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AcetylResveratrol

$54

  • Brand : BIOFRON

  • Catalogue Number : AV-H25056

  • Specification : 98%

  • CAS number : 42206-94-0

  • Formula : C20H18O6

  • Molecular Weight : 354.35

  • PUBCHEM ID : 5962587

  • Volume : 20mg

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Catalogue Number

AV-H25056

Analysis Method

HPLC,NMR,MS

Specification

98%

Storage

2-8°C

Molecular Weight

354.35

Appearance

Off-white powder

Botanical Source

Polygonum cuspidatum sieb.et zucc.; Vitis vinifera L.

Structure Type

Stilbenes

Category

Standards;Natural Pytochemical;API

SMILES

CC(=O)OC1=CC=C(C=C1)C=CC2=CC(=CC(=C2)OC(=O)C)OC(=O)C

Synonyms

1,3-Benzenediol, 5-[(E)-2-[4-(acetyloxy)phenyl]ethenyl]-, diacetate/3-Acetoxy-5-[(E)-2-(4-acetoxyphenyl)vinyl]phenyl acetate/5-[(1E)-2-[4-(acetyloxy)phenyl]ethenyl]-1,3-Benzenediol-1,3-diacetate/Acetyl trans-resveratrol/(E)-5-(4-Acetoxystyryl)-1,3-phenylene diacetate/Triacetyl resveratrol/3,4',5-Triacetoxy-trans-stilbene/Acetyl-trans-resveratrol/Acetic acid 4-[2-(3,5-diacetoxyphenyl)vinyl]phenyl ester/resveratrol triacetate/Acetyl-resveratrol

IUPAC Name

[4-[(E)-2-(3,5-diacetyloxyphenyl)ethenyl]phenyl] acetate

Applications

Density

1.2±0.1 g/cm3

Solubility

Methanol; Chloroform

Flash Point

221.4±30.2 °C

Boiling Point

504.8±50.0 °C at 760 mmHg

Melting Point

117.0 to 121.0 °C

InChl

InChl Key

WGK Germany

RID/ADR

HS Code Reference

Personal Projective Equipment

Correct Usage

For Reference Standard and R&D, Not for Human Use Directly.

Meta Tag

provides coniferyl ferulate(CAS#:42206-94-0) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of coniferyl ferulate are included as well.>> amp version: coniferyl ferulate

No Technical Documents Available For This Product.

PMID

30543707

Abstract

Introduction
Golden retrievers are over-represented in cases of taurine-deficient dilated cardiomyopathy and recently a surge in cases has prompted further investigation.

Objective
To describe the clinical, dietary, and echocardiographic features in golden retrievers diagnosed with taurine deficiency and dilated cardiomyopathy, and to determine specific dietary associations. A second aim was to determine the whole blood taurine concentrations in a representative sample of healthy golden retrievers.

Animals
Twenty-four client-owned golden retrievers with documented taurine deficiency and dilated cardiomyopathy and 52 healthy client-owned golden retrievers.

Methods
In this multicenter prospective observational study, baseline and follow-up echocardiographic data, complete diet and medical histories, and whole blood, plasma, or serum taurine concentrations were obtained. Baseline and follow-up echocardiographic data were compared. Associations were evaluated between specific diets and taurine deficiency or congestive heart failure. The prevalence of low whole blood taurine concentrations in the healthy golden retrievers was calculated.

Results
Twenty-three of 24 dogs diagnosed with taurine deficiency and dilated cardiomyopathy were fed diets that were either grain-free, legume-rich, or a combination of these factors. None of these diets were feeding trial tested using Association of American Feed Control Officials (AAFCO) procedures. Twenty-three of 24 dogs had significant improvement in their echocardiographic parameters and normalization of taurine concentrations following diet change and taurine supplementation. Nine of 11 dogs diagnosed with congestive heart failure (CHF) had resolution of their congestion at follow-up with five no longer requiring diuretic therapy and four tolerating diuretic dose reduction by >50%.

Conclusions
Certain diets and diet characteristics were associated with the development of taurine deficiency. Taurine deficiency and dilated cardiomyopathy in golden retrievers is likely multifactorial, including a combination of dietary, metabolic, and genetic factors.

