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Arecoline hydrobromide

$43

  • Brand : BIOFRON

  • Catalogue Number : BF-A3025

  • Specification : 98%

  • CAS number : 300-08-3

  • Formula : C8H14BrNO2

  • Molecular Weight : 236.11

  • PUBCHEM ID : 9301

  • Volume : 100mg

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Catalogue Number

BF-A3025

Analysis Method

HPLC,NMR,MS

Specification

98%

Storage

-20℃

Molecular Weight

236.11

Appearance

White crystalline powder

Botanical Source

fruits of Areca catechu

Structure Type

Alkaloids

Category

Standards;Natural Pytochemical;API

SMILES

CN1CCC=C(C1)C(=O)OC.Br

Synonyms

1-Methyl-1,2,5,6-tetrahydro-pyridin-3-carbonsaeure-methylester,Hydrobromid/Methyl 1-methyl-1,2,5,6-tetrahydropyridine-3-carboxylate hydrobromide (1:1)/Arecaidine methyl ester hydrobromide/methyl 1-methyl-1,2,5,6-tetrahydropyridine-3-carboxylate hydrobromide/3-Pyridinecarboxylic acid, 1,2,5,6-tetrahydro-1-methyl-, methyl ester, hydrobromide (1:1)/Arecoline/Methyl 1-methyl-1,2,5,6-tetrahydro-3-pyridinecarboxylate hydrobromide/ARECOLINE HBr/Methyl 1,2,5,6-Tetrahydro-1-methylnicotinate Hydrobromide/Methyl-1-methyl-1,2,5,6-tetrahydro-3-pyridincarboxylathydrobromid/1-methyl-1,2,5,6-tetrahydro-pyridine-3-carboxylic acid methyl ester,hydrobromide/arecolinium bromide/Methyl 1-methyl-1,2,5,6-tetrahydro-3-pyridinecarboxylate hydrobromide (1:1)/Arecoline hydrobromide/Taeniolin/Arecoline bromide/1,2,5,6-Tetrahydro-1-methyl-3-pyridinecarboxylic Acid Methyl Ester Hydrobromide/3-Pyridinecarboxylic acid, 1,2,5,6-tetrahydro-1-methyl-, methyl ester, hydrobromide (9CI)/1-Methyl-1,2,5,6-tetrahydro-3-pyridinecarboxylate de methyle bromhydrate/Arecoline (hydrobromide)

IUPAC Name

methyl 1-methyl-3,6-dihydro-2H-pyridine-5-carboxylate;hydrobromide

Density

Solubility

Methanol

Flash Point

81.1ºC

Boiling Point

209ºC at 760mmHg

Melting Point

171-175 °C

InChl

InChl Key

WGK Germany

RID/ADR

HS Code Reference

2933990000

Personal Projective Equipment

Correct Usage

For Reference Standard and R&D, Not for Human Use Directly.

Meta Tag

provides coniferyl ferulate(CAS#:300-08-3) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of coniferyl ferulate are included as well.>> amp version: coniferyl ferulate

No Article Available.


Description :

Arecoline Hydrobromide is a muscarinic acetylcholine receptor agonist. Target: mAChRArecoline is an alkaloid found in the areca nut. Arecoline. a drug obtained from the Areca Catechu L., induced a dose-dependent antinociception (0.3-1 mg kg(-1) i.p.) which was prevented by the muscarinic antagonists pirenzepine (0.1 microg per mouse i.c.v.) and S-(-)-ET-126 (0.01 microg per mouse i.c.v.) [1]. Arecoline exerts its excitatory actions by binding to M2-muscarinic receptors on the cell membrane of neurons of the locus coeruleus [2]. Arecoline (1 nM - 1 microM) produced a concentration-dependent contraction in both the longitudinal and the circular smooth muscle of rabbit colon. Atropine (10 microM) abolished the arecoline (80 nM)--induced contraction. M3 receptor antagonist, 4 - DAMP (0.4 microM), abolished the arecoline (80 nM)--related response, whereas M2 receptor antagonist, gallamine (0.4 microM), did not affect the effect of arecoline. These results suggest that arecoline excites the colonic motility via M3 receptor in rabbits [3].