We Offer Worldwide Shipping
Login Wishlist

Buddlejasaponin IVb


  • Brand : BIOFRON

  • Catalogue Number : BF-B2012

  • Specification : 98%

  • CAS number : 152580-79-5

  • Formula : C48H78O18

  • Molecular Weight : 943.12

  • PUBCHEM ID : 91758420

  • Volume : 20mg

In stock

Checkout Bulk Order?

Catalogue Number


Analysis Method






Molecular Weight




Botanical Source

Clinopodium chinense,Clinopodium urticifolium,Clinopodium polycephalum

Structure Type










1.4±0.1 g/cm3


Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.

Flash Point

591.3±34.3 °C

Boiling Point

1054.2±65.0 °C at 760 mmHg

Melting Point



InChl Key


WGK Germany


HS Code Reference


Personal Projective Equipment

Correct Usage

For Reference Standard and R&D, Not for Human Use Directly.

Meta Tag

provides coniferyl ferulate(CAS#:152580-79-5) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of coniferyl ferulate are included as well.>> amp version: coniferyl ferulate




The title compound, C35H27ClN4O3, crystallized with two independent mol­ecules (A and B) in the asymmetric unit. In both mol­ecules, the pyran and pyridine rings adopt envelope and chair conformations, respectively. The conformation of the pyrrolidine and cyclo­pentene rings differ in the two mol­ecules; twisted and flat, respectively, in mol­ecule A, but envelope and twisted, respectively, in mol­ecule B. In both mol­ecules, there is a C—H⋯N intra­molecular hydrogen bond present. In both mol­ecules, the oxygen atoms of the nitro groups are disordered as is the chlorine atom in mol­ecule B. In the crystal, the B mol­ecules are linked by C—H⋯O hydrogen bonds, forming -B-B-B- chains along [010], and by C—H⋯π inter­actions. The A and B mol­ecules are also linked by a number of C—H⋯π inter­actions, resulting in the formation a supra­molecular three-dimensional structure. In mol­ecule A, the nitro group oxygen atoms are disordered over two positions with refined occupancy ratios of the nitro group oxygen atoms O3A and O4A in 0.59 (2):0.41 (2) while in molecule B one of the nitro O atoms is disordered over two positions with a refined occupancy ratio of 0.686 (13):0.314 (13) and the chlorine atoms is disordered over two positions with a refined occupancy ratio of 0.72 (3):0.28 (3).


crystal structure, spiro compounds, cyclo­addition, piperidine, pyran, pyrrolidine, cyclo­pentene, hydrogen bonding, C—H⋯π inter­actions


Crystal structure of 6-(4-chloro­phen­yl)-6a-nitro-6a,6b,8,9,10,12a-hexa­hydro-6H,7H-spiro[chromeno[3,4-a]indolizine-12,11′-indeno­[1,2-b]quinoxaline]


S. Syed Abuthahir,a M. NizamMohideen,a,* V. Viswanathan,b D. Velmurugan,c and J. Nagasivaraod

Publish date

2019 Feb 1;




Sponge-derived actinomycetes represent a significant component of marine actinomycetes. Members of the genus Kocuria are distributed in various habitats such as soil, rhizosphere, clinical specimens, marine sediments, and sponges, however, to date, little is known about the mechanism of their environmental adaptation. Kocuria flava S43 was isolated from a coastal sponge. Phylogenetic analysis revealed that it was closely related to the terrestrial airborne K. flava HO-9041. In this study, to gain insights into the marine adaptation in K. flava S43 we sequenced the draft genome for K. flava S43 by third generation sequencing (TGS) and compared it with those of K. flava HO-9041 and some other Kocuria relatives. Comparative genomics and phylogenetic analyses revealed that K. flava S43 might adapt to the marine environment mainly by increasing the number of the genes linked to potassium homeostasis, resistance to heavy metals and phosphate metabolism, and acquiring the genes associated with electron transport and the genes encoding ATP-binding cassette (ABC) transporter, aquaporin, and thiol/disulfide interchange protein. Notably, gene acquisition was probably a primary mechanism of environmental adaptation in K. flava S43. Furthermore, this study also indicated that the Kocuria isolates from various marine and hyperosmotic environments possessed common genetic basis for environmental adaptation.


marine sponge, Kocuria flava, environmental adaptation, comparative genomics, third generation sequencing (TGS)


Comparative Genomics Provides Insights Into the Marine Adaptation in Sponge-Derived Kocuria flava S43


Wei Sun,1 Changrong Liu,1 Fengli Zhang,1 Mingzhu Zhao,2 and Zhiyong Li1,*

Publish date





Schistosomiasis is one of the most prevalent parasitic diseases worldwide and is a public health problem. Schistosoma mansoni is the most widespread species responsible for schistosomiasis in the Americas, Middle East and Africa. Adult female worms (mated to males) release eggs in the hepatic portal vasculature and are the principal cause of morbidity. Comparative separate transcriptomes of female and male adult worms were previously assessed with using microarrays and Serial Analysis of Gene Expression (SAGE), thus limiting the possibility of finding novel genes. Moreover, the egg transcriptome was analyzed only once with limited bacterially cloned cDNA libraries.

Methodology/Principal findings
To compare the gene expression of S. mansoni eggs, females, and males, we performed RNA-Seq on these three parasite forms using 454/Roche technology and reconstructed the transcriptome using Trinity de novo assembly. The resulting contigs were mapped to the genome and were cross-referenced with predicted Smp genes and H3K4me3 ChIP-Seq public data. For the first time, we obtained separate, unbiased gene expression profiles for S. mansoni eggs and female and male adult worms, identifying enriched biological processes and specific enriched functions for each of the three parasite forms. Transcripts with no match to predicted genes were analyzed for their protein-coding potential and the presence of an encoded conserved protein domain. A set of 232 novel protein-coding genes with putative functions related to reproduction, metabolism, and cell biogenesis was detected, which contributes to the understanding of parasite biology.

Large-scale RNA-Seq analysis using de novo assembly associated with genome-wide information for histone marks in the vicinity of gene models constitutes a new approach to transcriptome analysis that has not yet been explored in schistosomes. Importantly, all data have been consolidated into a UCSC Genome Browser search- and download-tool (http://schistosoma.usp.br/). This database provides new ways to explore the schistosome genome and transcriptome and will facilitate molecular research on this important parasite.


Schistosoma mansoni Egg, Adult Male and Female Comparative Gene Expression Analysis and Identification of Novel Genes by RNA-Seq


Leticia Anderson, 1 Murilo S. Amaral, 1 , 2 Felipe Beckedorff, 1 Lucas F. Silva, 1 Bianca Dazzani, 1 Katia C. Oliveira, 3 , ¤ Giulliana T. Almeida, 1 Monete R. Gomes, 1 David S. Pires, 1 , 2 João C. Setubal, 1 , 4 Ricardo DeMarco, 5 and Sergio Verjovski-Almeida 1 , 2 ,*

Publish date

2015 Dec

Description :

Empty ...