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Constituents of the fruits of Peatasites tatewakianus were investigated. A new compound, namely bakkenolide-VI (1), was isolated. The structures was elucidated on the basis of 1D, 2D NMR, TOF-MS and ESI-MS techniques, and physicochemical properties. The neuroprotective activity of the new compound was assayed with primary cultured neurons exposed to oxygen-glucose deprivation and oxidative insults.
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A new neuroprotective bakkenolide from the rhizome of Peatasites tatewakianus.
Sun ZL1, Gao GL, Luo JY, Zhang XL, Zhang M, Feng J.