This product is isolated and purified from the herbs of Lycopodium serratum Thunb.
(2S,4aR,5S,8aR,2'S,4a'R,5'S,8a'R)-5,5'-(1,2-Ethanediyl)bis(1,1,4a-trimethyl-6-methylenedecahydro-2-naphthalenol)/1-Hydroxymethylmidazolam/1'-Hydroxymidazolam/1-OH-midazolam/1'-hydroxy-MDZ/2-Naphthalenol, 5,5'-(1,2-ethanediyl)bis[decahydro-1,1,4a-trimethyl-6-methylene-, (2S,4aR,5S,8aR,2'S,4'aR,5'S,8'aR)-
Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
524.3±50.0 °C at 760 mmHg
HS Code Reference
Personal Projective Equipment
For Reference Standard and R&D, Not for Human Use Directly.
provides coniferyl ferulate(CAS#:511-01-3) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of coniferyl ferulate are included as well.>> amp version: coniferyl ferulate
In order to find new acetylcholinesterase inhibitors from natural sources which have therapeutic potential in the treatment of Alzheimer’s disease, the chloroform : methanol (1 : 1) extracts of five Lycopodium species ( L. clavatum L., L. selago L., L. annotinum L., L. alpinum L., and L. complanatum ssp. chamaecyparissus A. (Br.) Doll.), growing in Turkey (Lycopodiaceae), were screened in vitro by the Ellman spectrophotometric method at 1 mg/ml concentration. Among these extracts, only the extract of L. clavatum was found to be active (49.85 %). Bioassay-guided fractionation of the chloroform extract of L. clavatum led to the isolation of alpha-onocerin (IC 50 = 5.2 microM), a well-known triterpenoid, as the responsible compound for the activity.
Alpha-onocerin: an acetylcholinesterase inhibitor from Lycopodium clavatum.
Orhan I1, Terzioglu S, Sener B
A detailed NMR and MS analysis of alpha-onocerin was performed in order to provide precise phytochemical reference for structure identification and quality control of this analytical lead compound from Ononis spinosa the roots of which are widely used as a diuretic drug. Unambiguous 1H- and 13C-NMR assignments revealed that the linkage of two subunits were confirmed to possess identical stereochemistries in this triterpenoid.
Comprehensive spectroscopic investigation of alpha-onocerin