2-N-cyclopropyl-1,3,5-triazine-2,4,6-triamine/Larvadex/Vetrazine/N2-cyclopropyl-1,3,5-triazine-2,4,6-triamine/N-Cyclopropyl-1,3,5-triazine-2,4,6-triamine/Vetrazin/2,4-diamino-6-cyclopropylamino-1,3,5-triazine/Azimethiphos/Neporex/2,4-diamino-6-cyclopropylamino-s-triazine/Cyromazine/1,3,5-Triazine-2,4,6-triamine, N-cyclopropyl-/N1-cyclopropyl-1,3,5-triazine-2,4,6-triamine/Cyclopropylmelamine/Cypromazine/Citation/Trigard/N CYCLOPROPYL 1,3,5 TRIAZINE 2,4,6 TRIAMINE
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provides coniferyl ferulate(CAS#:66215-27-8) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of coniferyl ferulate are included as well.>> amp version: coniferyl ferulate
1994 Jun 17
Cyromazine in livestock products was determined using a validated LC-MS/MS method. There are three key points in our methods. First, the extraction was performed with two solutions, methanol and pH 3.0 McIlvaine buffer. The process was optimized for each type of sample. Secondly, cleanup was performed using a reversed-phase and strong cation exchange mixed-mode cartridge. The cartridge was washed with 0.14％ ammonium solution. Thirdly, the chromatographic separation was performed on an anion-cation exchange mode ODS column. There was no matrix effect on the extraction and determination for five livestock products. The quantification was carried out using an external standard calibration curve. This new method satisfies the Japanese guideline criteria. Recovery ranged from 77.2 to 92.1％, the relative standard deviation of repeatability （RSDr） was under 2.2％, and RSDwr was under 6.1％. Residual cyromazine was detected in raw milks and eggs.
LC-MS/MS; anion-cation exchange mode ODS column; cyromazine; livestock product; reversed-phase and strong cation exchange mix mode cartridge.
[Determination of Cyromazine in Livestock Products by LC-MS/MS on an Anion-Cation Exchange Mode ODS Column]
Yuki Okutomi 1, Hiroshi Hayashi 1, Yoko Matsushima 1, Yumi Ohba 1, Yukiko Nakagawa 1, Hiroshi Koike 1, Chieko Nagano 1, Kotaro Sekimura 1, Maki Kanda 1, Tsuneo Hashimoto 1
Providing guidance on the reasonable use of pesticide in agricultural production is of particular importance for ensuring food safety. In the present study, a field trial was performed to study the dissipation and accumulative pattern of cyromazine (CA) and its metabolite in Agaricus bisporus (A. bisporus) cultivation. An ultra-performance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS) method was first developed and validated for the determination of CA and melamine (MEL) in the casing soil and fruiting body. During the cultivation period, the dissipation rates of CA in the casing soil were between 51.57 and 63.48% at three dose groups. The fruiting body presented higher accumulation ability for MEL compared with CA. The terminal residues of MEL never exceeded the maximum residue limits (MRLs) in food. In addition, the intake health risk from the CA and MEL residues in the fruiting body were negligible to humans. This study will help to provide valuable guidance on the application strategies of CA in A. bisporus cultivation.
Agaricus bisporus; Bioconcentration; Cyromazine and melamine; Dietary risk assessment; Dissipation.
Liquid Chromatography-Mass Spectrometry Method for Evaluating the Dissipation Dynamics of Cyromazine and Its Metabolite in Agaricus Bisporus and Dietary Risk Assessment
Zhiyong Zhao 1, Lei Chen 1, Bing Bai 1, Xianli Yang 1, Yanglan Tan 2, Jianhua Wang 1, Xiaoyan Zhao 3, Changyan Zhou 4