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Benzyl 2,4-dihydroxyphenyl ketone

$64

  • Brand : BIOFRON

  • Catalogue Number : BN-O1135

  • Specification : 98%(HPLC)

  • CAS number : 3669-41-8

  • Formula : C14H12O3

  • Molecular Weight : 228.24

  • PUBCHEM ID : 138005

  • Volume : 5mg

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Catalogue Number

BN-O1135

Analysis Method

Specification

98%(HPLC)

Storage

2-8°C

Molecular Weight

228.24

Appearance

Botanical Source

Structure Type

Category

SMILES

C1=CC=C(C=C1)CC(=O)C2=C(C=C(C=C2)O)O

Synonyms

2',4'-Dihydroxy-2-phenylacetophenone/1-(2,4-Dihydroxyphenyl)-2-phenylethanone/Ethanone, 1-(2,4-dihydroxyphenyl)-2-phenyl-/Benzyl 2,4-Dihydroxyphenyl Ketone

IUPAC Name

1-(2,4-dihydroxyphenyl)-2-phenylethanone

Density

1.3±0.1 g/cm3

Solubility

Flash Point

227.9±18.3 °C

Boiling Point

429.8±20.0 °C at 760 mmHg

Melting Point

112-116 °C(lit.)

InChl

InChl Key

VFQKAJVKZKHVPD-UHFFFAOYSA-N

WGK Germany

RID/ADR

HS Code Reference

Personal Projective Equipment

Correct Usage

For Reference Standard and R&D, Not for Human Use Directly.

Meta Tag

provides coniferyl ferulate(CAS#:3669-41-8) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of coniferyl ferulate are included as well.>> amp version: coniferyl ferulate

No Technical Documents Available For This Product.

PMID

8622994

Abstract

We show that interleukin 3 (IL-3) enhances the generation of tumor-specific cytotoxic T lymphocytes (CTLs) through the stimulation of host antigen-presenting cells (APCs). The BALB/c (H-2d) spontaneous lung carcinoma line 1 was modified by gene transfection to express ovalbumin as a nominal “tumor antigen” and to secrete IL-3, a cytokine enhancing myeloid development. IL-3-transfected tumor cells are less tumorigenic than the parental cell line, and tumor-infiltrating lymphocytes isolated from these tumors contain increased numbers of tumor-specific CTLs. By using B3Z86/90.14 (B3Z), a unique T-cell hybridoma system restricted to ovalbumin/H-2b and implanting the tumors in (BALB/c x C57BL/6)F1 (H-2d/b) mice, we demonstrate that the IL-3-transfected tumors contain an increased number of a rare population of host cells that can process and “re-present” tumor antigen to CTLs. Electron microscopy allowed direct visualization of these host APCs, and these studies, along with surface marker phenotyping, indicate that these APCs are macrophage-like. The identification of these cells and their enhancement by IL-3 offers a new opportunity for tumor immunotherapy.

Title

Interleukin 3 enhances cytotoxic T lymphocyte development and class I major histocompatibility complex "re-presentation" of exogenous antigen by tumor-infiltrating antigen-presenting cells.

Author

B A Pulaski, K Y Yeh, N Shastri, K M Maltby, D P Penney, E M Lord, and J G Frelinger

Publish date

1996 Apr 16;

PMID

3038847

Abstract

A 3.4-kilobase EcoRI restriction endonuclease fragment has been cloned from the facultatively photoheterotrophic bacterium Rhodobacter sphaeroides and shown to contain the structural gene (prkA) for phosphoribulokinase (PRK) activity. The PRK activity was characterized in Escherichia coli, and the product of the reaction was identified. The prkA gene was localized to a 1,565-base-pair EcoRI-PstI restriction endonuclease fragment and gave rise to a 33-kilodalton polypeptide both in vivo and in vitro. The gene product produced in E. coli was shown to be identical to the gene product produced in R. sphaeroides. The amino acid sequence for the amino-terminal region deduced from the DNA sequence confirmed that derived for partially purified PRK derived from both E. coli and R. sphaeroides. In addition, the 3.4-kilobase EcoRI restriction endonuclease fragment coded for a 37-kilodalton polypeptide of unknown function, and preliminary evidence indicates that this DNA fragment is linked to genes coding for other activities significant in photosynthetic carbon assimilation. The genetic organization and proposed operon structure of this DNA fragment are discussed.

Title

Cloning of the gene for phosphoribulokinase activity from Rhodobacter sphaeroides and its expression in Escherichia coli.

Author

P L Hallenbeck and S Kaplan

Publish date

1987 Aug;

PMID

24662081

Abstract

Continuous phytochemical studies of the crude extract of Luo Han Guo (Siraitia grosvenorii) furnished three additional new cucurbitane triterpene glycosides, namely 11-deoxymogroside V, 11-deoxyisomogroside V, and 11-deoxymogroside VI. The structures of all the isolated compounds were characterized on the basis of extensive NMR and mass spectral data as well as hydrolysis studies. The complete 1H- and 13C-NMR spectral assignments of the three unknown compounds are reported for the first time based on COSY, TOCSY, HSQC, and HMBC spectroscopic data.

KEYWORDS

Siraitia grosvenorii, curcubitaceae, Luo Han Guo, curcubitane glycosides, structure elucidation, NMR, MS

Title

Additional New Minor Cucurbitane Glycosides from Siraitia grosvenorii

Author

Indra Prakash1,* and Venkata Sai Prakash Chaturvedula2

Publish date

2014 Mar;


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