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Caudatin

$480

  • Brand : BIOFRON

  • Catalogue Number : BD-D0594

  • Specification : HPLC≥98%

  • CAS number : 38395-02-7

  • Formula : C28H42O7

  • Molecular Weight : 490.633

  • PUBCHEM ID : 72948694

  • Volume : 20mg

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Catalogue Number

BD-D0594

Analysis Method

HPLC,NMR,MS

Specification

HPLC≥98%

Storage

2-8°C

Molecular Weight

490.633

Appearance

White crystalline powder

Botanical Source

Vitex negundo L.;Radix Cynanchi Auriculati /Cynanchum caudatum

Structure Type

Steroids

Category

Standards;Natural Pytochemical;API

SMILES

CC(C)C(=CC(=O)OC1CC2C3(CCC(CC3=CCC2(C4(C1(C(CC4)(C(=O)C)O)C)O)O)O)C)C

Synonyms

2-Pentenoic acid, 3,4-dimethyl-, (3β,12β,14β)-3,8,14,17-tetrahydroxy-20-oxopregn-5-en-12-yl ester, (2E)-/(3β,12β,14β)-3,8,14,17-Tetrahydroxy-20-oxopregn-5-en-12-yl (2E)-3,4-dimethyl-2-pentenoate

IUPAC Name

[(3S,8S,9R,10R,12R,13S,14R,17R)-17-acetyl-3,8,14,17-tetrahydroxy-10,13-dimethyl-1,2,3,4,7,9,11,12,15,16-decahydrocyclopenta[a]phenanthren-12-yl] (E)-3,4-dimethylpent-2-enoate

Density

1.3±0.1 g/cm3

Solubility

Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.

Flash Point

197.5±25.0 °C

Boiling Point

617.9±55.0 °C at 760 mmHg

Melting Point

InChl

InChI=1S/C28H42O7/c1-16(2)17(3)13-23(31)35-22-15-21-24(5)9-8-20(30)14-19(24)7-10-27(21,33)28(34)12-11-26(32,18(4)29)25(22,28)6/h7,13,16,20-22,30,32-34H,8-12,14-15H2,1-6H3/b17-13+/t20-,21+,22+,24-,25+,26-,27-,28+/m0/s1

InChl Key

VWLXIXALPNYWFH-UBHIOMQOSA-N

WGK Germany

RID/ADR

HS Code Reference

2933990000

Personal Projective Equipment

Correct Usage

For Reference Standard and R&D, Not for Human Use Directly.

Meta Tag

provides coniferyl ferulate(CAS#:38395-02-7) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of coniferyl ferulate are included as well.>> amp version: coniferyl ferulate

No Technical Documents Available For This Product.

PMID

27910937

Abstract

In this study, the feasibility of biohydrogen production from enzymatic hydrolysis of food waste was investigated. Food waste (solid-to-liquid ratio of 10%, w/v) was first hydrolyzed by commercial glucoamylase to release glucose (24.35 g/L) in the food waste hydrolysate. Then, the obtained food waste hydrolysate was used as substrate for biohydrogen production in the batch and continuous (continuous stirred tank reactor, CSTR) systems. It was observed that the maximum cumulative hydrogen production of 5850 mL was achieved with a yield of 245.7 mL hydrogen/g glucose (1.97 mol hydrogen/mol glucose) in the batch system. In the continuous system, the effect of hydraulic retention time (HRT) on biohydrogen production from food waste hydrolysate was investigated. The optimal HRT obtained from this study was 6 h with the highest hydrogen production rate of 8.02 mmol/(h·L). Ethanol and acetate were the major soluble microbial products with low propionate production at all HRTs. Enzymatic hydrolysis of food waste could effectively accelerate hydrolysis speed, improve substrate utilization rate and increase hydrogen yield.

