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Catalponol

$1,400 $1,260

  • Brand : BIOFRON

  • Catalogue Number : BN-O1701

  • Specification : 98%(HPLC)

  • CAS number : 34168-56-4

  • Formula : C15H18O2

  • Molecular Weight : 230.3

  • PUBCHEM ID : 169570

  • Volume : 5MG

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Catalogue Number

BN-O1701

Analysis Method

HPLC,NMR,MS

Specification

98%(HPLC)

Storage

-20℃

Molecular Weight

230.3

Appearance

Powder

Botanical Source

This product is isolated and purified from the roots of Ekmanianthe longiflora.

Structure Type

Sesquiterpenoids

Category

Standards;Natural Pytochemical;API

SMILES

CC(=CCC1CC(C2=CC=CC=C2C1=O)O)C

Synonyms

1(2H)-Naphthalenone, 3,4-dihydro-4-hydroxy-2-(3-methyl-2-buten-1-yl)-, (2R,4S)-/(2R,4S)-4-Hydroxy-2-(3-methyl-2-buten-1-yl)-3,4-dihydro-1(2H)-naphthalenone

IUPAC Name

(2R,4S)-4-hydroxy-2-(3-methylbut-2-enyl)-3,4-dihydro-2H-naphthalen-1-one

Applications

Density

1.1±0.1 g/cm3

Solubility

Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.

Flash Point

157.8±17.4 °C

Boiling Point

369.8±31.0 °C at 760 mmHg

Melting Point

InChl

InChI=1S/C15H18O2/c1-10(2)7-8-11-9-14(16)12-5-3-4-6-13(12)15(11)17/h3-7,11,14,16H,8-9H2,1-2H3/t11-,14+/m1/s1

InChl Key

BTQXIESSQVRLCV-RISCZKNCSA-N

WGK Germany

RID/ADR

HS Code Reference

2914400000

Personal Projective Equipment

Correct Usage

For Reference Standard and R&D, Not for Human Use Directly.

Meta Tag

provides coniferyl ferulate(CAS#:34168-56-4) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of coniferyl ferulate are included as well.>> amp version: coniferyl ferulate

No Technical Documents Available For This Product.

PMID

20183248

Abstract

The effects of catalponol (1) on dopamine biosynthesis and L-DOPA-induced cytotoxicity in PC12 cells were investigated. Catalponol at concentration ranges of 1-5 microM increased the intracellular levels of dopamine at 12-48 h. Catalponol at concentrations of up to 10 microM did not alter cell viability. Tyrosine hydroxylase (TH) activity was enhanced by 1 at 3 microM in a time-dependent manner, but aromatic L-amino acid decarboxylase activity was not. Catalponol also increased the intracellular levels of cyclic AMP and TH phosphorylation. In addition, catalponol at 3 microM associated with L-DOPA (20-50 microM) further enhanced the increases in dopamine levels induced by L-DOPA (50-100 microM) at 24 h. Catalponol at 2-5 microM inhibited L-DOPA (100-200 microM)-induced cytotoxicity at 48 h. These results suggest that 1 enhanced dopamine biosynthesis by inducing TH activity and protected against L-DOPA-induced cytotoxicity in PC12 cells, which was mediated by the increased levels of cyclic AMP.

Title

Catalponol enhances dopamine biosynthesis and protects against L-DOPA-induced cytotoxicity in PC12 cells.

Author

Huang HS1, Han XH, Hwang BY, Park JI, Yoo SK, Choi HS, Lim SC, Lee MK.

Publish date

2009 Oct