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Antirhine

$855

  • Brand : BIOFRON

  • Catalogue Number : AV-B02859

  • Specification : 97%

  • CAS number : 16049-28-8

  • Formula : C19H24N2O

  • Molecular Weight : 296.41

  • PUBCHEM ID : 5462421

  • Volume : 5mg

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Catalogue Number

AV-B02859

Analysis Method

HPLC,NMR,MS

Specification

97%

Storage

2-8°C

Molecular Weight

296.41

Appearance

Powder

Botanical Source

Structure Type

Alkaloids

Category

Standards;Natural Pytochemical;API

SMILES

C=CC(CO)C1CCN2CCC3=C(C2C1)NC4=CC=CC=C34

Synonyms

Indolo[2,3-a]quinolizine-2-ethanol, β-ethenyl-1,2,3,4,6,7,12,12b-octahydro-, (βR,2S,12bS)-/(2R)-2-[(2S,12bS)-1,2,3,4,6,7,12,12b-Octahydroindolo[2,3-a]quinolizin-2-yl]-3-buten-1-ol

IUPAC Name

(2R)-2-[(2S,12bS)-1,2,3,4,6,7,12,12b-octahydroindolo[2,3-a]quinolizin-2-yl]but-3-en-1-ol

Applications

Density

1.2±0.1 g/cm3

Solubility

Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.

Flash Point

249.1±27.3 °C

Boiling Point

488.2±40.0 °C at 760 mmHg

Melting Point

InChl

InChl Key

RYMNVEAAYOFGCI-DEYYWGMASA-N

WGK Germany

RID/ADR

HS Code Reference

Personal Projective Equipment

Correct Usage

For Reference Standard and R&D, Not for Human Use Directly.

Meta Tag

provides coniferyl ferulate(CAS#:16049-28-8) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of coniferyl ferulate are included as well.>> amp version: coniferyl ferulate

No Technical Documents Available For This Product.

PMID

22104610

Abstract

Background
Information comparing subjective and objective measurements of adherence to study medications and the effects of adherence on treatment-related differences in asthma clinical trials are limited.

Objective
We sought to compare subjective and objective measurements of children’s adherence to inhaled corticosteroids or placebo and to determine whether adherence to study medications modified treatment-related differences in outcomes.

Methods
In an ancillary study conducted in 3 of 8 Childhood Asthma Management Program Clinical Centers, adherence was assessed by using self-reported and objective data in 5- to 12-year-old children with mild or moderate asthma who were randomly assigned to 200 μg of inhaled budesonide twice per day (n = 84) or placebo (n = 56) for 4 years. The κ statistic was used to evaluate agreement between self-reported adherence (daily diary cards) and objectively measured adherence (number of doses left in study inhalers). Multivariable analyses were used to determine whether adherence to study treatment modified treatment-related differences in outcomes.

Results
Adherence of less than 80% was seen in 75% of 140 children when adherence was measured objectively but only in 6% of children when measured by means of self-report. There was poor agreement between objective and subjective measurements of adherence of at least 80% (κ = 0.00; 95% CI, ?0.05 to 0.04); self-reported adherence over the 4-year period generally overestimated objectively measured adherence (93.6% vs 60.8%, P < .0001). There was little evidence to indicate that adherence modified treatment-related differences in outcomes. Conclusion Researchers should use objective rather than self-reported adherence data to identify clinical trial participants with low levels of adherence to study treatment.

KEYWORDS

Asthma, adherence, compliance, children, lung growth, inhaled corticosteroids, budesonide, clinical trial

Title

Adherence to inhaled corticosteroids: An ancillary study of the Childhood Asthma Management Program clinical trial

Author

Jerry A. Krishnan, MD, PhD,a Bruce G. Bender, PhD,b Frederick S. Wamboldt, MD,b Stanley J. Szefler, MD,b N. Franklin Adkinson, Jr, MD,c Robert S. Zeiger, MD, PhD,d Robert A. Wise, MD,c Andrew L. Bilderback, MS,c and Cynthia S. Rand, PhDc, on behalf of the Adherence Ancillary Study Group*

Publish date

2013 Jan 1.

PMID

20226308

Abstract

Despite the potential role of chitinases and chitinase-like proteins in the pathogenesis of asthma, variants in their respective genes are not associated with asthma, changes in lung physiology or allergy-related phenotypes in Caucasian children.

KEYWORDS

chitinase, chitinase-like protein, CHIA, CHIT1, CHI13L1, YKL-40, AMCase, SNPs, asthma

Title

Polymorphisms of Chitinases are not Associated with Asthma

Author

Ann Chen Wu, MD, MPH,1,2,3 Jessica Lasky-Su, PhD,4 Christine A. Rogers, PhD,5 Barbara J. Klanderman, PhD,3 and Augusto Litonjua, MD, MPH3,4,6

Publish date

2011 Mar 1.

PMID

26527330

Abstract

We experimentally perform the simulation of open quantum dynamics in single-qudit systems. Using a spatial light modulator as a dissipative optical device, we implement dissipative-dynamical maps onto qudits encoded in the transverse momentum of spontaneous parametric down-converted photon pairs. We show a well-controlled technique to prepare entangled qudits states as well as to implement dissipative local measurements; the latter realize two specific dynamics: dephasing and amplitude damping. Our work represents a new analogy-dynamical experiment for simulating an open quantum system.

Title

Experimental simulation of decoherence in photonics qudits

Author

B. Marques,a,1,2 A. A. Matoso,1 W. M. Pimenta,1 A. J. Gutierrez-Esparza,1 M. F. Santos,1 and S. Padua1

Publish date

2015