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Estrone

$78

  • Brand : BIOFRON

  • Catalogue Number : BF-E3007

  • Specification : 98%

  • CAS number : 53-16-7

  • Formula : C18H22O2

  • Molecular Weight : 270.37

  • PUBCHEM ID : 5870

  • Volume : 25mg

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Catalogue Number

BF-E3007

Analysis Method

HPLC,NMR,MS

Specification

98%

Storage

2-8°C

Molecular Weight

270.37

Appearance

White crystalline powder

Botanical Source

Structure Type

Others

Category

Standards;Natural Pytochemical;API

SMILES

CC12CCC3C(C1CCC2=O)CCC4=C3C=CC(=C4)O

Synonyms

Follestrine/Ovifollin/Folliculine/Estrone-A/Destrone/Thelestrin/Hormofollin/Oestrin/Femestrone/Cristallovar/E 1/Hormovarine/3-Hydroxyestra-1,3,5(10)-trien-17one/Theelin/Femidyn/Oestrone/Kestrone/Kolpon/Endofolliculina/Wynestron/Estrin/Folipex/Hiestrone/Tokokin/Disynformon/Ketohydroxyestrin/3-Hydroxy-1,3,5(10)-estratrien-17-one/3-Hydroxyoestra-1,3,5(10)-trien-17-one/Glandubolin/1,3,5(10)-Estratrien-3-ol-17-one/Folliculin/Estrusol/Estra-1(10),2,4-trien-17-one, 3-hydroxy-/Crinovaryl/Ketodestrin/Estrugenone/Folikrin/Fem-O-Gen/Menformon/Estron/OESTROFORM/estrol/Ketohydroxyoestrin/Oestroperos/Perlatan/1,3,5-ESTRATRIEN-3-OL-17-ONE/Estrona/Hormestrin/3-Hydroxyestra-1(10),2,4-trien-17-one/Estrone/Thelykinin/Folisan/Ketohydroxy-estratriene/Oestronum/Follicunodis

IUPAC Name

(8R,9S,13S,14S)-3-hydroxy-13-methyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-17-one

Density

1.2±0.1 g/cm3

Solubility

Methanol; Chloroform; Ethano

Flash Point

189.7±21.3 °C

Boiling Point

445.2±45.0 °C at 760 mmHg

Melting Point

258-260 °C(lit.)

InChl

InChl Key

WGK Germany

RID/ADR

HS Code Reference

2937230000

Personal Projective Equipment

Correct Usage

For Reference Standard and R&D, Not for Human Use Directly.

Meta Tag

provides coniferyl ferulate(CAS#:53-16-7) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of coniferyl ferulate are included as well.>> amp version: coniferyl ferulate

PMID

31760543

Abstract

In this study, the effect of biochar (BC) derived from Litchi chinensis Sonn. and its modification, including Ca-biochar (Ca-BC) and Fe-Mn-biochar (Fe-Mn-BC), on the transportation of oestrone (E1) in water and soil was investigated. Fe-Mn-BC showed better adsorption ability than other types of biochar (BC, Ca-BC) under different conditions (humic acid, pH, ionic strength) in an aqueous environment. The maximum mass of sorbent at 298 K increased from 1.12 mg g-1 (BC) to 4.18 mg g-1 (Fe-Mn-BC). Humic acid had a greater impact on aqueous E1 adsorption on these biochars than did the pH and ionic strength. Fe-Mn-BC as a soil amendment had a great control of E1 transport in soil, and no leachate of E1 was observed in the column experiment. E1 mobility showed strong retardation in amended soil with Ca-BC (Rf = 11.2) compared with raw soil (Rf = 7.1). These results suggested that Fe-Mn-BC was more effective in controlling E1 transportation, and Fe-Mn-BC could be used as an alternative and inexpensive adsorbent to reduce E1 contaminants from water and soil.

KEYWORDS

Adsorption; Advection-dispersion model; Modified biochars; Oestrone

Title

The characteristics of oestrone mobility in water and soil by the addition of Ca-biochar and Fe-Mn-biochar derived from Litchi chinensis Sonn.

Author

Tao HY1,2,3, Ge H1,2, Shi J4,5, Liu X6, Guo W7,8, Zhang M1,2, Meng Y9, Li XY3.

