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Gancaonin O

$1,152

  • Brand : BIOFRON

  • Catalogue Number : BN-O0898

  • Specification : 98%(HPLC)

  • CAS number : 129145-53-5

  • Formula : C20H18O6

  • Molecular Weight : 354.35

  • PUBCHEM ID : 480853

  • Volume : 5mg

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Catalogue Number

BN-O0898

Analysis Method

HPLC,NMR,MS

Specification

98%(HPLC)

Storage

2-8°C

Molecular Weight

354.35

Appearance

Yellow powder

Botanical Source

Structure Type

Category

Standards;Natural Pytochemical;API

SMILES

CCC(=CCC1=C(C2=C(C=C1O)OC(=CC2=O)C3=CC(=C(C=C3)O)O)O)C

Synonyms

GancaoninO

IUPAC Name

2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-6-(3-methylpent-2-enyl)chromen-4-one

Density

1.425g/cm3

Solubility

Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.

Flash Point

229.986ºC

Boiling Point

633.422ºC at 760 mmHg

Melting Point

InChl

InChI=1S/C21H20O6/c1-3-11(2)4-6-13-15(23)9-19-20(21(13)26)17(25)10-18(27-19)12-5-7-14(22)16(24)8-12/h4-5,7-10,22-24,26H,3,6H2,1-2H3/b11-4+

InChl Key

ZLWRESLPIXVSSX-NYYWCZLTSA-N

WGK Germany

RID/ADR

HS Code Reference

2933990000

Personal Projective Equipment

Correct Usage

For Reference Standard and R&D, Not for Human Use Directly.

Meta Tag

provides coniferyl ferulate(CAS#:129145-53-5) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of coniferyl ferulate are included as well.>> amp version: coniferyl ferulate

No Technical Documents Available For This Product.

PMID

24672780

Abstract

Numerous studies have reported that mesenchymal stem cells (MSCs) can ameliorate neurological deficits in ischemic stroke models. Among the various hypotheses that have been suggested to explain the therapeutic mechanism underlying these observations, neurogenesis is thought to be critical. To enhance the therapeutic benefits of human bone marrow-derived MSCs (hBM-MSCs), we efficiently modified hBM-MSCs by introduction of the brain-derived neurotrophic factor (BDNF) gene via adenoviral transduction mediated by cell-permeable peptides and investigated whether BDNF-modified hBM-MSCs (MSCs-BDNF) contributed to functional recovery and endogenous neurogenesis in a rat model of middle cerebral artery occlusion (MCAO). Transplantation of MSCs induced the proliferation of 5-bromo-2′-deoxyuridine (BrdU-) positive cells in the subventricular zone. Transplantation of MSCs-BDNF enhanced the proliferation of endogenous neural stem cells more significantly, while suppressing cell death. Newborn cells differentiated into doublecortin (DCX-) positive neuroblasts and Neuronal Nuclei (NeuN-) positive mature neurons in the subventricular zone and ischemic boundary at higher rates in animals with MSCs-BDNF compared with treatment using solely phosphate buffered saline (PBS) or MSCs. Triphenyltetrazolium chloride staining and behavioral analysis revealed greater functional recovery in animals with MSCs-BDNF compared with the other groups. MSCs-BDNF exhibited effective therapeutic potential by protecting cell from apoptotic death and enhancing endogenous neurogenesis.

Title

Mesenchymal Stem Cells Expressing Brain-Derived Neurotrophic Factor Enhance Endogenous Neurogenesis in an Ischemic Stroke Model

Author

Chang Hyun Jeong, 1 Seong Muk Kim, 2 Jung Yeon Lim, 1 Chung Heon Ryu, 2 Jin Ae Jun, 1 and Sin-Soo Jeun 1 , 3 ,*

Publish date

2014;

PMID

30271249

Abstract

Dissochaeta is a plant genus of woody climbers, classified in the tribe Dissochaeteae (Melastomataceae). The taxonomic history of the genus is complicated and includes some allied genera like Dalenia, Diplectria, Macrolenes and Omphalopus. Most of them are already regarded as synonyms of Dissochaeta except for Macrolenes which is considered a separate genus here as well. Dissochaeta is characterised by its scrambling habit, interpetiolar outgrowths, 4-merous flowers, dimorphic stamens and berry-like fruits. A taxonomic revision of Dissochaeta is presented, which includes references, a complete list of synonyms, detailed morphological descriptions of the species and an identification key, as well as information on the distribution, habitat and ecology, vernacular names, notes and lists of examined specimens. Fifty four species and two varieties of Dissochaeta are recognised. We designate several lectotypes, propose eleven new combinations and we describe one new species and one new variety.

KEYWORDS

Dissochaeta , Macrolenes , Melastomataceae , revision, South-East Asia, taxonomy

Title

A revision of Dissochaeta (Melastomataceae, Dissochaeteae)

Author

Abdulrokhman Kartonegoro,corresponding author1,2 Jan Frits Veldkamp,1 Peter Hovenkamp,1 and Peter van Welzen

Publish date

2018;

PMID

21201030

Abstract

In the mol­ecule of the title compound, [Cu(C12H6N2O4)(C2H8N2)(H2O)2]·2.5H2O, the CuII atom is six-coordinated in a distorted octa­hedral configuration by two N atoms from a 2,2′-bipyridine-5,5′-dicarboxyl­ate anion, two N atoms from ethyl­enediamine and two O atoms from two water mol­ecules. There are also two and a half water mol­ecules in the asymmetric unit. The planar five-membered ring is nearly coplanar with the adjacent pyridine rings, while the other five-membered ring adopts a twisted conformation, probably due to hydrogen bonding. In the crystal structure, intra- and inter­molecular N—H⋯O and O—H⋯O hydrogen bonds link the mol­ecules.

Title

Diaqua­(2,2′-bipyridine-5,5′-dicarboxyl­ato-κ2 N,N′)(ethyl­enediamine-κ2 N,N′)copper(II) 2.5-hydrate

Author

Mohammad Yousefi,a Aida Khalighi,a Nasim Tadayon Pour,a Vahid Amani,a,* and Hamid Reza Khavasib

Publish date

2008 Oct 1;


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