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6-Hydroxyindole

$52

  • Brand : BIOFRON

  • Catalogue Number : BD-P0679

  • Specification : 98.0%(HPLC)

  • CAS number : 2380-86-1

  • PUBCHEM ID : 524508

  • Volume : 25mg

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Catalogue Number

BD-P0679

Analysis Method

HPLC,NMR,MS

Specification

98.0%(HPLC)

Storage

2-8°C

Molecular Weight

Appearance

Off-white crystal

Botanical Source

Structure Type

Indoles

Category

Standards;Natural Pytochemical;API

SMILES

C1=CC(=CC2=C1C=CN2)O

Synonyms

indolol/6-hydroxy-1h-indole/1H-Indol-6-ol/6-Hydroxyindole/indol-6-ol/6-monohydroxyindole/6-hydroxy-indole/6-indolol

IUPAC Name

1H-indol-6-ol

Applications

Density

1.3±0.1 g/cm3

Solubility

Flash Point

161.4±20.4 °C

Boiling Point

343.2±15.0 °C at 760 mmHg

Melting Point

124-130 °C

InChl

InChl Key

WGK Germany

RID/ADR

HS Code Reference

2933990000

Personal Projective Equipment

Correct Usage

For Reference Standard and R&D, Not for Human Use Directly.

Meta Tag

provides coniferyl ferulate(CAS#:2380-86-1) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of coniferyl ferulate are included as well.>> amp version: coniferyl ferulate

No Technical Documents Available For This Product.

PMID

31460758

Abstract

An efficient gold-catalyzed formation of 6-hydroxyindoles from substituted alkynylcyclohexadienones and amines have been developed. In this reaction two new C-N bonds were formed, and moderate to very good yields of the 6-hydroxyindole derivatives were obtained in one pot. This organic transformation tolerates a range of substituted alkynylcyclohexadienones and amines, which resulted in 6-hydroxyindole derivatives selectively.

Title

Gold-Catalyzed Synthesis of 6-Hydroxyindoles From Alkynylcyclohexadienones and Substituted Amines

Author

Veerabhushanam Kadiyala 1 , Perla Bharath Kumar 1 , Sridhar Balasubramanian 2 , Galla V Karunakar 1

Publish date

2019 Sep 20

PMID

25297906

Abstract

The Cosmetic Ingredient Review Expert Panel (Panel) reviewed the safety of 6-hydroxyindole, which functions as an oxidative hair dye ingredient. The Panel considered relevant animal and human data provided in this safety assessment and concluded that 6-hydroxyindole is safe for use in oxidative hair dye formulations.

Title

Safety Assessment of 6-hydroxyindole as Used in Cosmetics

Author

Christina L Burnett 1 , Bart Heldreth 2 , Wilma F Bergfeld 3 , Donald V Belsito 3 , Ronald A Hill 3 , Curtis D Klaassen 3 , Daniel C Liebler 3 , James G Marks Jr 3 , Ronald C Shank 3 , Thomas J Slaga 3 , Paul W Snyder 3 , F Alan Andersen 4

Publish date

Sep-Oct 2014

PMID

22932912

Abstract

Based on 6-hydroxyindole BODIPY with a Schiff-base structure, NIR fluorescence with impressively high selectivity is triggered by deprotonation of the phenol group upon binding with Zn(2+) due to the chelation-enhanced fluorescence effect, thus realizing a promising application in bioimaging of Zn(2+).

Title

Target-triggered Deprotonation of 6-hydroxyindole-based BODIPY: Specially Switch on NIR Fluorescence Upon Selectively Binding to Zn2+

Author

Jian Cao 1 , Chunchang Zhao, Xuzhe Wang, Yanfen Zhang, Weihong Zhu

Publish date

2012 Oct 11