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Cinnamic acid

$225

  • Brand : BIOFRON

  • Catalogue Number : BF-C1011

  • Specification : 98%

  • CAS number : 621-82-9

  • Formula : C9H8O2

  • Molecular Weight : 148.16

  • PUBCHEM ID : 444539

  • Volume : 20mg

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Catalogue Number

BF-C1011

Analysis Method

HPLC,NMR,MS

Specification

98%

Storage

2-8°C

Molecular Weight

148.16

Appearance

White crystalline powder

Botanical Source

Lindera aggregata,Scrophularia ningpoensis,Chaenomeles speciosa,Cynanchum paniculatum,Cremastra appendiculata

Structure Type

Phenylpropanoids

Category

Standards;Natural Pytochemical;API

SMILES

C1=CC=C(C=C1)C=CC(=O)O

Synonyms

(E)-3-Phenylprop-2-enoic acid/Propenoic acid, 3-phenyl-, (trans)-/Cinnamic acid/(2E)-3-Phenylacrylic acid/trans-Cinnamic Acid/QV1U1R &&Trans or E Form/2-Propenoic acid, 3-phenyl-, (2E)-/4-09-00-02002 (Beilstein Handbook Reference)/trans-b-Carboxystyrene/2-Propenoicacid, 3-phenyl-

IUPAC Name

(E)-3-phenylprop-2-enoic acid

Applications

Cinnamic acid has potential use in cancer intervention, with IC50s of 1-4.5 mM in glioblastoma, melanoma, prostate and lung carcinoma cells.

Density

1.2±0.1 g/cm3

Solubility

Methanol

Flash Point

189.5±9.6 °C

Boiling Point

265.0±0.0 °C at 760 mmHg

Melting Point

133ºC

InChl

InChI=1S/C9H8O2/c10-9(11)7-6-8-4-2-1-3-5-8/h1-7H,(H,10,11)/b7-6+

InChl Key

WBYWAXJHAXSJNI-VOTSOKGWSA-N

WGK Germany

RID/ADR

HS Code Reference

2916390000

Personal Projective Equipment

Correct Usage

For Reference Standard and R&D, Not for Human Use Directly.

Meta Tag

provides coniferyl ferulate(CAS#:621-82-9) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of coniferyl ferulate are included as well.>> amp version: coniferyl ferulate

PMID

29262714

Abstract

To elucidate the physiological mechanism of salt stress mitigated by cinnamic acid (CA) and fish flour (FF) pretreatment, wheat was pretreated with 20, 50 and 100 ppm CA and 1 g/10 mL FF for 2 d and was then cultivated. We investigated whether exogenous CA + FF could protect wheat from salt stress and examined whether the protective effect was associated with the regulation of seed vigor, antioxidant defense systems, phenolic biosynthesis and lipid peroxidation. At 2 days exogenous CA did not influence seed vigor. Salt stress increased the phenolic biosynthesis, but the CA + FF-combined pretreatment enhanced the phenolic biosynthesis even more under salt stress and decreased lipid peroxidation to some extent, enhancing the tolerance of wheat to salt stress.

KEYWORDS

Cinnamic acid; fish flour; phenolic biosynthesis; salinity stress; wheat

Title

Cinnamic acid and fish flour affect wheat phenolic acids and flavonoid compounds, lipid peroxidation, proline levels under salt stress.

Author

Karadag B1, Yucel NC1.

Publish date

2017 Dec

PMID

32163810

Abstract

In this work, we present the synthesis and characterization of five new ruthenium compounds with general formula [Ru(L)(dppb)(bipy)]PF6, where L = cinnamic acid derivatives, dppb = 1,4-bis(diphenylphosphino)butane and bipy = 2,2′-bipyridine. The cytotoxicity of the complexes was evaluated against human breast tumor cells from the lines MCF-7, MDA-MB-231 and in human (MCF-10A) or mouse (L929) non-tumor cells. Complexes Ru(L4)(dppb)(bipy)]PF6 (4) (L4 = 4-hydroxycinnamic acid) and [Ru(L5)(dppb)(bipy)]PF6 (5) (L5 = 3,4-dihydroxycinnamic acid) were the most selective, presenting the highest values of selectivity indexes besides inhibited some processes related to tumor progression in vitro, such as invasion, migration, and adhesion in the MDA-MB-231 cell line. In addition, the complexes 4 and 5 were able to interact with Bovine Serum Albumin (BSA) and complex 5 showed antioxidant activity.

Copyright © 2020 Elsevier Inc. All rights reserved.

KEYWORDS

Antimetastatic potential; Antioxidant activity; Cinnamic acids; Ruthenium complexes

Title

Evaluation of the biological potential of ruthenium(II) complexes with cinnamic acid.

Author

Graminha AE1, Honorato J2, Dulcey LL3, Godoy LR3, Barbosa MF4, Cominetti MR3, Menezes AC5, Batista AA6.

Publish date

2020 May