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Betaine

$52

  • Brand : BIOFRON

  • Catalogue Number : BD-D1341

  • Specification : 98%(HPLC)

  • CAS number : 107-43-7

  • Formula : C5H11NO2

  • Molecular Weight : 117.15

  • PUBCHEM ID : 247

  • Volume : 20MG

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Catalogue Number

BD-D1341

Analysis Method

HPLC,NMR,MS

Specification

98%(HPLC)

Storage

2-8℃

Molecular Weight

117.15

Appearance

White crystalline powder

Botanical Source

Beta vulgaris, Evolvulus alsinoides/Prod. by Aspergillus oryzae, Patella vulgata, Claviceps purpurea and other fungi. Occurs widely in plants such as Phoradendron rubrum and animals. Alkaloid from Abroma augusta

Structure Type

Other Alkaloids

Category

Standards;Natural Pytochemical;API

SMILES

C[N+](C)(C)CC(=O)[O-]

Synonyms

(Carboxymethyl)trimethylammonium inner salt Oxyneurine/2-N,N,N-trimethylammonio acetate/rubrinec/OXYNEURINE/(Carboxymethyl)trimethylammonium inner salt/Additive Screening/jortaine/BET/Betain/trimethylammonioacetate/Aminocoat/(Carboxymethyl)trimethylammonium inner salt,Oxyneurine/Betaine/Abromine/LYCINE/wolfberry Extract/trimethylglycine

IUPAC Name

2-(trimethylazaniumyl)acetate

Applications

Density

1.00 g/mL at 20 °C

Solubility

Methanol; Water

Flash Point

Boiling Point

Melting Point

301-305 °C (dec.)

InChl

InChl Key

WGK Germany

RID/ADR

HS Code Reference

2923900000

Personal Projective Equipment

Correct Usage

For Reference Standard and R&D, Not for Human Use Directly.

Meta Tag

provides coniferyl ferulate(CAS#:107-43-7) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of coniferyl ferulate are included as well.>> amp version: coniferyl ferulate

No Technical Documents Available For This Product.

PMID

27095614

Abstract

This study evaluated the effect of supplemental dietary betaine at three concentrations (0.0%, 0.63% and 1.26%) on semen characteristics, quality and quality after storage on boars. The trial was conducted between 22 July and 1 October 2014 in a boar stud located in Oklahoma. Boars were blocked by age within genetic line and randomly allotted to receive 0% (CON, n (line T)=22, n (line L)=10), 0.63% (BET-0.63%, n (line T)=21, n (line L)=6) or 1.26% (BET-1.26%, n (line T)=23, n (line L)=7). The diets containing betaine were fed over 10 weeks, to ensure supplemental betaine product (96% betaine) daily intakes of 16.34 and 32.68g, for the BET-0.63% and BET-1.26% diets, respectively. Serum homocysteine concentrations were less for animals with betaine treatments (P=0.016). Rectal temperatures of the boars were unaffected by betaine diets. Betaine tended to increase total sperm in the ejaculates when collectively compared with data of the control animals (P=0.093). Sperm morphology analysis indicated there was a greater percent of sperm with distal midpiece reflex (P=0.009) and tail (P=0.035) abnormalities in boars fed the BET-1.26% than boars fed the BET-0.63% diet. Betaine concentration in the seminal plasma was greater in boars with betaine treatments, with animals being fed the 0.63% and 1.26% diets having 59.2% and 54.5% greater betaine concentrations in seminal plasma as compared with boars of the control group (P=0.046). In conclusion, betaine supplementation at 0.63% and 1.26% tended to increase sperm concentration in the ejaculates by 6% and 13%, respectively, with no negative impacts on semen quality when 0.63% of betaine was included in the diet.

KEYWORDS

Betaine; Boar sperm; Homocysteine; Semen analysis.

Title

Effect of Natural Betaine on Estimates of Semen Quality in Mature AI Boars During Summer Heat Stress

Author

F A Cabezon 1 , K R Stewart 2 , A P Schinckel 1 , W Barnes 3 , R D Boyd 3 , P Wilcock 4 , J Woodliff 5

Publish date

2016 Jul 27

PMID

28664334

Abstract

Betaine is one of most studied biologically active compounds, due its role in the main biological processes. Although it may be found in several plants and roots, such as the Beta vulgaris family, present in typical diets, just a few analytical methods have been developed for its extraction from roots. A new, quick and effective procedure for the isolation and determination of betaine from two different varieties of B. vulgaris (red and gold) is presented. For betaine extraction, an accelerated solvent extraction (ASE) was coupled with solid-phase extraction. For betaine determination, a separation method based on hydrophilic interaction chromatography coupled with tandem mass spectrometry was optimized for a sensible detection of betaine by means of experimental design. Recoveries were about 93%, with RSD <5%, for both the matrices, without evidence of interfering species. The total content of betaine in extracts of various parts of plants (juice, peel, root) have been determined, obtaining concentrations in the range 3000-4000 mg/L for the juice and in the range 2-5 mg/g for the pulp and for the peel. The B. vulgaris gold species exhibited a higher concentration of betaine, compared to the red variety. Additionally, a micro extraction by packed sorbent technique and a modified quick, easy, cheap, rugged and safe (QuEChERS) procedure, were also tested and compared. Despite the lower recoveries of the latter, with respect to the ASE/SPE procedure (75-89%, RSD <1.5%), the ease of the method, which can be applied without the SPE purification procedure, can represent a positive improvement. Graphical abstract Determination of betaine from Beta vulgaris samples.

KEYWORDS

ASE; Beta vulgaris; Betaine; HILIC-MS/MS; QuEChERS; SPE.

Title

New Approaches for Extraction and Determination of Betaine From Beta Vulgaris Samples by Hydrophilic Interaction Liquid Chromatography-Tandem Mass Spectrometry

Author

Luca Rivoira 1 2 , Sylwia Studzińska 2 , Malgorzata Szultka-Młyńska 2 3 , Maria Concetta Bruzzoniti 1 , Bogusław Buszewski 4 5

Publish date

2017 Aug 5

PMID

29881379

Abstract

Betaine is known as trimethylglycine and is widely distributed in animals, plants, and microorganisms. Betaine is known to function physiologically as an important osmoprotectant and methyl group donor. Accumulating evidence has shown that betaine has anti-inflammatory functions in numerous diseases. Mechanistically, betaine ameliorates sulfur amino acid metabolism against oxidative stress, inhibits nuclear factor-κB activity and NLRP3 inflammasome activation, regulates energy metabolism, and mitigates endoplasmic reticulum stress and apoptosis. Consequently, betaine has beneficial actions in several human diseases, such as obesity, diabetes, cancer, and Alzheimer’s disease.

KEYWORDS

betaine; endoplasmic reticulum; inflammation; obesity; oxidative stress.

Title

Betaine in Inflammation: Mechanistic Aspects and Applications

Author

Guangfu Zhao 1 , Fang He 1 , Chenlu Wu 1 , Pan Li 1 , Nengzhang Li 1 , Jinping Deng 2 , Guoqiang Zhu 3 , Wenkai Ren 2 3 , Yuanyi Peng 1

Publish date

2018 May 24