Title

Biohydrogen production from enzymatic hydrolysis of food waste in batch and continuous systems

Author

Wei Han,1 Yingting Yan,1 Yiwen Shi,1 Jingjing Gu,1 Junhong Tang,a,1 and Hongting Zhao1

Publish date

2016 Dec 2

PMID

22064997

Abstract

In the title salt, C15H17N4O4S2 +·Cl−, the chloride anion is disordered over two positions with occupancies of 0.776 (6) and 0.224 (6). The cation adopts an L shape and the dihedral angle between the benzene rings is 82.5 (3)°. In the crystal, inversion dimers of cations linked by pairs of N—H⋯N hydrogen bonds occur, with the bond arising from the protonated N atom. The cationic dimers are linked into chains via the disordered chloride ions by way of N—H⋯Cl hydrogen bonds and N—H⋯O, C—H⋯O and C—H⋯Cl inter­actions also occur, which help to consolidate the three-dimensional network.

Title

5,13-Disulfamoyl-1,9-diazatetracyclo[7.7.1.02,7.010,15]heptadeca-2(7),3,5,10,12,14-hexaen-1-ium chloride

Author

Yichao Xu,a Shouwen Jin,a,* Jianlong Zhu,a YingJia Liu,a and ChuanChuan Shia

Publish date

2011 Sep 30

PMID

24107555

Abstract

Background
Patients with non-ST-segment elevation acute coronary syndrome (NSTE-ACS) have varying degrees of salvageable myocardium at risk of irreversible injury. We hypothesized that a novel model of NSTE-ACS produces acute myocardial injury, measured by increased T2 cardiovascular magnetic resonance (CMR), without significant necrosis by late gadolinium enhancement (LGE).

Methods
In a canine model, partial coronary stenosis was created and electrodes placed on the epicardium. Myocardial T2, an indicator of at-risk myocardium, was measured pre- and post-tachycardic pacing.

Results
Serum troponin-I (TnI) was not detectable in unoperated sham animals but averaged 1.97 ± 0.72 ng/mL in model animals. Coronary stenosis and pacing produced significantly higher T2 in the affected vs. the remote myocardium (53.2 ± 4.9 vs. 43.6 ± 2.8 ms, p < 0.01) with no evident injury by LGE. Microscopy revealed no significant irreversible cellular injury. Relative respiration rate (RRR) of affected vs. remote myocardial tissue was significantly lower in model vs. sham animals (0.72 ± 0.07 vs. 1.04 ± 0.07, p < 0.001). Lower RRR corresponded to higher final TnI levels (R2 = 0.83, p = 0.004) and changes in CaMKIID and mitochondrial gene expression. Conclusions A large animal NSTE-ACS model with mild TnI elevation and without ST elevation, similar to the human syndrome, demonstrates signs of acute myocardial injury by T2-CMR without significant irreversible damage. Reduced tissue respiration and associated adaptations of critical metabolic pathways correspond to increased myocardial injury by serum biomarkers in this model. T2-CMR as a biomarker of at-risk but salvageable myocardium warrants further consideration in preclinical and clinical studies of NSTE-ACS.

KEYWORDS

Myocardial ischemia, Oxygen consumption, Cardiovascular magnetic resonance, Canine model, Mitochondria

Title

At-risk but viable myocardium in a large animal model of non ST-segment elevation acute coronary syndrome: cardiovascular magnetic resonance with ex vivo validation

Author

Henry Chang,1 Tam Tran,1 George E Billman,1,2 Mark W Julian,1 Robert L Hamlin,3 Orlando P Simonetti,1,4,5 Giuseppe Ambrosio,6 Peter B Baker, III,1,7 Guohong Shao,1 Elliott D Crouser,1,8 and Subha V Ramancorresponding author1,4,5

Publish date

2013 Oct 9.


Description :

Caudatin is a steroidal cmpound found in Cynanchum auriculatum, causes cell cycle arrest and induces apoptosis, with anti-cancer and antiangiogenic properties[1].