We Offer Worldwide Shipping
Login Wishlist

Ethyl gallate

$43

  • Brand : BIOFRON

  • Catalogue Number : BF-E3008

  • Specification : 98%

  • CAS number : 831-61-8

  • Formula : C9H10O5

  • Molecular Weight : 198.17

  • PUBCHEM ID : 13250

  • Volume : 100mg

In stock

Quantity
Checkout Bulk Order?

Catalogue Number

BF-E3008

Analysis Method

HPLC,NMR,MS

Specification

98%

Storage

2-8°C

Molecular Weight

198.17

Appearance

White crystalline powder

Botanical Source

Euphorbia fischeriana

Structure Type

Phenolics

Category

Standards;Natural Pytochemical;API

SMILES

CCOC(=O)C1=CC(=C(C(=C1)O)O)O

Synonyms

N-ETHYLGALLATE/nipa48/nipagallina/ethyl 3,4,5-trihydroxybenzoate/Nipa No. 48/3,4,5-Trihydroxybenzoic acid ethyl ester/3,4,5-trihydroxyethylbenzoate/Progallin A/Gallic acid ethyl ester/Phyllemblin/Gallic acid ethyl/Ethyl gallate/Benzoic acid, 3,4,5-trihydroxy-, ethyl ester/ethylgallate

IUPAC Name

ethyl 3,4,5-trihydroxybenzoate

Density

1.4±0.1 g/cm3

Solubility

Methanol; DMSO

Flash Point

185.0±20.8 °C

Boiling Point

447.3±40.0 °C at 760 mmHg

Melting Point

149-153 °C

InChl

InChl Key

WGK Germany

RID/ADR

HS Code Reference

2918290000

Personal Projective Equipment

Correct Usage

For Reference Standard and R&D, Not for Human Use Directly.

Meta Tag

provides coniferyl ferulate(CAS#:831-61-8) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of coniferyl ferulate are included as well.>> amp version: coniferyl ferulate

PMID

28960978

Abstract

Alkyl gallates showed elicitor activities on tobacco in both whole plants and cell suspensions. Methyl gallate (MG), ethyl gallate (EG), and propyl gallate (PG) infiltration into tobacco leaves induced hypersensitive reaction-like lesions and topical production of autofluorescent compounds revealed under UV light. When sprayed on tobacco plants at 5 mM, EG promoted upregulation of defense-related genes such as the antimicrobial PR1, β-1,3-glucanase PR2, Chitinase PR3, and osmotin PR5 target genes. Tobacco BY-2 cells challenged with EG underwent cell death in 48 h, which was significantly reduced in the presence of the protease inhibitor aprotinin. The three alkyl gallates all caused alkalinization of the BY-2 extracellular medium, whereas gallic acid did not trigger any pH variation. Using EGTA or LaCl3, we showed that Ca2+ mobilization occurred in BY-2 cells elicited with EG. Overall, our findings are the first evidence of alkyl gallate elicitor properties with early perception events on the plasma membrane, potential hypersensitive reactions, and PR-related downstream defense responses in tobacco.

KEYWORDS

BY-2; alkyl gallates; elicitors; ethyl gallate; pathogenesis-related protein; plant defense reactions; tobacco

Title

Ethyl Gallate Displays Elicitor Activities in Tobacco Plants.

Author

Goupil P1,2, Benouaret R1,2, Richard C3,4.

Publish date

2017 Oct 18

PMID

30587929

Abstract

BACKGROUND:
The aim of this study was to investigate the bioactive constituents of Qingwen Baidu Decoction (QBD) in a rat model of acute lung injury (ALI) induced by lipopolysaccharide (LPS). Our previous studies showed that ethyl gallate (EG) and pentagalloylglucose (PGG) were the active components of QBD for the treatment of ALI.

MATERIALS AND METHODS:
We isolated two compounds and identified the structures of them by nuclear magnetic resonance and mass spectrometer. Lung injury was induced by intratracheal instillation with LPS (5 mg/kg). Rats were randomly divided into six groups: Control group; LPS group; 5 mL/kg DEX + LPS group; 6.6 g/kg QBD extract + LPS group; 17.16 mg/kg PGG + LPS group; 7.26 mg/kg EG + LPS group. The effects of compounds on LPS-induced the number of total cells, neutrophils influx, protein leakage, W/D weight ratio and pulmonary histological changes were examined.

RESULTS:
The results demonstrated that pretreatment with EG and PGG could notably inhibit lung edema and attenuate the pulmonary histological changes (P<0.05). The pretreatment also decreased the number of total cells and polymorphonuclear leukocytes in bronchoalveolar lavage fluid (BALF) (P<0.05).

CONCLUSION:
Ethyl gallate and pentagalloylglucose of QBD played a protective role in preventing LPS-induced ALI. The results supported further study of EG and PGG as potential candidates for preventing ALI.

KEYWORDS

Qingwen Baidu Decoction; acute lung injury; ethyl gallate; pentagalloylglucose

Title

Protective effects of ethyl gallate and pentagalloylglucose, the active components of Qingwen Baidu Decoction, against lipopolysaccharide-induced acute lung injury in rats.

Author

Zhang Q1, Nie J2, Chen SJ2, Li Q2.

Publish date

2018 Dec 19

PMID

32206695

Abstract

In recent years, the exploration for potential inhibitors of HIV has been increased due to the development of drug resistant HIV strains in infected people undergoing antiretroviral agents treatment. In this report, we studied the anti-HIV properties of ethyl gallate (EG) against a panel of HIV-1 strains in in vitro conditions. Different clinical isolates and laboratory strains of HIV-1 were tested for their sensitivity with EG. We found that EG exhibited non-toxic nature over a wide range of cell lines from different tissue origin. Serum proteins have little to no impact on the antiviral activity of EG. In the present study, EG was found to be a promising anti-HIV agent.

© Indian Virological Society 2019.

KEYWORDS

Anti-HIV; Cytotoxicity; Ethyl gallate; HIV-1 clinical isolates; Serum shift

Title

In vitro anti-HIV-1 activity of ethyl gallate.

Author

Krishna CM1,2, Kolla JN2, Asha S1, Reddy TSK2.

Publish date

2020 Mar


Description :

Ethyl gallate is a nonflavonoid phenolic compound and also a scavenger of hydrogen peroxide.