We Offer Worldwide Shipping
Login Wishlist

Cytosine

$52

  • Brand : BIOFRON

  • Catalogue Number : BD-P0687

  • Specification : 98.0%(HPLC)

  • CAS number : 71-30-7

  • PUBCHEM ID : 597

  • Volume : 100mg

Available on backorder

Quantity
Checkout Bulk Order?

Catalogue Number

BD-P0687

Analysis Method

HPLC,NMR,MS

Specification

98.0%(HPLC)

Storage

2-8°C

Molecular Weight

Appearance

White crystalline powder

Botanical Source

Structure Type

Nucleosides/Nucleotide

Category

Standards;Natural Pytochemical;API

SMILES

C1=C(NC(=O)N=C1)N

Synonyms

Cytosin/Cytosinimine/Cytosine/4-aminopyrimidin-2-one/Cyt/Lamivudine Impurity 5/6-Aminopyrimidin-2(1H)-one

IUPAC Name

6-amino-1H-pyrimidin-2-one

Applications

6-Aminopyrimidin-2(1H)-one is an organic compound that belongs to the class known as pyrimidones.

Density

1.6±0.1 g/cm3

Solubility

Water; DMSO

Flash Point

223.4ºC

Boiling Point

445.8ºC at 760 mmHg

Melting Point

>300 °C(lit.)

InChl

InChl Key

WGK Germany

RID/ADR

HS Code Reference

2933590000

Personal Projective Equipment

Correct Usage

For Reference Standard and R&D, Not for Human Use Directly.

Meta Tag

provides coniferyl ferulate(CAS#:71-30-7) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of coniferyl ferulate are included as well.>> amp version: coniferyl ferulate

No Technical Documents Available For This Product.

PMID

28668047

Abstract

Epigenetic modifications of cytosine have been found to influence differently in many processes in biological systems. In order to investigate the differences in electron attachment to different epigenetic modifications of cytosine, we reported the A″ component of the integral cross section of electron scattering by cytosine (C) and its epigenetic modifications 5-methylcytosine (5mC), 5-hydroxymethylcytosine (5hmC), 5-formylcytosine (5fC), and 5-carboxylcytosine (5caC). Our results were obtained with the Schwinger multichannel method with pseudopotentials in the static-exchange (SE) and static-exchange plus polarization (SEP) approximations. In addition to the scattering results, we present electron attachment energies obtained through an empirical scaling relation for the five molecules. We observed three π* resonances for C, 5mC, and 5hmC and four for 5fC and 5caC, in both SE and SEP approximations. The cross sections show that the π* resonances of 5mC and 5hmC are located at higher energies than the resonances of C, while the resonances of 5fC and 5caC are located at lower energies. In order to investigate this shift in the resonances’ positions, we analyzed the π* lowest-lying orbitals and the electronic density over the molecules. Using the inductive and mesomeric effects, we were able to analyze the influence of each substituent over the molecule and on the resonances’ positions.

Title

Substituents' effect in electron attachment to epigenetic modifications of cytosine.

Author

Nunes FB1, Bettega MHF1, Sanchez SD1.

Publish date

2017 Jun 28

PMID

32291894

Title

Cytosine drives evolution of SARS-CoV-2.

Author

Danchin A1, Marliere P2.

Publish date

2020 Apr 14

PMID

32251591

Abstract

The decay mechanism of S0 → S1 excited cytosine (Cyt) and the effect of substitution are studied combining jet-cooled spectroscopy (nanosecond resonant two-photon ionization (R2PI) and picosecond lifetime measurements) with CASPT2//CASSCF computations for eight derivatives. For Cyt and five derivatives substituted at N1, C5, and C6, rapid internal conversion sets in at 250-1200 cm-1 above the 000 bands. The break-off in the spectra correlates with the calculated barriers toward the “C5-C6 twist” conical intersection, which unambiguously establishes the decay mechanism at low S1 state vibrational energies. The barriers increase with substituents that stabilize the charge shifts at C4, C5, and C6 following (1ππ*) excitation. The R2PI spectra of the clamped derivatives 5,6-trimethyleneCyt (TMCyt) and 1-methyl-TMCyt (1M-TMCyt), which decay along an N3 out-of-plane coordinate, extend up to +3500 and +4500 cm-1.

Title

Locating Cytosine Conical Intersections by Laser Experiments and Ab Initio Calculations.

Author

Trachsel MA1, Blaser S1, Lobsiger S1, Siffert L1, Frey HM1, Blancafort L2, Leutwyler S1.

Publish date

2020 Apr 10