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Bisoprolol fumarate

$64

  • Brand : BIOFRON

  • Catalogue Number : BN-O1030

  • Specification : 98%(HPLC)

  • CAS number : 104344-23-2

  • Formula : C22H35NO8

  • Molecular Weight : 441.52

  • PUBCHEM ID : 5281064

  • Volume : 5mg

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Catalogue Number

BN-O1030

Analysis Method

Specification

98%(HPLC)

Storage

-20℃

Molecular Weight

441.52

Appearance

Powder

Botanical Source

Structure Type

Category

SMILES

Synonyms

1-(4-{[2-(1-methylethoxy)ethoxy]methyl}phenoxy)-3-[(1-methylethyl)amino]propan-2-ol (2E)-but-2-enedioate (2:1) (salt)/Concor/Bisoprolol fumarate/Isoten/acide (2E)-but-2-enedioïque - 1-(4-{[2-(1-methylethoxy)ethoxy]methyl}phenoxy)-3-[(1-methylethyl)amino]propan-2-ol (1:2)/(2E)-But-2-endisaure--1-(4-{[2-(1-methylethoxy)ethoxy]methyl}phenoxy)-3-[(1-methylethyl)amino]propan-2-ol(1:2)/Monocor/{1-{4-[(2-isopropoxyethoxy)methyl]phenoxy}-3-(isopropylamino)propan-2-ol}2 fumarate/(+/-)-1-[4-[[2-(1-methylethoxy)ethoxy]methyl]phenoxy]-3-[(1-methyl-ethyl)amino]-2-propanol (E)-2-butenedioate/EMCOR/Euradal/SOPROL/Bisoprolol hemifumarate/1-{4-[(2-Isopropoxyethoxy)methyl]phenoxy}-3-(isopropylamino)propan-2-ol (2E)-but-2-enedioate (2:1)/(±)-Bisoprolol hemifumarate/1-(propan-2-ylamino)-3-(4-{[2-(propan-2-yloxy)ethoxy]methyl}phenoxy)propan-2-ol (2E)-but-2-enedioate (2:1)/2-Propanol, 1-[4-[[2-(1-methylethoxy)ethoxy]methyl]phenoxy]-3-[(1-methylethyl)amino]-, (2E)-2-butenedioate (2:1) (salt)/Zebeta/Detensiel/Seafuri/(+/-)-1-<4-(2-isopropoxyethoxymethyl)-phenoxy>-3-isopropylamino-2-propanol hemifumarate/1-{4-[(2-Isopropoxyethoxy)methyl]phenoxy}-3-(isopropylamino)-2-propanol (2E)-2-butenedioate (2:1)/Bisoprolol hemifumarate salt/Emconcor/Well-bi/(±)-Bisoprolol (hemifumarate)

IUPAC Name

Density

1.033 g/cm3

Solubility

Flash Point

222.9ºC

Boiling Point

445ºC at 760 mmHg

Melting Point

100ºC

InChl

InChI=1S/C15H18O3/c1-8-4-7-15-11(8)12-10(9(2)13(16)17-12)5-6-14(15,3)18-15/h4,10-12H,2,5-7H2,1,3H3/t10-,11+,12-,14-,15+/m0/s1

InChl Key

VMDFASMUILANOL-WXXKFALUSA-N

WGK Germany

RID/ADR

HS Code Reference

Personal Projective Equipment

Correct Usage

For Reference Standard and R&D, Not for Human Use Directly.

Meta Tag

provides coniferyl ferulate(CAS#:104344-23-2) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of coniferyl ferulate are included as well.>> amp version: coniferyl ferulate

No Technical Documents Available For This Product.

PMID

29602642

Abstract

Tachycardia is associated with cardiovascular mortality. Tachycardia is also a known clozapine adverse effect. However, whether clozapine-associated tachycardia is persistent is not known. Thirty clozapine-treated patients with clinical tachycardia were investigated with 24-hour ambulatory electrocardiography (ECG). Baseline peripheral heart rate (HR) was 106.7±7.8. The ambulatory ECG 24-hour-HR was 98.7±9.7. Baseline HR and 24-hour-HR correlated strongly (r=0.74, p=0.000003). Daytime HR was 106.4±9.9 and nighttime HR 89.2±12.0. Low dose bisoprolol reduced HR significantly. The high 24-hour-HR indicates a persistent tachycardia. Tachycardia should not discourage from clozapine use but the findings indicate a need of guidelines for detection and treatment of clozapine-associated tachycardia.

KEYWORDS

Cardiovascular health; Clozapine; Heart rate; Holter ECG; Schizophrenia; Tachycardia.

Title

Persistent Tachycardia in Clozapine Treated Patients: A 24-hour Ambulatory Electrocardiogram Study

Author

Bjorn M Nilsson 1, Leif Lindstrom 2, Issam Mohsen 3, Karolina Holmlov 2, Robert Boden 2

Publish date

2018 Sep;

PMID

29915527

Title

Beta Blockers in Heart Failure: More Evidence for an Old Friend

Author

Sang Hong Baek 1

Publish date

2018 Jun 18

PMID

26970547

Title

Flutamide-induced Photoleukomelanoderma

Author

Ayaka Higashiyama 1, Tomoya Yokoyama 1, Yoichi Omoto 1, Koji Habe 1, Keiichi Yamanaka 1, Hitoshi Mizutani 1

Publish date

2016 Sep;


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