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5-Acetoxy-7-hydroxyflavone

$1,120

  • Brand : BIOFRON

  • Catalogue Number : BN-O1549

  • Specification : 98%(HPLC)

  • CAS number : 132351-58-7

  • Formula : C17H12O5

  • Molecular Weight : 296.3

  • PUBCHEM ID : 15731440

  • Volume : 5mg

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Catalogue Number

BN-O1549

Analysis Method

Specification

98%(HPLC)

Storage

-20℃

Molecular Weight

296.3

Appearance

Yellow powder

Botanical Source

This product is isolated and purified from the heartwoods of Pinus armandii.

Structure Type

Category

SMILES

CC(=O)OC1=CC(=CC2=C1C(=O)C=C(O2)C3=CC=CC=C3)O

Synonyms

5-O-acetylchrysin/5-Acetoxy-7-hydroxyflavone/5-acetoxy-7-hydroxychrysin/4H-1-Benzopyran-4-one, 5-(acetyloxy)-7-hydroxy-2-phenyl-/7-Hydroxy-4-oxo-2-phenyl-4H-chromen-5-yl acetate

IUPAC Name

Density

1.4±0.1 g/cm3

Solubility

Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.

Flash Point

202.4±23.6 °C

Boiling Point

534.9±50.0 °C at 760 mmHg

Melting Point

InChl

InChl Key

ZCEVJMPLRAGWNX-UHFFFAOYSA-N

WGK Germany

RID/ADR

HS Code Reference

Personal Projective Equipment

Correct Usage

For Reference Standard and R&D, Not for Human Use Directly.

Meta Tag

provides coniferyl ferulate(CAS#:132351-58-7) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of coniferyl ferulate are included as well.>> amp version: coniferyl ferulate

No Technical Documents Available For This Product.

PMID

29311112

Abstract

Satellite DNAs are tandemly repeated sequences clustered within heterochromatin. However, in some cases, such as the major TCAST1 satellite DNA from the beetle Tribolium castaneum, they are found partially dispersed within euchromatin. Such organization together with transcriptional activity enables TCAST1 to modulate the activity of neighboring genes. In order to explore if other T. castaneum repetitive families have features that could provide them with a possible gene-modulatory role, we compare here the structure, organization, dispersion profiles, and transcription activity of 10 distinct TCAST repetitive families including TCAST1. The genome organization of TCAST families exhibit either satellite-like or transposon-like characteristics. In addition to heterochromatin localization, bioinformatic searches of the assembled genome have revealed dispersion of all families within euchromatin, preferentially in the form of single repeats. Dispersed TCAST repeats are mutually correlated in distribution and are grouped in distinct regions of euchromatin. The repeats are associated with genes, are enriched in introns relative to intergenic regions, and very rarely overlap exons. In spite of the different mechanisms of repeat proliferation, such as transposition and homologous recombination, all TCAST families share a similar frequency of spreading as well as dispersion and gene association profiles. Additionally, TCAST families are transcribed and their transcription is significantly activated by heat stress. A possibility that such common features of TCAST families might be related to their potential gene-modulatory role is discussed.

KEYWORDS

satellite DNA, repetitive DNA, transcription, gene regulation, Tribolium castaneum

Title

Dispersion Profiles and Gene Associations of Repetitive DNAs in the Euchromatin of the Beetle Tribolium castaneum

Author

Josip Brajković,*,1 Željka Pezer,*,1 Branka Bruvo-Mađarić,* Antonio Sermek,* Isidoro Feliciello,*†,2 and Đurđica Ugarković*,2

Publish date

2018 Mar

PMID

17445658

Abstract

Objective
To examine the association of cigarette smoking with subsequent fatal prostate cancer.

Methods
Two private censuses were conducted in Washington County, Maryland, in which 26,810 adult men in 1963 and 28,292 in 1975 provided smoking information. Prostate cancer deaths through 2002 (1963 cohort: 240 deaths; 1975 cohort: 184) were ascertained by review of death certificates. Poisson regression was used to estimate the rate ratio (RR) of prostate cancer death adjusted for age.

Results
Overall, cigarette smokers in the 1963 census cohort were not more likely to die from prostate cancer than never smokers of cigarettes, pipes, and cigars when considering total follow-up. However, current smokers of 20+ cigarettes per day (RR = 2.38; 95% CI 0.94-5.99) and former smokers (RR = 2.75; 95% CI 1.13-6.74) had a higher risk of death from prostate cancer during the first 10 years of follow-up. Weaker positive associations of prostate cancer death with current and former cigarette smoking were seen during the first 10 years of follow-up in the 1975 census cohort. Current cigarette smoking at baseline was not associated with prostate cancer incidence.

Conclusion
The lack of an association of cigarette smoking with prostate cancer incidence, but the tendency of a higher prostate cancer mortality in former and current cigarette smokers earlier in follow-up is consistent with other studies in which smoking was assessed once at baseline.

Title

Smoking and risk of fatal prostate cancer in a prospective US study

Author

Sabine Rohrmann,a,b Jeanine M Genkinger,c Alyce Burke,a,d Kathy J Helzlsouer,a,d,e,f George W Comstock,a,d Anthony J Alberg,a,d,e and Elizabeth A Platza,e,g

Publish date

2010 Apr 13.


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