Title

Taurine deficiency and dilated cardiomyopathy in golden retrievers fed commercial diets

Author

Joanna L. Kaplan, Data curation, Formal analysis, Investigation, Methodology, Resources, Software, Visualization, Writing - original draft, Writing - review & editing,1 Joshua A. Stern, Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Project administration, Resources, Software, Supervision, Validation, Visualization, Writing - original draft, Writing - review & editing,1,* Andrea J. Fascetti, Methodology, Resources, Visualization, Writing - review & editing,#2 Jennifer A. Larsen, Methodology, Resources, Visualization, Writing - review & editing,#2 Hannah Skolnik, Conceptualization, Data curation, Investigation, Methodology,1 Gordon D. Peddle, Resources, Writing - review & editing,3 Richard D. Kienle, Resources, Writing - review & editing,4 Andrew Waxman, Resources, Writing - review & editing,5 Michael Cocchiaro, Resources, Writing - review & editing,6 Catherine T. Gunther-Harrington, Resources, Writing - review & editing,1 Tyler Klose, Resources,7 Kendra LaFauci, Resources, Writing - review & editing,8 Bonnie Lefbom, Resources,9 Maggie Machen Lamy, Resources,10 Rebecca Malakoff, Resources, Writing - review & editing,11 Satoko Nishimura, Resources, Writing - review & editing,1 Maureen Oldach, Resources, Writing - review & editing,1 Steven Rosenthal, Resources,12 Christopher Stauthammer, Resources, Writing - review & editing,13 Lynne O’Sullivan, Resources, Writing - review & editing,14 Lance C. Visser, Resources, Writing - review & editing,1 Regan William, Resources, Writing - review & editing,15 and Eric Ontiveros, Data curation, Investigation, Methodology, Resources, Visualization, Writing - review & editing1

Publish date

2018 Dec 13

PMID

25741897

Abstract

In further study of our series of six-membered ring-containing nucleic acids, different 1′,3′-di-O-methyl altropyranoside nucleoside analogs (DMANA) were synthesized comprising all four base moieties, adenine, cytosine, uracil and guanine. Following assembly into oligonucleotides (ONs), their affinity for natural oligonucleotides was evaluated by thermal denaturation of the respective duplexes. Data were compared with results obtained previously for both anhydrohexitol (HNAs) and 3′-O-methylated altrohexitol modified ONs (MANAs). We hereby demonstrate that ONs modified with DMANA monomers, unlike some of our previously described analogues with constrained 6-membered hexitol rings, did not improve thermodynamic stability of dsRNA complexes, most probably in view of an energetic penalty when forced in the required 1C4 pairing conformation. Overall, a single incorporation was more or less tolerated or even positive for the adenine congener, but incorporation of a second modification afforded a slight destabilization (except for A), while a fully modified sequence displayed a thermal stability of ?0.3 °C per modification. The selectivity of pairing remained very high, and the new modification upon incorporation into a DNA strand, strongly destabilized the corresponding DNA duplexes. Unfortunately, this new modification does not bring any advantage to be further evaluated for antisense or siRNA applications.

KEYWORDS

modified oligonucleotides, hexitol nucleic acids, pairing behaviour, hybridisation, constrained oligonucleotides

Title

Hybridisation Potential of 1',3'-Di-O-methylaltropyranoside Nucleic Acids

Author

Akkaladevi Venkatesham,† Dhuldeo Kachare,† Guy Schepers, Jef Rozenski, Mathy Froeyen, and Arthur Van Aerschot*

Publish date

2015 Mar 3.

PMID

31391954

Abstract

In the title 1:2 co-crystal, C10H9N2 +·(C6H7.75O6·C6H7.25O6)?, l-ascorbic acid (LAA) and 4,4′-bi­pyridine (BPy) co-crystallize in the chiral space group P21 with two mol­ecules of LAA, and one mol­ecule of bpy in the asymmetric unit. The structure was modeled in two parts due to possible proton transfer from LAA to the corresponding side of the bpy mol­ecule having an occupancy of approximately 0.25 and part 2 with an occupancy of approximately 0.75. In this structure, LAA forms hydrogen bonds with neighboring LAA mol­ecules, forming extended sheets of LAA mol­ecules which are bridged by bpy mol­ecules. A comparison to a related and previously published co-crystal of LAA and 3-bromo-4-pyridone is presented.

KEYWORDS

crystal structure, co-crystal, charge transfer, l-ascorbic acid, 4,4′-bi­pyridine

Title

Partial charge transfer in the salt co-crystal of l-ascorbic acid and 4,4′-bi­pyridine

Author

Eric Sylvester,a Mitchell McGovern,a An Young Lee,a Phanxico Nguyen,a Jungeun Park,a and Jason B. Benedictb,*

Publish date

2019 May 3.