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Episappanol

$1,600

  • Brand : BIOFRON

  • Catalogue Number : BN-O2106

  • Specification : 98%(HPLC)

  • CAS number : 111254-18-3

  • Formula : C16H16O6

  • Molecular Weight : 304.29

  • PUBCHEM ID : 13846650

  • Volume : 20mg

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Quantity
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Catalogue Number

BN-O2106

Analysis Method

Specification

98%(HPLC)

Storage

2-8°C

Molecular Weight

304.29

Appearance

Botanical Source

Structure Type

Category

SMILES

C1C(C(C2=C(O1)C=C(C=C2)O)O)(CC3=CC(=C(C=C3)O)O)O

Synonyms

epi-Sappanol/(3R,4R)-3-(3,4-Dihydroxybenzyl)-3,4,7-chromanetriol/2H-1-Benzopyran-3,4,7-triol, 3-[(3,4-dihydroxyphenyl)methyl]-3,4-dihydro-, (3R,4R)-

IUPAC Name

(3R,4R)-3-[(3,4-dihydroxyphenyl)methyl]-2,4-dihydrochromene-3,4,7-triol

Applications

Density

1.6±0.1 g/cm3

Solubility

Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.

Flash Point

306.5±30.1 °C

Boiling Point

583.1±50.0 °C at 760 mmHg

Melting Point

InChl

InChI=1S/C14H12N2/c1-3-7-13(8-4-1)11-15-16-12-14-9-5-2-6-10-14/h1-12H/b15-11+,16-12+

InChl Key

MPGFEHZDABUJFR-HZPDHXFCSA-N

WGK Germany

RID/ADR

HS Code Reference

Personal Projective Equipment

Correct Usage

For Reference Standard and R&D, Not for Human Use Directly.

Meta Tag

provides coniferyl ferulate(CAS#:111254-18-3) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of coniferyl ferulate are included as well.>> amp version: coniferyl ferulate

No Technical Documents Available For This Product.

PMID

24109218

Abstract

The complete sequence of retroperitoneal fibromatosis-associated herpesvirus Macaca nemestrina (RFHVMn), the pig-tailed macaque homolog of Kaposi’s sarcoma-associated herpesvirus (KSHV), was determined by next-generation sequence analysis of a Kaposi’s sarcoma (KS)-like macaque tumor. Colinearity of genes was observed with the KSHV genome, and the core herpesvirus genes had strong sequence homology to the corresponding KSHV genes. RFHVMn lacked homologs of open reading frame 11 (ORF11) and KSHV ORFs K5 and K6, which appear to have been generated by duplication of ORFs K3 and K4 after the divergence of KSHV and RFHV. RFHVMn contained positional homologs of all other unique KSHV genes, although some showed limited sequence similarity. RFHVMn contained a number of candidate microRNA genes. Although there was little sequence similarity with KSHV microRNAs, one candidate contained the same seed sequence as the positional homolog, kshv-miR-K12-10a, suggesting functional overlap. RNA transcript splicing was highly conserved between RFHVMn and KSHV, and strong sequence conservation was noted in specific promoters and putative origins of replication, predicting important functional similarities. Sequence comparisons indicated that RFHVMn and KSHV developed in long-term synchrony with the evolution of their hosts, and both viruses phylogenetically group within the RV1 lineage of Old World primate rhadinoviruses. RFHVMn is the closest homolog of KSHV to be completely sequenced and the first sequenced RV1 rhadinovirus homolog of KSHV from a nonhuman Old World primate. The strong genetic and sequence similarity between RFHVMn and KSHV, coupled with similarities in biology and pathology, demonstrate that RFHVMn infection in macaques offers an important and relevant model for the study of KSHV in humans.

Title

Next-Generation Sequence Analysis of the Genome of RFHVMn, the Macaque Homolog of Kaposi's Sarcoma (KS)-Associated Herpesvirus, from a KS-Like Tumor of a Pig-Tailed Macaque

Author

A. Gregory Bruce, Jonathan T. Ryan, Mathew J. Thomas, Xinxia Peng, Adam Grundhoff, Che-Chung Tsai, Timothy M. Rose

Publish date

2013 Dec;

PMID

25077058

Abstract

Introduction
Subdural hematoma (SDH) is a well described risk factor in the development of Status Epilepticus (SE), however the epidemiology of SE after SDH is unknown. In this study, we sought to determine the epidemiology of SE, the prevalence of risk factors, and impact on hospital mortality using a large administrative dataset.

Methods
Data was derived from the Nationwide Inpatient Sample from 1988 through 2011. We queried the NIS database for patients older than 18 years, with a diagnosis of SDH and SE. Diagnoses were defined by ICD 9 CM codes 432.1, 852.2, 852.3 and 345.3 for SE. Adjusted incidence rates of admission and prevalence proportions were calculated. Multivariate logistic models were then fitted to assess for the impact of status epilepticus on hospital mortality.

Results
Over the 23-year period, we identified more than 1,583,255 admissions with a diagnosis of SDH. The prevalence of SE in this cohort was 0.5% (7,421 admissions). The population adjusted incidence rate of admissions of SDH increased from 13/100,000 in 1988 to 38/100,000 in 2011. The prevalence of SE in SDH, increased from 0.5% in 1988 to 0.7% in 2011. In hospital mortality of patients with SDH and without SE decreased from 17.9% to 10.3% while in hospital mortality of patients with SDH and SE did not statistically change. Mortality increased over the same period (2.3/100,000 in 1988 to 3.9/100.000 in 2011) and the diagnosis of SE increased mortality in this cohort (OR 2.17, p < 0.0001). The risk of SE remained stable throughout the study period, but was higher among older patients, blacks, and in those with respiratory, metabolic, hematological, and renal system dysfunction. Conclusion Our study demonstrates that the incidence of admissions of SDH is increasing in the United States. Despite a decline in the overall SDH related mortality, SE increased the risk of in-hospital death in patients with a primary diagnosis of SDH.

KEYWORDS

Subdural hematoma, Status epilepticus, Risk factors, Mortality

Title

The epidemiology, risk factors, and impact on hospital mortality of status epilepticus after subdural hematoma in the United States

Author

Ali Seifi, Ali Akbar Asadi-Pooya, Kevin Carr, Mitchell Maltenfort, Mehrdad Emami, Rodney Bell, Michael Moussouttas, Moussa Yazbeck, Fred Rincon

Publish date

2014;

PMID

29805989

Abstract

A short overview of subterranean Balkan hydrobid genera, with special focus on genus Bythiospeum Bourguignat, 1892 and Iglica A.J. Wagner, 1928 is given. In addition, based on recently collected material in Montenegro (Vitoja Spring) and Albania (Krumë), five new species are described, namely: Bracenica vitojaensis n. sp., Islamia montenegrina n. sp., Lanzaia pesici n. sp., Bythiospeum szarowskae n. sp. and Pseudamnicola krumensis n. sp. The holotypes and paratypes are depicted. In addition a re-description of Bythiospeum gittenbergeri (A. & P.L. Reischutz, 2008) is given and the types of the Iglica spp. deposited in the NHMW are depicted, some of them for the first time.

KEYWORDS

Hydrobiid snails, new species, taxonomy, Western Balkan

Title

New records of subterranean and spring molluscs (Gastropoda: Hydrobiidae) from Montenegro and Albania with the description of five new species

Author

Peter Gloer, Jozef Grego, Zoltan Peter Eross, Zoltan Feher

Publish date

2018 May 23.