Catalogue Number
BN-O1560
Analysis Method
HPLC,NMR,MS
Specification
98%(HPLC)
Storage
-20℃
Molecular Weight
274.3
Appearance
Powder
Botanical Source
This product is isolated and purified from the herbs of Murraya paniculata (L.) Jack
Structure Type
Coumarins
Category
Standards;Natural Pytochemical;API
SMILES
CC(=CCC1=C(C=C(C2=C1OC(=O)C=C2)OC)OC)C
Synonyms
5,7-Dimethoxy-8-(3-methyl-2-buten-1-yl)-2H-chromen-2-one/Coumarrayin/2H-1-Benzopyran-2-one, 5,7-dimethoxy-8-(3-methyl-2-buten-1-yl)-/coumurrayin
IUPAC Name
5,7-dimethoxy-8-(3-methylbut-2-enyl)chromen-2-one
Density
1.1±0.1 g/cm3
Solubility
Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Flash Point
195.7±28.8 °C
Boiling Point
440.0±45.0 °C at 760 mmHg
Melting Point
InChl
InChI=1S/C16H18O4/c1-10(2)5-6-11-13(18-3)9-14(19-4)12-7-8-15(17)20-16(11)12/h5,7-9H,6H2,1-4H3
InChl Key
CPXPWRXPEOMRNV-UHFFFAOYSA-N
WGK Germany
RID/ADR
HS Code Reference
2932200000
Personal Projective Equipment
Correct Usage
For Reference Standard and R&D, Not for Human Use Directly.
Meta Tag
provides coniferyl ferulate(CAS#:17245-25-9) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of coniferyl ferulate are included as well.>> amp version: coniferyl ferulate
No Technical Documents Available For This Product.
29086834
Background
Toddalia asiatica root bark as an effective hemostatic natural medicine or Chinese materia medica was applied in China for long history, its complex drug action mechanisms and unclear substance basis have been constraining the development of this drug.
Results
An intelligentized strategy by LC-ESI Q-TOF MSE was presented in this study for rapid identification of hemostatic chemical constituents from this natural medicine. Chromatographic separation was performed on a C18 column (150 mm × 2.1 mm, 1.8 μm), the MSE data in both negative and positive ion modes were acquired to record the high-accuracy MS and MS/MS data of all precursor ions. To reduce the false positive identifications, structural confirmation was conducted by comparison with the isolated reference standards (tR and MS, MS/MS data) or matching with natural product databases. Bioassay-guided fractionation of the extract of T. asiatica root bark was also carried out.
Conclusions
As a consequence, 31 natural compounds in T. asiatica root bark got putatively characterized. There were four main coumarins, isopimpinellin (Cp.23), pimpinellin (Cp.24), coumurrayin (Cp.30) and phellopterin (Cp.34) isolated and identified from T. asiatica root bark. The present study provided candidate strategy that helps to effectively identify the primary natural compounds of TCM or other complex natural medicines, and then promote development and application of natural medicines and their medicinal resources.
Q-TOF, MSE, Toddalia asiatica root bark, Qualitative analysis, Chemical database
Hemostatic chemical constituents from natural medicine Toddalia asiatica root bark by LC-ESI Q-TOF MSE
Xiaoyan Zhang,#1 Wenbo Sun,#1 Zhou Yang,2 Yan Liang,1 Wei Zhou,corresponding author1 and Lei Tangcorresponding author1
2017;
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