We Offer Worldwide Shipping
Login Wishlist

Fructose

$43

  • Brand : BIOFRON

  • Catalogue Number : BF-F2005

  • Specification : 98%

  • CAS number : 7660-25-5

  • Formula : C6H12O6

  • Molecular Weight : 180.16

  • PUBCHEM ID : 24310

  • Volume : 20mg

In stock

Quantity
Checkout Bulk Order?

Catalogue Number

BF-F2005

Analysis Method

HPLC,NMR,MS

Specification

98%

Storage

2-8°C

Molecular Weight

180.16

Appearance

White cryst.

Botanical Source

synthesis

Structure Type

Carbohydrates

Category

Standards;Natural Pytochemical;API

SMILES

C1C(C(C(C(O1)(CO)O)O)O)O

Synonyms

(2R,3S,4S,5R)-2,5-bis(hydroxymethyl)oxolane-2,3,4-triol/D(-)-Fructose/D-Fructose/β-d-Fructose/beta-D-fructopyranose/D-(-)-Fructose/Levulose/Fructose [JAN]Fructose, D-/(3S,4R,5R)-1,3,4,5,6-Pentahydroxy-2-hexanon/(3S,4R,5R)-1,3,4,5,6-Pentahydroxyhexan-2-one/Levugen/Fruit sugar/beta-D-fructofuranose/D-(-)-levulose/Fructose (JP15/USP)/b-D-Fructose/DSSTox_CID_3081/fructose powder/arabino-2-Hexulose/1,3,4,5,6-pentahydroxyl-2-hexanone/D-Levulose/(3S,4R,5R)-1,3,4,5,6-Pentahydroxy-2-hexanone/Frutabs/δ-Fructose/Fructooligosaccharides/Fructose/β-δ-fructose/keto-D-fructose/D-fructofuranose/β-Fruit sugar/(2R,3S,4R,5R)-2-(hydroxymethyl)oxane-2,3,4,5-tetrol/D-arabino-Hexulose/Furucton/β-D-arabino-Hexulose/β-Levulose/keto D-fructose/Laevosan/Laevoral/Fructose, furanose form/Fructosteril/(D)-fructose

IUPAC Name

(2R,3S,4R,5R)-2-(hydroxymethyl)oxane-2,3,4,5-tetrol

Density

1.6±0.1 g/cm3

Solubility

Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.

Flash Point

301.5±26.6 °C

Boiling Point

551.7±50.0 °C at 760 mmHg

Melting Point

100 - 110ºC

InChl

InChI=1S/C6H12O6/c7-2-6(11)5(10)4(9)3(8)1-12-6/h3-5,7-11H,1-2H2/t3-,4-,5+,6-/m1/s1

InChl Key

LKDRXBCSQODPBY-ARQDHWQXSA-N

WGK Germany

RID/ADR

HS Code Reference

2940000000

Personal Projective Equipment

Correct Usage

For Reference Standard and R&D, Not for Human Use Directly.

Meta Tag

provides coniferyl ferulate(CAS#:7660-25-5) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of coniferyl ferulate are included as well.>> amp version: coniferyl ferulate

PMID

16146352

Abstract

Recently 2 QSPR-based in silico models were developed in our laboratories to predict the aqueous and non-aqueous solubility of drug-like organic compounds. For the intrinsic aqueous solubility model, a set of 321 structurally diverse drugs was collected from literature for the analysis. For the PEG 400 cosolvent model, experimental data for 122 drugs were obtained by a uniform experimental procedure at 4 volume fractions of PEG 400 in water, 0%, 25%, 50%, and 75%. The drugs used in both models represent a wide range of compounds, with log P values from −5 to 7.5, and molecular weights from 100 to >600 g/mol. Because of the standardized procedure used to collect the cosolvent data and the careful assessment of quality used in obtaining literature data, both data sets have potential value for the scientific community for use in building various models that require experimental solubility data.

KEYWORDS

solubility, aqueous, cosolvent, PEG 400, data, QSPR model

Title

Aqueous and cosolvent solubility data for drug-like organic compounds

Author

Erik Rytting,1 Kimberley A. Lentz,corresponding author1 Xue-Qing Chen,3 Feng Qian,3 and Srini Venkatesh1

Publish date

2005 Mar;

PMID

7769696

Abstract

The herpes simplex virus type 1 protease and its substrate, ICP35, are involved in the assembly of viral capsids. Both proteins are encoded by a single open reading frame from overlapping mRNAs. The protease is autoproteolytically processed at two sites. The protease cleaves itself at the C-terminal site (maturation site) and also cleaves ICP35 at an identical site, releasing a 25-amino-acid (aa) peptide from each protein. To determine whether these 25 aa play a role in capsid assembly, we constructed a mutant virus expressing only Prb, the protease without the C-terminal 25 aa. Phenotypic analysis of the Prb virus in the presence and absence of ICP35 shows the following: (i) Prb retains the functional activity of the wild-type protease which supports virus growth in the presence of ICP35; (ii) in contrast to the ICP35 null mutant delta ICP35 virus, the Prb virus fails to grow in the absence of ICP35; and (iii) trans-complementation experiments indicated that full-length ICP35 (ICP35 c,d), but not the cleaved form (ICP35 e,f), complements the growth of the Prb virus. The most striking phenotype of the Prb virus is that only unsealed aberrant capsid structures are observed by electron microscopy in mutant-infected Vero cells. Our results demonstrate that the growth of herpes simplex virus type 1 requires the C-terminal 25 aa of either the protease or its substrate, ICP35, and that the C-terminal 25 aa are involved in the formation of sealed capsids.

Title

The C-terminal 25 amino acids of the protease and its substrate ICP35 of herpes simplex virus type 1 are involved in the formation of sealed capsids.

Author

L Matusick-Kumar, W W Newcomb, J C Brown, P J McCann, 3rd, W Hurlburt, S P Weinheimer, and M Gao

Publish date

1995 Jul;

PMID

26179626

Abstract

The medial prefrontal cortex (mPFC) is implicated in processing sensory-discriminative and affective pain. Nonetheless, the underlying mechanisms are poorly understood. Here we demonstrate a role for excitatory neurons in the prelimbic cortex (PL), a sub-region of mPFC, in the regulation of pain sensation and anxiety-like behaviours. Using a chronic inflammatory pain model, we show that lesion of the PL contralateral but not ipsilateral to the inflamed paw attenuates hyperalgesia and anxiety-like behaviours in rats. Optogenetic activation of contralateral PL excitatory neurons exerts analgesic and anxiolytic effects in mice subjected to chronic pain, whereas inhibition is anxiogenic in naive mice. The intrinsic excitability of contralateral PL excitatory neurons is decreased in chronic pain rats; knocking down cyclin-dependent kinase 5 reverses this deactivation and alleviates behavioural impairments. Together, our findings provide novel insights into the role of PL excitatory neurons in the regulation of sensory and affective pain.

Title

Deactivation of excitatory neurons in the prelimbic cortex via Cdk5 promotes pain sensation and anxiety

Author

Guo-Qiang Wang,1,* Cheng Cen,1,* Chong Li,1,* Shuai Cao,1,* Ning Wang,1 Zheng Zhou,2 Xue-Mei Liu,2 Yu Xu,1 Na-Xi Tian,1 Ying Zhang,1 Jun Wang,3 Li-Ping Wang,a,2 and Yun Wangb,1,

Publish date

2015


Description :

Fructose is a simple ketonic monosaccharide found in many plants, where it is often bonded to glucose to form the disaccharide sucrose.