Catalogue Number
BF-H3020
Analysis Method
HPLC,NMR,MS
Specification
98%
Storage
2-8°C
Molecular Weight
154.16
Appearance
White powder
Botanical Source
Gastrodia elata
Structure Type
Phenolics
Category
Standards;Natural Pytochemical;API
SMILES
COC1=C(C=CC(=C1)CO)O
Synonyms
4-Hydroxy-3-methoxybenzyl alcohol/Vanillyl alcohol/Benzenemethanol, 4-hydroxy-3-methoxy-/4-(Hydroxymethyl)-2-methoxyphenol
IUPAC Name
4-(hydroxymethyl)-2-methoxyphenol
Density
1.2±0.1 g/cm3
Solubility
Methanol
Flash Point
143.2±23.7 °C
Boiling Point
313.1±27.0 °C at 760 mmHg
Melting Point
110-117 °C(lit.)
InChl
InChl Key
WGK Germany
RID/ADR
HS Code Reference
2909500000
Personal Projective Equipment
Correct Usage
For Reference Standard and R&D, Not for Human Use Directly.
Meta Tag
provides coniferyl ferulate(CAS#:498-00-0) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of coniferyl ferulate are included as well.>> amp version: coniferyl ferulate
MSDS
21705974
Gastrodia elata Blume (GE) has long been used in oriental countries as a traditional herbal medicine to relieve symptoms associated with neurological ailments such as vertigo, general paralysis and epilepsy. In this study, we have investigated the effects of GE extracts and its major bioactive components on 1-methyl-4-phenylpyridinium (MPP+)-treated MN9D dopaminergic cells, a classic in vitro model for Parkinson’s disease (PD). We found that vanillyl alcohol effectively inhibited the cytotoxicity and improved cell viability in MPP+-induced MN9D dopaminergic cells. The underlying mechanisms of vanillyl alcohol action were also studied. Vanillyl alcohol attenuated the elevation of reactive oxygen species (ROS) levels, decreased in the Bax/Bcl-2 ratio and poly (ADP-ribose) polymerase proteolysis. These results indicate that vanillyl alcohol protected dopaminergic MN9D cells against MPP+-induced apoptosis by relieving oxidative stress and modulating the apoptotic process and is therefore a potential candidate for treatment of neurodegenerative diseases such as Parkinson’s disease.
Neuroprotective effects of vanillyl alcohol in Gastrodia elata Blume through suppression of oxidative stress and anti-apoptotic activity in toxin-induced dopaminergic MN9D cells.
Kim IS1, Choi DK, Jung HJ.
2011 Jun 24
18958417
Vanillyl alcohol displayed a significant inhibition in the chick chorioallantoic membrane (CAM) angiogenesis. Vanillyl alcohol was also shown to contain anti-inflammatory activity using acetic acid-induced permeability and carrageenan-induced air pouch models in mice. Anti-nociceptive activity of vanillyl alcohol was also assessed using acetic acid-induced writhing test in mice. Taken together, vanillyl alcohol possesses anti-angiogenic, anti-inflammatory, and anti-nociceptive activities, which may be partly responsible for pharmacological efficacies of several folkloric medicines containing vanillyl alcohol.
Anti-angiogenic, anti-inflammatory and anti-nociceptive activities of vanillyl alcohol.
Jung HJ1, Song YS, Lim CJ, Park EH.
2008 Oct
15844340
The electrooxidation of benzylic alcohol derivative in acidic aqueous solution shows an oxidation pre-peak in the cyclic voltammogram, which means that the reaction is proceeding via an ECE mechanism where the second electron transfer occurs at a less positive potential. From the result of the rotating ring-disk electrode voltammetry, the initial oxidation response of the electrode reaction can be extracted.
Electrooxidation of vanillyl alcohol in acidic aqueous solution using rotating ring-disk electrode voltammetry.
Kishioka SY1, Yamada A.
2005 Apr
Description :
Vanillyl alcohol (Vanillic alcohol), derived from vanillin, is a phenolic alcohol and is used as a flavoring agent in foods and beverages[1].