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6-Methoxyspirotryprostatin B

$1,440

  • Brand : BIOFRON

  • Catalogue Number : BN-O0917

  • Specification : 97%(HPLC)

  • CAS number : 1031727-28-2

  • Formula : C22H23N3O4

  • Molecular Weight : 393.44

  • Volume : 5mg

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Catalogue Number

BN-O0917

Analysis Method

Specification

97%(HPLC)

Storage

2-8°C

Molecular Weight

393.44

Appearance

Botanical Source

Structure Type

Category

SMILES

C1=CC=C(C(=C1)C(C#N)NC2=CC=CC=C2NC(C#N)C3=CC=CC=C3O)O

Synonyms

2-[2-[[cyano-(2-hydroxyphenyl)methyl]amino]anilino]-2-(2-hydroxyphenyl)acetonitrile

IUPAC Name

Density

Solubility

Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.

Flash Point

Boiling Point

Melting Point

InChl

InChl Key

WGK Germany

RID/ADR

HS Code Reference

Personal Projective Equipment

Correct Usage

For Reference Standard and R&D, Not for Human Use Directly.

Meta Tag

provides coniferyl ferulate(CAS#:1031727-28-2) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of coniferyl ferulate are included as well.>> amp version: coniferyl ferulate

No Technical Documents Available For This Product.

PMID

29649290

Abstract

Objectives
We aimed to describe ethnic variations in infant mortality and explore the contribution of area deprivation, mother’s country of birth, and prematurity to these variations.

Methods
We analyzed routine birth and death data on singleton live births (gestational age≥22 weeks) in England and Wales, 2006-2012. Infant mortality by ethnic group was analyzed using logistic regression with adjustment for sociodemographic characteristics and gestational age.

Results
In the 4,634,932 births analyzed, crude infant mortality rates were higher in Pakistani, Black Caribbean, Black African, and Bangladeshi infants (6.92, 6.00, 5.17 and 4.40 per 1,000 live births, respectively vs. 2.87 in White British infants). Adjustment for maternal sociodemographic characteristics changed the results little. Further adjustment for gestational age strongly attenuated the risk in Black Caribbean (OR 1.02, 95% CI 0.89-1.17) and Black African infants (1.17, 1.06-1.29) but not in Pakistani (2.32, 2.15-2.50), Bangladeshi (1.47, 1.28-1.69), and Indian infants (1.24, 1.11-1.38). Ethnic variations in infant mortality differed significantly between term and preterm infants. At term, South Asian groups had higher risks which cannot be explained by sociodemographic characteristics. In preterm infants, adjustment for degree of prematurity (<28, 28-31, 32-33, 34-36 weeks) fully explained increased risks in Black but not Pakistani and Bangladeshi infants. Sensitivity analyses with further adjustment for small for gestational age, or excluding deaths due to congenital anomalies did not fully explain the excess risk in South Asian groups. Conclusions Higher infant mortality in South Asian and Black infants does not appear to be explained by sociodemographic characteristics. Higher proportions of very premature infants appear to explain increased risks in Black infants but not in South Asian groups. Strategies targeting the prevention and management of preterm birth in Black groups and suboptimal birthweight and modifiable risk factors for congenital anomalies in South Asian groups might help reduce ethnic inequalities in infant mortality.

Title

The contribution of gestational age, area deprivation and mother’s country of birth to ethnic variations in infant mortality in England and Wales: A national cohort study using routinely collected data

Author

Yangmei Li, Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Project administration, Visualization, Writing - original draft, Writing - review & editing,1,* Maria A. Quigley, Conceptualization, Funding acquisition, Writing - review & editing,1 Nirupa Dattani, Funding acquisition, Writing - review & editing,2 Ron Gray, Funding acquisition, Writing - review & editing,1 Hiranthi Jayaweera, Funding acquisition, Writing - review & editing,3 Jennifer J. Kurinczuk, Funding acquisition, Writing - review & editing,1 Alison Macfarlane, Funding acquisition, Writing - review & editing,2 and Jennifer Hollowell, Conceptualization, Data curation, Funding acquisition, Methodology, Supervision, Writing - original draft, Writing - review & editing1

Publish date

2018


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