This product is isolated and purified from the herbs of Bergenia purpurascens
berberoline chloride/2,3-methylenedioxy-9-hydroxy-10-methoxyprotoberberine chloride/Berberrubine chloride/Pyrano[3,2-c]benzopyran-6(2H)-one, 3,4,8,10-tetrakis(acetyloxy)-2-[(acetyloxy)methyl]-3,4,4a,10b-tetrahydro-9-methoxy-, (2R,3R,4R,4aS,10bS)-/Beroline chloride/berberrubine hydrochloride/bergenin 3,4,8,10,11-pentaacetate/beberrubine chloride/9-Demethoxy-9-hydroxyberberinium chloride/penta-O-acetyl bergenin/Bergenin-pentaacetat/Chileninone/hydrochloride berberrubine/Berberubine hydrochloride/(2R,3R,4R,4aS,10bS)-2-(Acetoxymethyl)-9-methoxy-6-oxo-2,3,4,4a,6,10b-hexahydropyrano[3,2-c]isochromene-3,4,8,10-tetrayl tetraacetate/3,4,8,10,11-penta-O-acetylbergenin/9-Berberoline chloride
Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
582.4±50.0 °C at 760 mmHg
HS Code Reference
Personal Projective Equipment
For Reference Standard and R&D, Not for Human Use Directly.
provides coniferyl ferulate(CAS#:14531-47-6) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of coniferyl ferulate are included as well.>> amp version: coniferyl ferulate
New peptides with potential antimicrobial activity, encrypted in milk protein sequences, were searched for with the use of bioinformatic tools. The major milk proteins were hydrolyzed in silico by 28 enzymes. The obtained peptides were characterized by the following parameters: molecular weight, isoelectric point, composition and number of amino acid residues, net charge at pH 7.0, aliphatic index, instability index, Boman index, and GRAVY index, and compared with those calculated for known 416 antimicrobial peptides including 59 antimicrobial peptides (AMPs) from milk proteins listed in the BIOPEP database. A simple analysis of physico-chemical properties and the values of biological activity indicators were insufficient to select potentially antimicrobial peptides released in silico from milk proteins by proteolytic enzymes. The final selection was made based on the results of multidimensional statistical analysis such as support vector machines (SVM), random forest (RF), artificial neural networks (ANN) and discriminant analysis (DA) available in the Collection of Anti-Microbial Peptides (CAMP database). Eleven new peptides with potential antimicrobial activity were selected from all peptides released during in silico proteolysis of milk proteins.
milk proteins, in silico proteolysis, antimicrobial peptides, bioinformatics
New Milk Protein-Derived Peptides with Potential Antimicrobial Activity: An Approach Based on Bioinformatic Studies
Bartłomiej Dziuba1,* and Marta Dziuba2
Attempted RCM of 2,2′-bis(allyloxy)-1,1′-binaphthyl resulted in a Claisen-type rearrangement of a postulated labile dioxacyclodecine proceeding at room temperature and followed by [2+2] cycloaddition. Structures of products were confirmed by X-ray crystallography. A mechanistic rationalisation based on relative stabilities of proposed intermediates and transition states is provided.
DFT calculations, Grubbs II catalyst, cage compounds, spiro-compounds, chiral macrocycle
Tandem RCM-Claisen Rearrangement-[2+2] Cycloaddition of O,O'-(But-2-en-1,4-diyl)-bridged Binaphthols
Michael Abraham,1 Wolfgang Reischl,1 Karl A. Kirchner,2 Alexander Roller,3 Luis F. Veiros,4 and Michael Widhalm1,*
Environmental cues affect place cells responses, but whether this information is integrated versus segregated in distinct hippocampal cell populations is unclear. Here, we show that, in mice running on a treadmill enriched with visual-tactile landmarks, place cells are more strongly controlled by landmark-associated sensory inputs in deeper regions of CA1 pyramidal layer (CA1d). Many cells in CA1d display several firing fields correlated with landmarks, mapping positions slightly before or within the landmarks. Supporting direct involvement of sensory inputs, their firing fields show instantaneous responses to landmark manipulations, persist through change of context, and encode landmark identity and saliency. In contrast, cells located superficially in the pyramidal layer have single firing fields, are context specific and respond with slow dynamics to landmark manipulations. These findings suggest parallel and anatomically segregated circuits within CA1 pyramidal layer, with variable ties to landmarks, allowing flexible representation of spatial and non-spatial information.
Place cells are more strongly tied to landmarks in deep than in superficial CA1
Tristan Geiller,1,2 Mohammad Fattahi,1,3 June-Seek Choi,2 and Sebastien Royera,1,3