Publish date

2019 Nov 23

PMID

31634940

Abstract

OBJECTIVE:
To assess testicular endocrine function in the male donkey (Equus asinus) during the course of the year.

MATERIAL AND METHODS:
In 5 miniature and 4 standard donkey stallions, peripheral blood concentrations of testosterone (T), estrone (E1) and estrone sulfate (E1S) were determined using radioimmunoassay.

RESULTS:
There was a highly significant influence of the season (p < 0.0001) on the course of all 3 steroids. Values were low in November until January and high in April, May and June. As delineated by the measurement of E1 the breed also had an effect on the expression of seasonality. Mean T concentration (X̅g × SF ± 1) was 1.58 × 1.20 ± 1 ng/ml, values ranged between 0.39 and 5.95 ng/ml, which is approximately double the plasma T concentrations observed in horse stallions. As in horse stallions, E1 levels were only slightly above the detection limit of the assay (0.10-0.17 ng/ml). Mean E1S concentration amounted to 0.91 ± 0.23 ng/ml, values ranged between 0.34-1.36 ng/ml and taking peak levels into account measured approximately 300-fold lower than in the horse stallion.

CONCLUSIONS:
The data obtained confirm that the donkey belongs to the group of long day breeders. Irrespective of the close phylogenetical relationship the course of E1S concentrations reveals distinct differences between horse and donkey.

CLINICAL RELEVANCE:
Even between closely related species established reference values for sex steroids cannot be transferred without verification.

© Georg Thieme Verlag KG Stuttgart · New York.

Title

[Concentrations of testosterone, estrone and estrone sulfate in peripheral blood of donkey stallions in relation to season].

Author

Schuler G1, Bernhardt-Welte AW1, Failing K2, Hoffmann B1.

Publish date

2019 Oct

PMID

31589674

Abstract

Application of animal manure on agricultural lands is one of the main sources of estrogen contamination in the environment. Poultry and cow manure contain free and conjugated forms of the natural estrogens (e.g., estrone [E1] and estradiol [E2]) that can enter surface waters during runoff events. Estrone has been identified as the major form of estrogen in the environment; therefore, this study is focused on the evaluation of the degree of mineralization and fate of E1 in a simulated poultry litter and cow manure runoff water. A time-course study was conducted using simulated runoff water that consisted of 0.5 mg cow manure or poultry litter dissolved in 1 L of water spiked with radiolabeled E1 (C-E1). Samples were analyzed for estrogen concentrations at Day 0, 0.5, 1, 2, 3, 5, and 7 using liquid chromatography with tandem mass spectrometry. In the poultry litter simulated runoff water, E1 was biotransformed to 17β-estrone-3-sulfate (E1-3S) but was eventually mineralized to CO; a total E1 mineralization of 92.2% occurred after 7 d of aerobic incubation. In contrast, the concentrations of E1 and other forms of endogenous estrogens detected in the cow manure simulated runoff water, such as E1-3S, 17α-estradiol (α-E2), and 17β-estradiol (β-E2), remained relatively constant and persisted over the 7 d of aerobic incubation. Results of this study demonstrate the differences in the fate of estrone in the simulated poultry litter and cow manure runoff water, highlighting the ability of the endogenous microbial community from poultry litter to mineralize estrogens to CO.

© 2019 The Author(s).

Title

Mineralization and Biotransformation of Estrone in Simulated Poultry Litter and Cow Manure Runoff Water.

Author

Guardian MGE, Aga DS.

Publish date

2019 Jul


Description :

Estrone is an estrogenic hormone.Target: Estrogen Receptor/ERREstrone (E1) is an estrogenic hormone secreted by the ovary as well as adipose tissue with the chemical name of 3-hydroxyestra-1,3,5(10)-triene-17-one and the chemical formula C18H22O2. Estrone is one of several natural estrogens, which also include estriol and estradiol. Estrone is the least abundant of the three hormones; estradiol is present almost always in the reproductive female body, and estriol is abundant primarily during pregnancy. Estrone is relevant to health and disease states because of its conversion to estrone sulfate, a long-lived derivative. Estrone sulfate acts as a reservoir that can be converted as needed to the more active estradiol. It is the predominant estrogen in postmenopausal women [1, 2].