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Endothal

$144

  • Brand : BIOFRON

  • Catalogue Number : BD-D1281

  • Specification : 98%(HPLC)

  • CAS number : 145-73-3

  • Formula : C8H10O5

  • Molecular Weight : 186.16

  • PUBCHEM ID : 3225

  • Volume : 20MG

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Catalogue Number

BD-D1281

Analysis Method

HPLC,NMR,MS

Specification

98%(HPLC)

Storage

2-8°C

Molecular Weight

186.16

Appearance

Powder

Botanical Source

Structure Type

Category

Standards;Natural Pytochemical;API

SMILES

C1CC2C(C(C1O2)C(=O)O)C(=O)O

Synonyms

aquatholplus/7-oxa-bicyclo[2.2.1]heptane-2,3-dicarboxylic acid/7-Oxabicyclo[2.2.1]heptane-2,3-dicarboxylicacid/Aquathol/Hydout/7-oxabicyclo[2.2.1]heptane-2,3-dicarboxylic acid/ENDOTHAL/ACCELERATE/Niagrathal/Hydrothol/Hydrothal/(1Ξ,2Ξ,3Ξ,4Ξ)-7-oxabicyclo[2.2.1]heptane-2,3-dicarboxylic acid/ENDOTHALL/Emdothal

IUPAC Name

7-oxabicyclo[2.2.1]heptane-2,3-dicarboxylic acid

Applications

Density

1.431

Solubility

Flash Point

190.5ºC

Boiling Point

350ºC(e)

Melting Point

144ºC

InChl

InChl Key

WGK Germany

RID/ADR

HS Code Reference

2932990000

Personal Projective Equipment

Correct Usage

For Reference Standard and R&D, Not for Human Use Directly.

Meta Tag

provides coniferyl ferulate(CAS#:145-73-3) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of coniferyl ferulate are included as well.>> amp version: coniferyl ferulate

No Technical Documents Available For This Product.

PMID

2955551

Abstract

Endothal and cantharidic acid were administered intraperitoneally to mice at 75 and 10 mg/kg, respectively, to compare their acute toxicity on liver tissue in vivo. Within 45 min both treatments caused extreme liver enlargement and congestion. Hepatic glycogenolysis was increased as evidenced by elevations in blood glucose and hepatic glycogen phosphorylase levels and by corresponding reductions in hepatic glycogen content and glycogen synthase activity. Endothal decreased hepatic ATP concentrations, although neither compound altered mitochondrial Mg2+-ATPase activity. Microsomal Mg2+-ATPase levels, however, were reduced by both treatments. There were no indications that reactive intermediates were involved in the toxicity of either compound. The results show that endothal and cantharidic acid act directly and cause similar biochemical changes in mouse liver in vivo.

Title

Comparison of the acute toxicity of endothal and cantharidic acid on mouse liver in vivo.

Author

Graziano MJ, Casida JE.

Publish date

1987 Jul