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Guanine

$43

  • Brand : BIOFRON

  • Catalogue Number : BF-G3010

  • Specification : 98%

  • CAS number : 73-40-5

  • Formula : C5H5N5O

  • Molecular Weight : 151.13

  • PUBCHEM ID : 135398634

  • Volume : 100mg

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Catalogue Number

BF-G3010

Analysis Method

HPLC,NMR,MS

Specification

98%

Storage

2-8°C

Molecular Weight

151.13

Appearance

White powder

Botanical Source

Structure Type

Nucleosiede

Category

Standards;Natural Pytochemical;API

SMILES

C1=NC2=C(N1)C(=O)NC(=N2)N

Synonyms

dewpearl/Guanin/2-amino-Hypoxanthine/9H-purin-6-ol, 2-amino-/2-amino-3,7-dihydro-6H-purin-6-one/7H-Purin-6-ol, 2-amino-/Guanine/2-amino-9H-purin-6-ol/Guanie/2-amino-6-oxypurine/Gua/guamine/2-amino-1,7-dihydro-6H-purin-6-one/2-amino-1,9-dihydro-6H-purin-6-one/quanine/2-amino-6-hydroxypurine/Ganciclovir Impurity 6

IUPAC Name

2-amino-1,7-dihydropurin-6-one

Density

2.2±0.1 g/cm3

Solubility

Aqueous base

Flash Point

293.4±27.9 °C

Boiling Point

561.5±42.0 °C at 760 mmHg

Melting Point

>300 °C(lit.)

InChl

InChl Key

WGK Germany

RID/ADR

HS Code Reference

2933990000

Personal Projective Equipment

Correct Usage

For Reference Standard and R&D, Not for Human Use Directly.

Meta Tag

provides coniferyl ferulate(CAS#:73-40-5) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of coniferyl ferulate are included as well.>> amp version: coniferyl ferulate

PMID

32255446

Abstract

The main insights into the photoactivated dynamics of guanine quadruplexes (G4s) recently provided by quantum mechanical computations are concisely reviewed here. The experimental steady state absorption and circular dichroism spectra of different topologies can be reproduced and assigned. After light absorption from excited states delocalized over multiple bases, the most important decay pathways involve localization of the excitation over a single base or on two stacked guanines, excimers with different degrees of charge transfer character. Two main photochemical reactions are discussed. One involves the photodimerization of two stacked guanine bases on the ‘neutral’ excimer path. The other, ionization of guanine, which triggers deprotonation of the resulting cation to form (G-H2)˙ and (G-H1)˙ radicals. Both the static and dynamical properties of G4 excited states are ruled by their topology and modulated by the inner coordinated metal ions.

Title

Studying the excited electronic states of guanine rich DNA quadruplexes by quantum mechanical methods: main achievements and perspectives.

Author

Martinez-Fernandez L1, Esposito L2, Improta R2.

Publish date

2020 Apr 15


Description :

Guanine is one of the fundamental components of nucleic acids (DNA and RNA). Guanine is a purine derivative, consisting of a fused pyrimidine-imidazole ring system with conjugated double bonds.