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5-Aminoindazole

$63

Brand : BIOFRON
Catalogue Number : BN-O1166
Specification : 98%(HPLC)
CAS number : 19335-11-6
Formula : C7H7N3
Molecular Weight : 133.15
PUBCHEM ID : 88012
Volume : 5mg

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Catalogue Number

BN-O1166

Analysis Method

Specification

98%(HPLC)

Storage

2-8°C

Molecular Weight

133.15

Appearance

Botanical Source

Structure Type

Category

SMILES

C1=CC2=C(C=C1N)C=NN2

Synonyms

IFLAB-BB F2108-0020/5-AMINOINDAZOLE/5-amino-1h-indazol/5-amino-1h-indazole/5-Amino (1H)indazole/indazol-5-ylamine/1H-indazol-5-yl amine/1H-Indazol-6-amine/1H-Indazol-5-amine/6-Amino-1H-indazole/1H-Indazole-5-amine/2H-Indazol-6-amine/5-indazolamine/5-Amino(1H)indazole

IUPAC Name

1H-indazol-5-amine

Density

1.4±0.1 g/cm3

Solubility

Flash Point

209.5±7.6 °C

Boiling Point

376.6±15.0 °C at 760 mmHg

Melting Point

175-178 °C(lit.)

InChl

InChl Key

XBTOSRUBOXQWBO-UHFFFAOYSA-N

WGK Germany

RID/ADR

HS Code Reference

Personal Projective Equipment

Correct Usage

For Reference Standard and R&D, Not for Human Use Directly.

Meta Tag

provides coniferyl ferulate(CAS#:19335-11-6) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of coniferyl ferulate are included as well.>> amp version: coniferyl ferulate

No Technical Documents Available For This Product.

PMID

20814822

Abstract

Six new series of pyrazolo[4,3-f]quinoline derivatives with potential bioactivities were synthesized by the three-component reactions of aromatic aldehydes, 5-aminoindazole, and various cyclic 1,3-dicarbonyl compounds under microwave irradiation. This protocol has the valuable features of structural diversity of products, broader substrate scope, operational simplicity, high yields, and short reaction time. Moreover, the structure of compound 88a was confirmed by an X-ray crystallographic analysis and attested to the chemoselectivity of reaction where 1-methyl barbituric acid participated.

Title

A Diversity-Oriented Synthesis of pyrazolo[4,3-f]quinoline Derivatives With Potential Bioactivities via Microwave-Assisted Multi-Component Reactions

Author

Feng Shi 1, Shu Zhang, Shan-Shan Wu, Yuan Gao, Shu-Jiang Tu

Publish date

2011 May

PMID

21078554

Abstract

Affinity reagents that target protein kinases are powerful tools for signal transduction research. Here, we describe a general set of kinase ligands based on a 5-aminoindazole scaffold. This scaffold can readily be derivatized with diverse binding elements and immobilized analogs allow selective enrichment of protein kinases from complex mixtures.

Title

Protein Kinase Affinity Reagents Based on a 5-aminoindazole Scaffold

Author

Ratika Krishnamurty 1, Amanda M Brock, Dustin J Maly

Publish date

2011 Jan 1

PMID

16827557

Abstract

A microwave-assisted parallel synthesis of 2,4-disubstituted 5-aminoimidazoles has been developed. Significant rate enhancement was observed for all steps in the three-step protocol. The overall reaction time was shortened to 25 min, as compared to 53 h for the conventional procedures. A representative set of 2,4-disubstituted 5-aminoimidazoles was prepared using commercially available parallel reactors.

Title

Synthesis of 2,4-disubstituted 5-aminoimidazoles Using Microwave Irradiation

Author

Chai Hoon Soh 1, Wai Keung Chui, Yulin Lam

Publish date

Jul-Aug 2006