Catalogue Number
AV-B02346
Analysis Method
HPLC,NMR,MS
Specification
95%
Storage
2-8°C
Molecular Weight
840.95
Appearance
Powder
Botanical Source
Structure Type
Steroids
Category
Standards;Natural Pytochemical;API
SMILES
CC1C(C(CC(O1)OC2CCC3(C(C2)CCC45C3CCC6(C4(O5)CCC6C7=CC(=O)OC7)C)C)OC)OC8C(C(C(C(O8)COC9C(C(C(C(O9)CO)O)O)O)O)O)O
Synonyms
Card-20(22)-enolide, 8,14-epoxy-3-[[O-β-D-glucopyranosyl-(1->6)-O-β-D-glucopyranosyl-(1->4)-2,6-dideoxy-3-O-methyl-β-D-lyxo-hexopyranosyl]oxy]-, (3β,5β)-/(3β,5β)-3-{[β-D-Glucopyranosyl-(1->6)-β-D-glucopyranosyl-(1->4)-2,6-dideoxy-3-O-methyl-β-D-lyxo-hexopyranosyl]oxy}-8,14-epoxycard-20(22)-enolide
IUPAC Name
3-[(1S,3R,6R,7R,10R,11S,14S,16R)-14-[(2R,4R,5S,6R)-4-methoxy-6-methyl-5-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-[[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxymethyl]oxan-2-yl]oxyoxan-2-yl]oxy-7,11-dimethyl-2-oxapentacyclo[8.8.0.01,3.03,7.011,16]octadecan-6-yl]-2H-furan-5-one
Density
1.5±0.1 g/cm3
Solubility
Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Flash Point
Boiling Point
Melting Point
InChl
InChl Key
FHDXJOXIIORNFS-HRQGBTQPSA-N
WGK Germany
RID/ADR
HS Code Reference
Personal Projective Equipment
Correct Usage
For Reference Standard and R&D, Not for Human Use Directly.
Meta Tag
provides coniferyl ferulate(CAS#:88721-09-9) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of coniferyl ferulate are included as well.>> amp version: coniferyl ferulate
No Technical Documents Available For This Product.
17681508
Objective
This study examined whether inflammation adds to the prediction of coronary heart disease (CHD) beyond Metabolic Syndrome (MetS), and whether these associations differ between sexes.
Methods and Results
Among 30,111 women from the Nurses’ Health Study and 16,695 men from the Health Professionals Follow-up Study without prior cardiovascular disease, 249 women and 266 men developed nonfatal myocardial infarction or fatal CHD during 8 and 6 years of follow-up, respectively. Controls were selected 2:1 within each cohort matched on age, smoking, and date of blood draw. Subjects with MetS had a significantly increased relative risk (RR) of CHD compared to individuals without MetS, and this RR was significantly higher in women (3.01; 95%-CI 1.98-4.57) than in men (1.62; 95%-CI 1.13-2.33; p interaction = 0.03). Adjustment for most inflammatory markers did not substantially attenuate the risk estimates, although the association was no longer significant in men after adjustment for CRP. Vice versa, associations of inflammatory markers with CHD risk among women were no longer significant after further adjustment for MetS. Among men, CRP and sICAM remained significant predictors of CHD independent of MetS.
Conclusions
MetS is a stronger predictor of CHD in women than in men. Most inflammatory markers did not add appreciable information beyond MetS to predict CHD; only CRP and sICAM remained independently predictive of CHD among men. The basis for these sex-based differences warrants further study.
Metabolic syndrome, inflammation, epidemiology, cohort studies, coronary heart disease, risk factors
Inflammation, the Metabolic Syndrome, and Risk of Coronary Heart Disease in Women and Men
Tobias Pischon, MD, MPH,* Frank B. Hu, MD, PhD,†‡|| Kathryn M. Rexrode, MD, MPH,§ Cynthia J. Girman, DrPH,# JoAnn E. Manson, MD, DrPH,†§ and Eric B Rimm, ScD†‡||
2009 Mar 1
24914546
Background
Persons with certain neurological conditions have higher mortality rates than the population without neurological conditions, but the risk factors for increased mortality within diagnostic groups are less well understood. The interRAI CHESS scale has been shown to be a strong predictor of mortality in the overall population of persons receiving health care in community and institutional settings. This study examines the performance of CHESS as a predictor of mortality among persons with 11 different neurological conditions.
