Orange crystalline powder
Periploca forrestii,Sarcandra glabra,Rheum palmatum,Reynoutria japonica,Chrysanthemum morifolium
Methanol; DMF; DMSO
586.9±39.0 °C at 760 mmHg
255 °C (dec.)(lit.)
HS Code Reference
Personal Projective Equipment
For Reference Standard and R&D, Not for Human Use Directly.
provides coniferyl ferulate(CAS#:518-82-1) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of coniferyl ferulate are included as well.>> amp version: coniferyl ferulate
Emodin is a natural anthraquinone derivative that occurs in many widely used Chinese medicinal herbs, such as Rheum palmatum, Polygonum cuspidatum and Polygonum multiflorum. Emodin has been used as a traditional Chinese medicine for over 2000 years and is still present in various herbal preparations. Emerging evidence indicates that emodin possesses a wide spectrum of pharmacological properties, including anticancer, hepatoprotective, antiinflammatory, antioxidant and antimicrobial activities. However, emodin could also lead to hepatotoxicity, kidney toxicity and reproductive toxicity, particularly in high doses and with long-term use. Pharmacokinetic studies have demonstrated that emodin has poor oral bioavailability in rats because of its extensive glucuronidation. This review aims to comprehensively summarize the pharmacology, toxicity and pharmacokinetics of emodin reported to date with an emphasis on its biological properties and mechanisms of action.
Copyright © 2016 John Wiley & Sons, Ltd.
emodin; mechanisms; pharmacokinetics; pharmacology; toxicology
Emodin: A Review of its Pharmacology, Toxicity and Pharmacokinetics.
Dong X1, Fu J1, Yin X1, Cao S1, Li X1, Lin L1; Huyiligeqi, Ni J1.
Diseases, such as heart disease, stroke, cancer, respiratory diseases, and diabetes, are by far the leading cause of mortality in the world, representing 60 % of all deaths. Although substantial medical advances have been made and many therapeutic approaches proposed yet traditional medicine and medicinal plants find an important place in therapy. They have been providing invaluable solutions to the various health problems. Emodin (1,3,8-trihydroxy-6-methylanthraquinone) is a natural anthraquinone derivative found in various Chinese medicinal herbs. Traditionally, it has been used as an active constituent of many herbal laxatives. However, in the last few years, significant progress has been made in studying the biological effects of emodin at cellular and molecular levels and it is emerging as an important therapeutic agent. This review provides an overview of the modulatory effects of emodin in various diseases and cell signaling pathways, which may have important implications in its future clinical use.
Anthraquinone; Bioavailability; Cancer; Chemosesitizer; Emodin; Radiosensitizer
Emodin and Its Role in Chronic Diseases.
Monisha BA1, Kumar N2, Tiku AB3.
In the original publication of the article.
Emodin alleviated pulmonary inflammation in rats with LPS-induced acute lung injury through inhibiting the mTOR/HIF-1α/VEGF signaling pathway. [Inflamm Res. 2020]
Correction to: Emodin alleviated pulmonary inflammation in rats with LPS-induced acute lung injury through inhibiting the mTOR/HIF-1α/VEGF signaling pathway.
Li X1,2, Shan C1,2, Wu Z1,2, Yu H1,2, Yang A3,4, Tan B5.
2020 Apr 3