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Cimidahurinine

$1,200 $1,080

  • Brand : BIOFRON

  • Catalogue Number : BN-O1717

  • Specification : 98%(HPLC)

  • CAS number : 142542-89-0

  • Formula : C14H20O8

  • Molecular Weight : 316.3

  • PUBCHEM ID : 5315870

  • Volume : 5MG

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Catalogue Number

BN-O1717

Analysis Method

HPLC,NMR,MS

Specification

98%(HPLC)

Storage

-20℃

Molecular Weight

316.3

Appearance

Oil

Botanical Source

This product is isolated and purified from the roots of Cimicifuga foetida

Structure Type

Phenols

Category

Standards;Natural Pytochemical;API

SMILES

C1=CC(=C(C=C1CCO)OC2C(C(C(C(O2)CO)O)O)O)O

Synonyms

osmanthuside F/2-Hydroxy-5-(2-hydroxyethyl)phenyl β-D-glucopyranoside/β-D-Glucopyranoside, 2-hydroxy-5-(2-hydroxyethyl)phenyl

IUPAC Name

(2S,3R,4S,5S,6R)-2-[2-hydroxy-5-(2-hydroxyethyl)phenoxy]-6-(hydroxymethyl)oxane-3,4,5-triol

Applications

Density

1.5±0.1 g/cm3

Solubility

Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.

Flash Point

323.5±31.5 °C

Boiling Point

611.2±55.0 °C at 760 mmHg

Melting Point

InChl

InChI=1S/C14H20O8/c15-4-3-7-1-2-8(17)9(5-7)21-14-13(20)12(19)11(18)10(6-16)22-14/h1-2,5,10-20H,3-4,6H2/t10-,11-,12+,13-,14-/m1/s1

InChl Key

QOGCASCQGJEYDO-RKQHYHRCSA-N

WGK Germany

RID/ADR

HS Code Reference

2933990000

Personal Projective Equipment

Correct Usage

For Reference Standard and R&D, Not for Human Use Directly.

Meta Tag

provides coniferyl ferulate(CAS#:142542-89-0) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of coniferyl ferulate are included as well.>> amp version: coniferyl ferulate

No Technical Documents Available For This Product.

PMID

32245245

Abstract

This study evaluated bioactivity-guided fractionation as a means to identify therapeutic phytochemicals from Pyracantha angustifolia that can attenuate melanogenesis and oxidation. Seven compounds with inhibitory effects on melanin production and tyrosinase (TYR) activity, and ABTS and DPPH radical-scavenging activities, which have not been reported as whitening materials, were isolated from the n-butanol fraction from P. angustifolia leaves (PAL). Among the seven compounds, p-hydroxybenzoic acid β-d-glucosylester (HG), and cimidahurinine (CH) had strong inhibitory effects on melanin production and TYR activity, as well as ABTS and DPPH radical-scavenging activities. Western blot analysis showed that HG and CH suppressed tyrosinase-related protein (TYRP)-1 and TYRP-2 expression. Moreover, HG and CH inhibited reactive oxygen species (ROS) generation in tert-butyl hydroperoxide (t-BHP)-treated B16F10 cells. These results suggest that P. angustifolia containing active compounds, such as HG and CH, is a potent therapeutic candidate for the development of hypopigmenting agents.

KEYWORDS

Cimidahurinine; Pyracantha angustifolia; antioxidant; melanin; p-Hydroxybenzoic acid β-d-glucosylester; tyrosinase

Title

p-Hydroxybenzoic Acid β-d-Glucosyl Ester and Cimidahurinine with Antimelanogenesis and Antioxidant Effects from Pyracantha angustifolia via Bioactivity-Guided Fractionation.

Author

Shim SY1, Lee YE2, Song HY2, Lee M2.

Publish date

2020 Mar 21