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[8]-Shogaol

$1,120

  • Brand : BIOFRON

  • Catalogue Number : BD-P0802

  • Specification : 98.0%(HPLC&TLC)

  • CAS number : 36700-45-5

  • Formula : C19H28O3

  • Molecular Weight : 304.42

  • PUBCHEM ID : 6442560

  • Volume : 50mg

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Catalogue Number

BD-P0802

Analysis Method

HPLC,NMR,MS

Specification

98.0%(HPLC&TLC)

Storage

-20℃

Molecular Weight

304.42

Appearance

Pale yellow liquid

Botanical Source

Zingiber officinale Roscoe/Ginger

Structure Type

Phenols

Category

Standards;Natural Pytochemical;API

SMILES

CCCCCCCC=CC(=O)CCC1=CC(=C(C=C1)O)OC

Synonyms

4-Dodecen-3-one, 1-(4-hydroxy-3-methoxyphenyl)-, (4E)-/(4E)-1-(4-hydroxy-3-methoxyphenyl)dodec-4-en-3-one/8-Shogaol/(4E)-1-(4-Hydroxy-3-methoxyphenyl)-4-dodecen-3-one

IUPAC Name

(E)-1-(4-hydroxy-3-methoxyphenyl)dodec-4-en-3-one

Applications

[8]-Shogaol, one of the pungent phenolic compounds in ginger, exhibits anti-platelet activity (IC50=5 μM) and inhibits COX-2 (IC50=17.5 μM). [8]-Shogaol induces apoptosis in human leukemia cells[1][2][3][4].

Density

1.0±0.1 g/cm3

Solubility

Methanol; Acetontrile; DMSO

Flash Point

154.6±19.4 °C

Boiling Point

452.3±35.0 °C at 760 mmHg

Melting Point

InChl

InChI=1S/C19H28O3/c1-3-4-5-6-7-8-9-10-17(20)13-11-16-12-14-18(21)19(15-16)22-2/h9-10,12,14-15,21H,3-8,11,13H2,1-2H3/b10-9+

InChl Key

LGZSMXJRMTYABD-MDZDMXLPSA-N

WGK Germany

RID/ADR

HS Code Reference

2938900000

Personal Projective Equipment

Correct Usage

For Reference Standard and R&D, Not for Human Use Directly.

Meta Tag

provides coniferyl ferulate(CAS#:36700-45-5) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of coniferyl ferulate are included as well.>> amp version: coniferyl ferulate

No Technical Documents Available For This Product.

PMID

27322227

Abstract

The effects of different drying methods (freeze drying, vacuum oven drying, and shade drying) on the phytochemical constituents associated with the antioxidant activities of Z. officinale var. rubrum Theilade were evaluated to determine the optimal drying process for these rhizomes. Total flavonoid content (TFC), total phenolic content (TPC), and polyphenol oxidase (PPO) activity were measured using the spectrophotometric method. Individual phenolic acids and flavonoids, 6- and 8-gingerol and shogaol were identified by ultra-high performance liquid chromatography method. Ferric reducing antioxidant potential (FRAP) and 1,1-diphenyl-2-picrylhydrazyl (DPPH) assays were used for the evaluation of antioxidant activities. The highest reduction in moisture content was observed after freeze drying (82.97%), followed by vacuum oven drying (80.43%) and shade drying (72.65%). The highest TPC, TFC, and 6- and 8-shogaol contents were observed in samples dried by the vacuum oven drying method compared to other drying methods. The highest content of 6- and 8-gingerol was observed after freeze drying, followed by vacuum oven drying and shade drying methods. Fresh samples had the highest PPO activity and lowest content of flavonoid and phenolic acid compounds compared to dried samples. Rhizomes dried by the vacuum oven drying method represent the highest DPPH (52.9%) and FRAP activities (566.5 μM of Fe (II)/g DM), followed by freeze drying (48.3% and 527.1 μM of Fe (II)/g DM, respectively) and shade drying methods (37.64% and 471.8 μM of Fe (II)/g DM, respectively) with IC50 values of 27.2, 29.1, and 34.8 μg/mL, respectively. Negative and significant correlations were observed between PPO and antioxidant activity of rhizomes. Vacuum oven dried rhizomes can be utilized as an ingredient for the development of value-added food products as they contain high contents of phytochemicals with valuable antioxidant potential.

KEYWORDS

Zingiber officinale var. rubrum Theilade, storage, phytochemicals, polyphenol oxidase, DPPH activity, FRAP activity

Title

Variation of the Phytochemical Constituents and Antioxidant Activities of Zingiber officinale var. rubrum Theilade Associated with Different Drying Methods and Polyphenol Oxidase Activity

Author

Ali Ghasemzadeh,1,* Hawa Z. E. Jaafar,1 and Asmah Rahmat2

Publish date

2016 Jun