We Offer Worldwide Shipping
Login Wishlist

Bilirubin

$43

  • Brand : BIOFRON

  • Catalogue Number : BF-B2007

  • Specification : 98%

  • CAS number : 635-65-4

  • Formula : C33H36N4O6

  • Molecular Weight : 584.67

  • PUBCHEM ID : 5280352

  • Volume : 20mg

In stock

Quantity
Checkout Bulk Order?

Catalogue Number

BF-B2007

Analysis Method

HPLC,NMR,MS

Specification

98%

Storage

2-8°C

Molecular Weight

584.67

Appearance

Orange crystalline powder

Botanical Source

bile of Pig

Structure Type

Alkaloids

Category

Standards;Natural Pytochemical;API

SMILES

CC1=C(NC(=C1CCC(=O)O)CC2=C(C(=C(N2)C=C3C(=C(C(=O)N3)C)C=C)C)CCC(=O)O)C=C4C(=C(C(=O)N4)C=C)C

Synonyms

(4Z,15Z)-Bilirubin IXa/21H-Biline-8,12-dipropanoic acid, 2,17-diethenyl-1,10,19,22,23,24-hexahydro-3,7,13,18-tetramethyl-1,19-dioxo-/Bilirubin: 21H-Biline-8,12-dipropanoicacid,2,17-diethenyl-1,10,19,22,23,24-hexahydro-3,7,13,18-tetramethyl-1,19-dioxo-,/Biliyubin/filirubin/Cholerythrin/(Z,Z)-Bilirubin/3-{2-({3-(2-Carboxyethyl)-4-methyl-5-[(Z)-(3-methyl-5-oxo-4-vinyl-1,5-dihydro-2H-pyrrol-2-ylidene)methyl]-1H-pyrrol-2-yl}methyl)-4-methyl-5-[(Z)-(4-methyl-5-oxo-3-vinyl-1,5-dihydro-2H-pyrrol-2-ylidene)methyl]-1H-pyrrol-3-yl}propanoic acid/1,10,19,22,23,24-hexahydro-2,7,13,17-tetramethyl-1,19-dioxo-3,18-divinyl-Biline-8,12-dipropionic acid/bilirubin/1,3,6,7-Tetramethyl-4,5-dicarboxyethyl-2,8-divinyl-(b-13)-dihydrobilenone/hemetoidin/(Z,Z)-Bilirubin IXa/Bilirubin IXa

IUPAC Name

3-[2-[[3-(2-carboxyethyl)-5-[(Z)-(3-ethenyl-4-methyl-5-oxopyrrol-2-ylidene)methyl]-4-methyl-1H-pyrrol-2-yl]methyl]-5-[(Z)-(4-ethenyl-3-methyl-5-oxopyrrol-2-ylidene)methyl]-4-methyl-1H-pyrrol-3-yl]propanoic acid

Density

1.3±0.1 g/cm3

Solubility

Methanol; DMSO

Flash Point

478.1±37.1 °C

Boiling Point

867.0±75.0 °C at 760 mmHg

Melting Point

192 °C

InChl

InChl Key

WGK Germany

RID/ADR

HS Code Reference

2933790000

Personal Projective Equipment

Correct Usage

For Reference Standard and R&D, Not for Human Use Directly.

Meta Tag

provides coniferyl ferulate(CAS#:635-65-4) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of coniferyl ferulate are included as well.>> amp version: coniferyl ferulate

PMID

31928609

KEYWORDS

Autonomic Nervous System; Bilirubin; Child; Circadian Rhythm; Hypertension

Title

Cardiometabolic Risk in Childhood: Could Bilirubin Act as a Circadian Clock-Related Mediator Via Autonomic Dysfunction?

Author

Meira E Cruz M1, Rocha I2, Bruni O3.

Publish date

2020 Jan 3

PMID

31889709

Abstract

To illuminate modern ideas about Gilbert’s syndrome (GS). GS is a common familial hyperbilirubinemia that can reduce the risk of various age-related diseases due to the antioxidant properties of bilirubin. In this case, slightly elevated unconjugated bilirubin in GS is strongly associated with a “reduced” prevalence of chronic diseases, in particular cardiovascular disease (CVD), as well as CVD-related and all-cause mortality. These reports challenge the dogma that bilirubin is simply a potentially neurotoxic byproduct of heme catabolism, and emphasize the importance of understanding its potential beneficial physiological and harmful pathophysiological effects. With this information, we hope to improve understanding of bilirubin metabolic disorders, highlight the diagnostic importance of these conditions, and map out the potential impact of GS on disease resistance.

Title

[A NEW LOOK AT GILBERT SYNDROME (LITERATURE REVIEW)].

Author

Gorbunova O1, Chernysheva E1.

Publish date

2019 Nov

PMID

31874659

Abstract

OBJECTIVE:
To study the value of serum gamma-glutamyl transpeptidase (GGT) combined with direct bilirubin (DB) in the diagnosis of biliary atresia.

METHODS:
A total of 667 infants with cholestasis who were hospitalized and treated from July 2010 to December 2018 were enrolled as subjects. According to the results of intraoperative cholangiography and follow-up, they were divided into biliary atresia group with 234 infants and cholestasis group with 433 infants. The two groups were compared in terms of age of onset, sex, and serum levels of total bilirubin (TB), DB, alanine aminotransferase (ALT), aspartate aminotransferase (AST), total bile acid (TBA), and GGT. A receiver operating characteristic (ROC) curve analysis was performed for indices with statistical significance, and the area under the ROC curve (AUC) and the optimal cut-off value for diagnosis were calculated.

RESULTS:
The biliary atresia group had a significantly younger age of onset than the cholestasis group (P<0.001). There were no significant differences in sex, ALT, and AST between the two groups (P>0.05), while the biliary atresia group had significantly higher serum levels of TB, DB, TBA, and GGT than the cholestasis group (P<0.05). GGT combined with DB had the highest AUC of 0.892 (95% confidence interval: 0.868-0.916) in the diagnosis of biliary atresia. At the optimal cut-off values of 324.0 U/L for GGT and 115.1 μmmol/L for DB, GGT combined with DB had a sensitivity of 79.8% and a specificity of 83.2% in the diagnosis of biliary atresia.

CONCLUSIONS:
GGT combined with DB has high sensitivity and specificity in the diagnosis of biliary atresia and can be used as an effective indicator for diagnosis of biliary atresia in infants.

Title

[Value of serum gamma-glutamyl transpeptidase combined with direct bilirubin in the diagnosis of biliary atresia in infants].

Author

Fu HY1, Zhao RQ, Bai GL, Yin CL, Yin RK, Li HH, Shi WN, Liu YL, Cheng LJ, Jia XY, Li GG, Zhao SG.

Publish date

2019 Dec


Description :

Bilirubin is a yellow breakdown product of heme catabolism.