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Ellagic acid

$43

  • Brand : BIOFRON

  • Catalogue Number : BF-E3010

  • Specification : 98%

  • CAS number : 476-66-4

  • Formula : C14H6O8

  • Molecular Weight : 302.19

  • PUBCHEM ID : 5281855

  • Volume : 100mg

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Catalogue Number

BF-E3010

Analysis Method

HPLC,NMR,MS

Specification

98%

Storage

-20℃

Molecular Weight

302.19

Appearance

White crystalline powder

Botanical Source

Punica granatum,Rhodiola crenulata,Phyllanthus emblica,Acacia catechu,Centella asiatica

Structure Type

Tannins

Category

Standards;Natural Pytochemical;API

SMILES

C1=C2C3=C(C(=C1O)O)OC(=O)C4=CC(=C(C(=C43)OC2=O)O)O

Synonyms

lagistase/2,3,7,8-Tetrahydroxychromeno[5,4,3-cde]chromene-5,10-dione/Ellagic acid/Elllagic Acid/elagostasine/eleagicacid/Ellagic/BENZOARIC ACID

IUPAC Name

6,7,13,14-tetrahydroxy-2,9-dioxatetracyclo[6.6.2.04,16.011,15]hexadeca-1(15),4,6,8(16),11,13-hexaene-3,10-dione

Density

2.1±0.1 g/cm3

Solubility

DMSO; DMF

Flash Point

310.1±26.4 °C

Boiling Point

796.5±60.0 °C at 760 mmHg

Melting Point

≥350 °C

InChl

InChl Key

WGK Germany

RID/ADR

HS Code Reference

2932200000

Personal Projective Equipment

Correct Usage

For Reference Standard and R&D, Not for Human Use Directly.

Meta Tag

provides coniferyl ferulate(CAS#:476-66-4) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of coniferyl ferulate are included as well.>> amp version: coniferyl ferulate

PMID

29141541

Abstract

Background: Naturally occurring polyphenols are the subject of increasing attention due to their potent antioxidant activity and their marked effects on the prevention of various oxidative stress-associated diseases such as cancer. Ellagic acid (EA) is an herbal polyphenol that is structurally a condensed dimer of gallic acid.
Methods: This review aims to provide a comprehensive and updated overview on the biological activities of EA and potential therapeutic applications.
Results: EA is found in fruits and nuts, either in the combined form with hexahydroxydiphenic acid or in the bound form (ellagitannins). EA exhibits many biological properties such as antioxidant, anti-diabetic, anticancer and apoptosis-inducing activities. These biological and pharmacological properties are relevant to the treatment of several human diseases.
Conclusion: Owing to its multiple mechanisms of action, EA represents a potential therapeutic agent against human diseases particularly cancer.

KEYWORDS

olyphenol; antioxidant; ellagic acid; gallic acid; pharmacology; phytomedicine..

Title

Ellagic Acid: A Logical Lead for Drug Development?

Publish date

2018

PMID

27671829

Abstract

Ellagic acid is a natural anti-oxidant phenol found in numerous fruits and vegetables, in particular pomegranate, persimmon, raspberry, black raspberry, strawberry, peach, plumes, nuts (walnuts, almonds), and wine. The anti-proliferative and anti-oxidant properties of ellagic acid have prompted research into its potential health benefits. The aim of this chapter will be to summarize potential benefits of ellagic acid supplementation in chronic diseases.

KEYWORDS

Cancer; Chronic inflammation; Diabetes; Ellagic acid.

Title

Ellagic Acid and Its Role in Chronic Diseases

Author

Giuseppe Derosa 1 2 3 4 , Pamela Maffioli 5 6 , Amirhossein Sahebkar 7 8

Publish date

2016

PMID

29388153

Abstract

Oxidative stress is a biological condition produced by a variety of factors, causing several chronic diseases. Oxidative stress was, therefore, treated with natural antioxidants, such as ellagic acid (EA). EA has a major role in protecting against different diseases associated with oxidative stress. This review critically discussed the antioxidant role of EA in biological systems. The in vitro and in vivo studies have confirmed the protective role of EA in suppressing oxidative stress. The review also discussed the mechanism of EA in suppressing of oxidative stress, which showed that EA activates specific endogenous antioxidant enzymes and suppresses specific genes responsible for inflammation, diseases, or disturbance of biochemical systems. The amount of EA used and duration, which plays a significant role in the treatment of oxidative stress has been discussed. In conclusion, EA is a strong natural antioxidant, which possesses the suppressing power of oxidative stress in biological systems.
Keywords: Antioxidant; Ellagic acid; In vitro models; In vivo studies; Oxidative stress.

Title

Ellagic Acid in Suppressing in Vivo and in Vitro Oxidative Stresses

Author

Alam Zeb 1

Publish date

2018 Nov


Description :

Ellagic acid is a natural antioxidant, and acts as a potent and ATP-competitive CK2 inhibitor, with an IC50 of 40 nM and a Ki of 20 nM.