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Fumaric acid

$43

  • Brand : BIOFRON

  • Catalogue Number : BF-F3005

  • Specification : 98%

  • CAS number : 110-17-8

  • Formula : C4H4O4

  • Molecular Weight : 116.07

  • PUBCHEM ID : 444972

  • Volume : 100mg

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Catalogue Number

BF-F3005

Analysis Method

HPLC,NMR,MS

Specification

98%

Storage

2-8°C

Molecular Weight

116.07

Appearance

White flake crystal

Botanical Source

Corydalis yanhusuo

Structure Type

Others

Category

Standards;Natural Pytochemical;API

SMILES

C(=CC(=O)O)C(=O)O

Synonyms

U-1149/FUMARSAEURE/but-2-en-1,4-dioic acid/TMEDA/trans-2-Butenedioic Acid/Fumarsure/trans-butenedioic acid/Fumaric acid/fumaric/Boletic acid

IUPAC Name

(E)-but-2-enedioic acid

Density

1.5±0.1 g/cm3

Solubility

Acetontrile

Flash Point

183.0±19.7 °C

Boiling Point

355.5±25.0 °C at 760 mmHg

Melting Point

298-300 °C (subl.)(lit.)

InChl

InChl Key

WGK Germany

RID/ADR

HS Code Reference

2917190000

Personal Projective Equipment

Correct Usage

For Reference Standard and R&D, Not for Human Use Directly.

Meta Tag

provides coniferyl ferulate(CAS#:110-17-8) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of coniferyl ferulate are included as well.>> amp version: coniferyl ferulate

PMID

28847082

Abstract

Fumaric acid is an important building-block chemical. The production of fumaric acid by fermentation is possible. Loofah fiber is a natural, biodegradable, renewable polymer material with highly sophisticated and pore structure. This work investigated a new immobilization method using loofah fiber as carrier to produce fumaric acid in a stirred-tank reactor. Compared with other carriers, loofah fiber was proven to be efficiently and successfully used in the reactor. After the optimization process, 20g addition of loofah fiber and 400rpm agitation speed were chosen as the most suitable process conditions. 30.3g/L fumaric acid in the broth as well as 19.16g fumaric acid in the precipitation of solid was achieved, while the yield from glucose reached 0.211g/g. Three batches of fermentation using the same loofah fiber carrier were conducted successfully, which meant it provided a new method to produce fumaric acid in a stirred-tank reactor.

KEYWORDS

Fermentation; Fumaric acid; Rhizopus arrhizus; Stirred-tank reactor.

Title

Production of Fumaric Acid by Immobilized Rhizopus Arrhizus RH 7-13-9# on Loofah Fiber in a Stirred-Tank Reactor

Author

Huan Liu 1 , Shijie Zhao 1 , Yuhan Jin 1 , Xuemin Yue 1 , Li Deng 2 , Fang Wang 1 , Tianwei Tan 1

Publish date

2017 Nov

PMID

27604834

Abstract

Production of fumaric acid from alkali-pretreated corncob (APC) at high solids loading was investigated using a combination of separated hydrolysis and fermentation (SHF) and fed-batch simultaneous saccharification and fermentation (SSF) by Rhizopus oryzae. Four different fermentation modes were tested to maximize fumaric acid concentration at high solids loading. The highest concentration of 41.32 g/L fumaric acid was obtained from 20 % (w/v) APC at 38 °C in the combined SHF and fed-batch SSF process, compared with 19.13 g/L fumaric acid in batch SSF alone. The results indicated that a combination of SHF and fed-batch SSF significantly improved production of fumaric acid from lignocellulose by R. oryzae than that achieved with batch SSF at high solids loading.

KEYWORDS

Alkali-pretreated corncob; Fed-batch simultaneous saccharification and fermentation; Fumaric acid; High solids loading; Rhizopus oryzae.

Title

Fumaric Acid Production From Alkali-Pretreated Corncob by Fed-Batch Simultaneous Saccharification and Fermentation Combined With Separated Hydrolysis and Fermentation at High Solids Loading

Author

Xin Li 1 2 3 , Jin Zhou 4 , Shuiping Ouyang 4 , Jia Ouyang 5 6 4 , Qiang Yong 5 6 4

Publish date

2017 Feb

PMID

30506453

Abstract

Fumaric acid is a valuable compound used in foods, beverages, detergents, animal feed, pharmaceuticals and miscellaneous industrial products. It is produced on a large scale by the petrochemical route but the current tendency is towards implementing “green production” and environmental friendly technologies like biotechnological production of fumaric acid using low-cost raw materials. In this context, numerous studies focus on improving the fermentation process not only by using renewable raw material and genetically modified microorganisms, but also by developing and applying different downstream techniques for easy recovery of fumaric acid from the fermented broth. This review presents the main methods for production and separation of fumaric acid, highlighting the advantages and disadvantages of these and the potential economic impact in industry.

KEYWORDS

Fermentation; Fumaric acid; Rhizopus; Separation.

Title

Fumaric Acid: Production and Separation

Author

Roxana-Andreea Ilica 1 , Lenuţa Kloetzer 2 , Anca-Irina Galaction 3 , Dan CaScaval 1

Publish date

2019 Jan


Description :

Fumaric acid, associated with fumarase deficiency, is identified as an oncometabolite or an endogenous, cancer causing metabolite.