

Publish date

2019 Feb;


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