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Eurycomanone

$576

  • Brand : BIOFRON

  • Catalogue Number : BD-D1323

  • Specification : 98%(HPLC)

  • CAS number : 84633-29-4

  • Formula : C20H24O9

  • Molecular Weight : 408.403

  • PUBCHEM ID : 13936691

  • Volume : 20MG

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Catalogue Number

BD-D1323

Analysis Method

HPLC,NMR,MS

Specification

98%(HPLC)

Storage

-20℃

Molecular Weight

408.403

Appearance

White crystalline powder

Botanical Source

Eurycoma longifolia

Structure Type

Diterpenoids

Category

Standards;Natural Pytochemical;API

SMILES

CC1=CC(=O)C(C2(C1CC3C45C2C(C(C(=C)C4(C(C(=O)O3)O)O)O)(OC5)O)C)O

Synonyms

(1β,11α,12α,15β)-1,11,12,14,15-Pentahydroxy-11,20-epoxypicrasa-3,13(21)-diene-2,16-dione dihydrate/pasakbumin-a/EURYCOMANONE/Picrasa-3,13(21)-diene-2,16-dione, 11,20-epoxy-1,11,12,14,15-pentahydroxy-, (1β,11α,12α,15β)-, hydrate (1:2)

IUPAC Name

(1R,4R,5R,7R,8R,11R,13S,17S,18S,19R)-4,5,7,8,17-pentahydroxy-14,18-dimethyl-6-methylidene-3,10-dioxapentacyclo[9.8.0.01,7.04,19.013,18]nonadec-14-ene-9,16-dione

Applications

Eurycomanone could increases spermatogenesis by inhibiting the activity of phosphodiesterase and aromatase in steroidogenesis.

Density

Solubility

Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.

Flash Point

Boiling Point

Melting Point

273-285℃ (methanol ethyl ether )

InChl

InChI=1S/C20H24O9/c1-7-4-10(21)13(23)17(3)9(7)5-11-18-6-28-20(27,16(17)18)12(22)8(2)19(18,26)14(24)15(25)29-11/h4,9,11-14,16,22-24,26-27H,2,5-6H2,1,3H3

InChl Key

UCUWZJWAQQRCOR-UHFFFAOYSA-N

WGK Germany

RID/ADR

HS Code Reference

2938900000

Personal Projective Equipment

Correct Usage

For Reference Standard and R&D, Not for Human Use Directly.

Meta Tag

provides coniferyl ferulate(CAS#:84633-29-4) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of coniferyl ferulate are included as well.>> amp version: coniferyl ferulate

No Technical Documents Available For This Product.

PMID

21523021

Abstract

The title compound, C21H22O5, crystallizes with three mol­ecules in the asymmetric unit. In one mol­ecule, two methyl groups are disordered over two positions with a site occupation factor of 0.72 (2) for the major occupancy site. The benzene rings make dihedral angles of 35.3 (6), 29.7 (6) and 40.6 (7)° in the three molecules.

Title

Bis(2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl) carbonate

Author

Lin-Tao Yang,a Xian-Fu Luo,a Ai-Xi Hu,a,* and Yu Wangb

Publish date

2011 Feb 1

PMID

31269056

Abstract

Background
Additional approaches are needed to identify and provide targeted interventions to populations at continued risk for HIV-associated mortality. We sought to describe care utilization and mortality following an index hospitalization for people with HIV in South Africa.

Methods
We conducted a prospective cohort study among hospitalized patients admitted to medicine wards at a single hospital serving a large catchment area. Participants were followed to 6 months post-discharge. Hospital records were used to describe overall admission numbers and inpatient mortality. Poisson regression was used to assess for associations between readmission or death and independent variables.

Results
Of 124 enrolled participants, 121 lived to hospital discharge. At the time of discharge the median length of stay of sampled patients was 5.5 days and 105 (87%) participants were referred for follow-up, most within 2 weeks of discharge. By 6 months post-discharge, only 18% of participants had attended the clinic to which they were referred and within the referred timeframe; 64 (53%) had been readmitted at least once and 31 (26%) had died. Self-reported skipping care due to difficulty in access (relative risk 1.3, p = 0.02) and not attending follow-up care on time or at the scheduled clinic or not attending clinic at all (relative risk 1.8 and 2.4, respectively, p = 0.001) were associated with readmission or mortality.

Conclusions
The post-hospital period is a period of medical vulnerability and high mortality. Improving post-hospital retention in care may reduce post-hospital mortality.

Title

Readmission and death following hospitalization among people with HIV in South Africa

Author

Christopher J. Hoffmann, Conceptualization, Formal analysis, Funding acquisition, Investigation, Methodology, Writing - original draft,1,* Minja Milovanovic, Data curation, Project administration, Supervision, Writing - review & editing,2 Cody Cichowitz, Conceptualization, Formal analysis, Methodology,3 Anthony Kinghorn, Investigation, Methodology, Writing - review & editing,2 Neil A. Martinson, Conceptualization, Supervision, Writing - review & editing,2 and Ebrahim Variava, Conceptualization, Project administration, Supervision, Writing - review & editing4

Publish date

2019;

PMID

25844226

Abstract

The title compound, C22H18N4OS, crystallized with four independent mol­ecules (A, B, C and D) in the asymmetric unit. All four mol­ecules have a Z conformation about the C=N bond with the benzyl ring being inclined to the indoline ring mean planes by 73.4 (2), 77.9 (2), 73.2 (2) and 77.2 (2)° in mol­ecules A, B, C and D, respectively. In mol­ecules A and B, the phenyl ring is inclined to the mean plane of the indoline ring mean plane by 12.0 (2) and 12.2 (2)°, respectively. However, in mol­ecules C and D, the same dihedral angles are larger, viz. 37.3 (2) and 36.4 (2)°, respectively. Consequently, the benzyl and phenyl rings are almost normal to one another in mol­ecules A and B [dihedral angles = 80.3 (3) and 87.1 (3)°, respectively], while in mol­ecules C and D, the same dihedral angles are only 48.8 (2) and 43.8 (3)°, respectively. There is an intra­molecular N—H⋯O hydrogen bond in each mol­ecule with an S(6) ring motif. There are also short intra­molecular N—H⋯N and C—H⋯S contacts in each mol­ecule. In the crystal, mol­ecules are linked via C—H⋯S hydrogen bonds and C—H⋯π inter­actions, forming a three-dimensional structure. The crystal was refined as a non-merohedral twin with a final BASF value of 0.110 (1).

KEYWORDS

crystal structure, thio­semicarbazones, hydrazine, carbo­thio­amide, 2-oxoindolin-3-yl­idene, hydrogen bonding, C—H⋯π inter­actions

Title

Crystal structure of (Z)-2-(1-benzyl-2-oxoindolin-3-yl­idene)-N-phenyl­hydra­zine-1-carbo­thio­amide

Author

G. Vimala,a J. Haribabu,b R. Karvembu,b B. V. N. Phani Kumar,c and A. SubbiahPandia,*

Publish date

2015 Mar 1;