Methods
Survival analyses were done with interRAI assessments linked to mortality data among persons in home care (n?=?359,940), complex continuing care hospitals/units (n?=?88,721), and nursing homes (n?=?185,309) in seven Canadian provinces/territories.
Results
CHESS was a significant predictor of mortality in all 3 care settings for the 11 neurological diagnostic groups considered after adjusting for age and sex. The distribution of CHESS scores varied between diagnostic groups and within diagnostic groups in different care settings.
Conclusions
CHESS is a valid predictor of mortality in neurological populations in community and institutional care. It may prove useful for several clinical, administrative, policy-development, evaluation and research purposes. Because it is routinely gathered as part of normal clinical practice in jurisdictions (like Canada) that have implemented interRAI assessment instruments, CHESS can be derived without additional need for data collection.
Use of the interRAI CHESS Scale to Predict Mortality among Persons with Neurological Conditions in Three Care Settings
John P. Hirdes, 1 , * Jeffrey W. Poss, 1 Lori Mitchell, 2 Lawrence Korngut, 3 and George Heckman 1
2014
28469920
Background
Humpback whales are known to undertake long-distance migration between feeding and breeding sites, but their movement behavior within their breeding range is still poorly known. Satellite telemetry was used to investigate movement of humpback whales during the breeding season and provide further understanding of the breeding ecology and sub-population connectivity within the southwest Indian Ocean (SWIO). Implantable Argos satellite tags were deployed on 15 whales (7 males and 6 females) during the peak of the breeding season in Reunion Island. A switching-state-space model was applied to the telemetry data, in order to discriminate between “transiting” and “localized” movements, the latter of which relates to meandering behavior within putative breeding habitats, and a kernel density analysis was used to assess the spatial scale of the main putative breeding sites.
Results
Whales were tracked for up to 71 days from 31/07/2013 to 16/10/2013. The mean transmission duration was 25.7 days and the mean distance travelled was 2125.8 km. The tracks showed consistent movement of whales from Reunion to Madagascar, demonstrating a high level of connectivity between the two sub-regions, and the use of yet unknown breeding sites such as underwater seamounts (La Perouse) and banks (Mascarene Plateau). A localized movement pattern occurred in distinct bouts along the tracks, suggesting that whales were involved in breeding activity for 4.3 consecutive days on average, after which they resume transiting for an average of 6.6 days. Males visited several breeding sites within the SWIO, suggesting for the first time a movement strategy at a basin scale to maximize mating. Unexpectedly, females with calf also showed extensive transiting movement, while they engaged in localized behavior mainly off Reunion and Sainte-Marie (East Madagascar).
Conclusions
The results indicated that whales from Reunion do not represent a discrete population. Discrete breeding sites were identified, thereby highlighting priority areas for conservation. The study is a first attempt to quantify movement of humpback whales within the southwestern Indian Ocean breeding range. We demonstrate a wandering behavior with stopovers at areas that likely represent key breeding habitat, a strategy which may enhance likelihood of individual reproductive success.
Electronic supplementary material
The online version of this article (doi:10.1186/s40462-017-0101-5) contains supplementary material, which is available to authorized users.
Humpback whales, Satellite tracking, Reunion, Indian Ocean, Breeding behavior, Movement pattern
Continuous movement behavior of humpback whales during the breeding season in the southwest Indian Ocean: on the road again!
Violaine Dulau,corresponding author1 Patrick Pinet,2 Ygor Geyer,3 Jacques Fayan,4 Philippe Mongin,4 Guillaume Cottarel,1 Alexandre Zerbini,3,5,6 and Salvatore Cerchio7,8,9
2017;
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